Detalhe da pesquisa
1.
A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.
Arch Toxicol
; 91(3): 1385-1400, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27344343
2.
Transcriptomic hepatotoxicity signature of chlorpromazine after short- and long-term exposure in primary human sandwich cultures.
Drug Metab Dispos
; 41(10): 1835-42, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23913027
3.
Plateable cryopreserved human hepatocytes for the assessment of cytochrome P450 inducibility: experimental condition-related variables affecting their response to inducers.
Xenobiotica
; 42(10): 968-79, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22515431
4.
Improved xenogenic hepatocyte implantation into nude mouse liver parenchyma with acute liver failure when followed by repeated anti-Fas antibody (Jo2) treatment.
Cell Transplant
; 17(5): 507-24, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18714670
5.
Differential effects of curcumin on cryopreserved versus fresh primary human hepatocytes.
Phytother Res
; 22(12): 1688-91, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18697189
6.
Cryopreserved human hepatocytes in suspension are a convenient high throughput tool for the prediction of metabolic clearance.
Eur J Pharm Biopharm
; 63(3): 347-55, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16621491
7.
Experimental models of acute and chronic liver failure in nude mice to study hepatocyte transplantation.
Cell Transplant
; 14(5): 277-90, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16052909
8.
Isolation and culture of primary human hepatocytes.
Methods Mol Biol
; 290: 207-29, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15361665
9.
Prediction of drug induced liver injury using molecular and biological descriptors.
Comb Chem High Throughput Screen
; 18(3): 315-22, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25747442
10.
Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure.
Toxicol In Vitro
; 30(1 Pt A): 52-61, 2015 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25458484
11.
Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication.
Toxicol Sci
; 147(2): 412-24, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26160117
12.
Hydrogel networks of poly(ethylene oxide) star-molecules supported by expanded polytetrafluoroethylene membranes: characterization, biocompatibility evaluation and glucose diffusion characteristics.
Macromol Biosci
; 4(7): 639-48, 2004 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-15468257
13.
Failure of liver cirrhosis induction by thioacetamide in Nagase analbuminaemic rats.
Lab Anim
; 36(2): 158-64, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11943080
14.
The establishment of a network of European human research tissue banks.
Cell Tissue Bank
; 3(2): 133-7, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-15256890
15.
Increased survival despite failure of transplanted human hepatocyte implantation into liver parenchyma of nude mice with repeated lethal Jo2-induced liver deficiency.
Cell Transplant
; 23(12): 1557-72, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-23636101
16.
Isolation and culture of primary hepatocytes from resected human liver tissue.
Methods Mol Biol
; 640: 57-82, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20645046
17.
Follow-up to the pre-validation of a harmonised protocol for assessment of CYP induction responses in freshly isolated and cryopreserved human hepatocytes with respect to culture format, treatment, positive reference inducers and incubation conditions.
Toxicol In Vitro
; 24(1): 346-56, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19497360
18.
Inter-laboratory evaluation of the response of primary human hepatocyte cultures to model CYP inducers - a European Centre for Validation of Alternative Methods (ECVAM) - funded pre-validation study.
Toxicol In Vitro
; 24(1): 335-45, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19497361
19.
REMOVED: Glutathione prevents cytochrome P450 3A induction by dexamethasone in primary cultures of rat hepatocytes.
Toxicol In Vitro
; 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16978831
20.
Fourth meeting of the European Network of Research Tissue Banks - future strategy to increase collaborations in the supply of human tissue for biomedical research.
Cell Tissue Bank
; 6(2): 131-8, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15909101