RESUMO
We present two middle-aged patients with pruritic, crusted scalp erosions. Skin biopsy showed epidermal acantholysis with IgG and C3 intercellular deposits on direct immunofluorescence, leading to the diagnosis of localized pemphigus vulgaris. Resolution of the lesions without relapse occurred after low doses of oral prednisone and intralesional triamcinolone acetonide.
Assuntos
Pênfigo , Dermatoses do Couro Cabeludo , Humanos , Pênfigo/patologia , Pênfigo/diagnóstico , Pênfigo/tratamento farmacológico , Dermatoses do Couro Cabeludo/patologia , Dermatoses do Couro Cabeludo/tratamento farmacológico , Dermatoses do Couro Cabeludo/diagnóstico , Pessoa de Meia-Idade , Masculino , Triancinolona Acetonida/uso terapêutico , Triancinolona Acetonida/administração & dosagem , Feminino , Prednisona/uso terapêutico , Glucocorticoides/uso terapêutico , Couro Cabeludo/patologia , Acantólise/patologia , Acantólise/diagnósticoRESUMO
Pilomatrix carcinoma is a rare malignant tumor that originates from hair matrix cells. It is not usually considered in a differential diagnosis owing to its low incidence. We present a case of this uncommon entity and review the literature.
Assuntos
Neoplasias Faciais/diagnóstico , Doenças do Cabelo/diagnóstico , Neoplasias Cutâneas/diagnóstico , Idoso de 80 Anos ou mais , Biópsia , Diagnóstico Diferencial , Humanos , MasculinoRESUMO
BACKGROUND: Angiolymphoid hyperplasia with eosinophilia is a rare, benign disorder characterized by reddish-brown nodules and plaques in the dermis and the subcutaneous tissues, typically occurring on the neck and head. Surgical excision, corticosteroids, radiotherapy, and other therapies have been used, however, recurrences are common. Treatment with vascular lasers such as pulsed dye laser (PDL) or Nd:YAG seems to be a promising therapeutic option. OBJECTIVE: To assess the efficacy and safety of PDL and combined sequential PDL-Nd:YAG laser in patients with ALHE. METHODS: Three patients with ALHE were treated with PDL at 595-nm wavelength or with a combined sequential application of 595-nm PDL and 1,064-nm Nd:YAG wavelengths. Topical anesthetic was applied before laser treatment. RESULTS: Complete resolution of the lesions was achieved in two patients with ALHE; a partial response was seen in one patient. No significant side-effects were reported. CONCLUSIONS: We consider that PDL should be a first-line therapy for AHLE. Sequential application of PDL and Nd:YAG laser seems to show promising results, so it could be an interesting new treatment option.
Assuntos
Hiperplasia Angiolinfoide com Eosinofilia/cirurgia , Lasers de Corante/uso terapêutico , Adulto , Idoso , Hiperplasia Angiolinfoide com Eosinofilia/patologia , Orelha , Feminino , Humanos , Indução de Remissão , Resultado do Tratamento , Adulto JovemRESUMO
Cutis verticis gyrata is a rare skin condition characterized by ridges and furrows resembling the surface of the brain. It can be considered as a manifestation of a variety of diverse causes such as cerebriform intradermal nevus. We report a 48-year-old man with cerebriform and soft folds on the left parietal and temporal areas. Histology showed solitary or clusters of nevus cells in the dermis. The diagnosis of cerebriform intradermal nevus was confirmed.