Detalhe da pesquisa
1.
In vitro CYP450 enzyme down-regulation by GLP-1/glucagon co-agonist does not translate to observed drug-drug interactions in the clinic.
Drug Metab Dispos
; 2022 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35680133
2.
Population pharmacokinetics and covariate analysis of Sym004, an antibody mixture against the epidermal growth factor receptor, in subjects with metastatic colorectal cancer and other solid tumors.
J Pharmacokinet Pharmacodyn
; 47(1): 5-18, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31679083
3.
Histopathological nerve and skeletal muscle changes in rats subjected to persistent insulin-induced hypoglycemia.
J Toxicol Pathol
; 29(1): 17-30, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26989298
4.
Statistical evaluation and experimental design of a psoriasis xenograft transplantation model treated with cyclosporin A.
Exp Dermatol
; 20(5): 441-4, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21426413
5.
Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain.
Int J Endocrinol
; 2017: 7861236, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28421113
6.
Toxicological Effects during and following Persistent Insulin-Induced Hypoglycaemia in Healthy Euglycaemic Rats.
Basic Clin Pharmacol Toxicol
; 121(1): 53-66, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28218988
7.
Sym015: A Highly Efficacious Antibody Mixture against MET-Amplified Tumors.
Clin Cancer Res
; 23(19): 5923-5935, 2017 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28679766
8.
A weighted method for estimation of receptor occupancy for pharmacodynamic measurements in drug development.
Cytometry B Clin Cytom
; 90(2): 220-9, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26205127
9.
New alpha(1)-adrenoceptor antagonists derived from the antipsychotic sertindole - carbon-11 labelling and pet examination of brain uptake in the cynomolgus monkey.
Nucl Med Biol
; 31(3): 327-36, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15028245
10.
A reversible albumin-binding growth hormone derivative is well tolerated and possesses a potential once-weekly treatment profile.
J Clin Endocrinol Metab
; 99(10): E1819-29, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25013997
11.
Measurement of lumefantrine and its metabolite in plasma by high performance liquid chromatography with ultraviolet detection.
J Pharm Biomed Anal
; 54(1): 168-72, 2011 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20832961
12.
The synthesis and SAR of 2-arylsulfanyl-phenyl piperazinyl acetic acids as glyT-1 inhibitors.
Bioorg Med Chem Lett
; 14(15): 4027-30, 2004 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15225720