Detalhe da pesquisa
1.
Cationic Carbosilane Dendritic Systems as Promising Anti-Amyloid Agents in Typeâ 2 Diabetes.
Chemistry
; 26(34): 7609-7621, 2020 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32259327
2.
Amyloid-induced ß-cell dysfunction and islet inflammation are ameliorated by 4-phenylbutyrate (PBA) treatment.
FASEB J
; 31(12): 5296-5306, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28821639
3.
BACE2 suppression promotes ß-cell survival and function in a model of type 2 diabetes induced by human islet amyloid polypeptide overexpression.
Cell Mol Life Sci
; 74(15): 2827-2838, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28337562
4.
Inhibition of BACE2 counteracts hIAPP-induced insulin secretory defects in pancreatic ß-cells.
FASEB J
; 29(1): 95-104, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25342134
5.
Islet amyloid polypeptide exerts a novel autocrine action in ß-cell signaling and proliferation.
FASEB J
; 29(7): 2970-9, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25808537
6.
Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: trichostatin A as a case study.
Biochim Biophys Acta
; 1840(6): 1634-9, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24368265
7.
A lyophilized red grape pomace containing proanthocyanidin-rich dietary fiber induces genetic and metabolic alterations in colon mucosa of female C57BL/6J mice.
J Nutr
; 141(9): 1597-604, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21775529
8.
4-Phenylbutyrate (PBA) treatment reduces hyperglycemia and islet amyloid in a mouse model of type 2 diabetes and obesity.
Sci Rep
; 11(1): 11878, 2021 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34088954
9.
BACE2 suppression in mice aggravates the adverse metabolic consequences of an obesogenic diet.
Mol Metab
; 53: 101251, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34015524
10.
Peripheral insulin and amylin levels in Parkinson's disease.
Parkinsonism Relat Disord
; 79: 91-96, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911247
11.
Alpha1-antitrypsin ameliorates islet amyloid-induced glucose intolerance and ß-cell dysfunction.
Mol Metab
; 37: 100984, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32229246
12.
Mitochondrial Dysfunction: A Common Hallmark Underlying Comorbidity between sIBM and Other Degenerative and Age-Related Diseases.
J Clin Med
; 9(5)2020 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32413985
13.
Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets.
Carcinogenesis
; 30(6): 946-52, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19369582
14.
Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29.
Int J Cancer
; 124(12): 2789-96, 2009 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19253370
15.
Pancreatic ß cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics.
Cell Death Dis
; 9(5): 481, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29705815
16.
Protein disulfide isomerase ameliorates ß-cell dysfunction in pancreatic islets overexpressing human islet amyloid polypeptide.
Mol Cell Endocrinol
; 420: 57-65, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26607804
17.
Design of an interface peptide as new inhibitor of human glucose-6-phosphate dehydrogenase.
J Mol Graph Model
; 49: 110-7, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24637073
18.
Chaperones ameliorate beta cell dysfunction associated with human islet amyloid polypeptide overexpression.
PLoS One
; 9(7): e101797, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25010593
19.
Epicatechin gallate impairs colon cancer cell metabolic productivity.
J Agric Food Chem
; 61(18): 4310-7, 2013 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23594085
20.
Diphenyl urea derivatives as inhibitors of transketolase: a structure-based virtual screening.
PLoS One
; 7(3): e32276, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22403640