Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Immune checkpoint therapy-current perspectives and future directions.

Sharma, Padmanee; Goswami, Sangeeta; Raychaudhuri, Deblina; Siddiqui, Bilal A; Singh, Pratishtha; Nagarajan, Ashwat; Liu, Jielin; Subudhi, Sumit K; Poon, Candice; Gant, Kristal L; Herbrich, Shelley M; Anandhan, Swetha; Islam, Shajedul; Amit, Moran; Anandappa, Gayathri; Allison, James P.

Cell ; 186(8): 1652-1669, 2023 04 13.

Artigo em Inglês | MEDLINE | ID: mdl-37059068

2.

Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade.

Wei, Spencer C; Levine, Jacob H; Cogdill, Alexandria P; Zhao, Yang; Anang, Nana-Ama A S; Andrews, Miles C; Sharma, Padmanee; Wang, Jing; Wargo, Jennifer A; Pe'er, Dana; Allison, James P.

Cell ; 170(6): 1120-1133.e17, 2017 Sep 07.

Artigo em Inglês | MEDLINE | ID: mdl-28803728

3.

Loss of IFN-Î³ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.

Gao, Jianjun; Shi, Lewis Zhichang; Zhao, Hao; Chen, Jianfeng; Xiong, Liangwen; He, Qiuming; Chen, Tenghui; Roszik, Jason; Bernatchez, Chantale; Woodman, Scott E; Chen, Pei-Ling; Hwu, Patrick; Allison, James P; Futreal, Andrew; Wargo, Jennifer A; Sharma, Padmanee.

Cell ; 167(2): 397-404.e9, 2016 Oct 06.

Artigo em Inglês | MEDLINE | ID: mdl-27667683

4.

Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential.

Sharma, Padmanee; Allison, James P.

Cell ; 161(2): 205-14, 2015 Apr 09.

Artigo em Inglês | MEDLINE | ID: mdl-25860605

5.

Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States.

Wei, Spencer C; Sharma, Roshan; Anang, Nana-Ama A S; Levine, Jacob H; Zhao, Yang; Mancuso, James J; Setty, Manu; Sharma, Padmanee; Wang, Jing; Pe'er, Dana; Allison, James P.

Immunity ; 50(4): 1084-1098.e10, 2019 04 16.

Artigo em Inglês | MEDLINE | ID: mdl-30926234

6.

T cells specific for α-myosin drive immunotherapy-related myocarditis.

Axelrod, Margaret L; Meijers, Wouter C; Screever, Elles M; Qin, Juan; Carroll, Mary Grace; Sun, Xiaopeng; Tannous, Elie; Zhang, Yueli; Sugiura, Ayaka; Taylor, Brandie C; Hanna, Ann; Zhang, Shaoyi; Amancherla, Kaushik; Tai, Warren; Wright, Jordan J; Wei, Spencer C; Opalenik, Susan R; Toren, Abigail L; Rathmell, Jeffrey C; Ferrell, P Brent; Phillips, Elizabeth J; Mallal, Simon; Johnson, Douglas B; Allison, James P; Moslehi, Javid J; Balko, Justin M.

Nature ; 611(7937): 818-826, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-36385524

7.

Neoadjuvant relatlimab and nivolumab in resectable melanoma.

Amaria, Rodabe N; Postow, Michael; Burton, Elizabeth M; Tetzlaff, Michael T; Ross, Merrick I; Torres-Cabala, Carlos; Glitza, Isabella C; Duan, Fei; Milton, Denái R; Busam, Klaus; Simpson, Lauren; McQuade, Jennifer L; Wong, Michael K; Gershenwald, Jeffrey E; Lee, Jeffrey E; Goepfert, Ryan P; Keung, Emily Z; Fisher, Sarah B; Betof-Warner, Allison; Shoushtari, Alexander N; Callahan, Margaret; Coit, Daniel; Bartlett, Edmund K; Bello, Danielle; Momtaz, Parisa; Nicholas, Courtney; Gu, Aidi; Zhang, Xuejun; Korivi, Brinda Rao; Patnana, Madhavi; Patel, Sapna P; Diab, Adi; Lucci, Anthony; Prieto, Victor G; Davies, Michael A; Allison, James P; Sharma, Padmanee; Wargo, Jennifer A; Ariyan, Charlotte; Tawbi, Hussein A.

Nature ; 611(7934): 155-160, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-36289334

8.

Checkpoints.

Allison, James P.

Cell ; 162(6): 1202-5, 2015 Sep 10.

Artigo em Inglês | MEDLINE | ID: mdl-26359978

9.

Author Correction: Neoadjuvant relatlimab and nivolumab in resectable melanoma.

Amaria, Rodabe N; Postow, Michael; Burton, Elizabeth M; Tetzlaff, Michael T; Ross, Merrick I; Torres-Cabala, Carlos; Glitza, Isabella C; Duan, Fei; Milton, Denái R; Busam, Klaus; Simpson, Lauren; McQuade, Jennifer L; Wong, Michael K; Gershenwald, Jeffrey E; Lee, Jeffrey E; Goepfert, Ryan P; Keung, Emily Z; Fisher, Sarah B; Betof-Warner, Allison; Shoushtari, Alexander N; Callahan, Margaret; Coit, Daniel; Bartlett, Edmund K; Bello, Danielle; Momtaz, Parisa; Nicholas, Courtney; Gu, Aidi; Zhang, Xuejun; Korivi, Brinda Rao; Patnana, Madhavi; Patel, Sapna P; Diab, Adi; Lucci, Anthony; Prieto, Victor G; Davies, Michael A; Allison, James P; Sharma, Padmanee; Wargo, Jennifer A; Ariyan, Charlotte; Tawbi, Hussein A.

Nature ; 615(7953): E23, 2023 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-36894629

10.

TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion.

Sharma, Naveen; Vacher, Jean; Allison, James P.

Proc Natl Acad Sci U S A ; 116(21): 10453-10462, 2019 05 21.

Artigo em Inglês | MEDLINE | ID: mdl-31076558

11.

Autoimmune antibodies correlate with immune checkpoint therapy-induced toxicities.

Tahir, Salahaldin A; Gao, Jianjun; Miura, Yuji; Blando, Jorge; Tidwell, Rebecca S S; Zhao, Hao; Subudhi, Sumit K; Tawbi, Hussein; Keung, Emily; Wargo, Jennifer; Allison, James P; Sharma, Padmanee.

Proc Natl Acad Sci U S A ; 116(44): 22246-22251, 2019 10 29.

Artigo em Inglês | MEDLINE | ID: mdl-31611368

12.

Combination anti-CTLA-4 plus anti-PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies.

Wei, Spencer C; Anang, Nana-Ama A S; Sharma, Roshan; Andrews, Miles C; Reuben, Alexandre; Levine, Jacob H; Cogdill, Alexandria P; Mancuso, James J; Wargo, Jennifer A; Pe'er, Dana; Allison, James P.

Proc Natl Acad Sci U S A ; 116(45): 22699-22709, 2019 11 05.

Artigo em Inglês | MEDLINE | ID: mdl-31636208

13.

Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer.

Blando, Jorge; Sharma, Anu; Higa, Maria Gisela; Zhao, Hao; Vence, Luis; Yadav, Shalini S; Kim, Jiseong; Sepulveda, Alejandro M; Sharp, Michael; Maitra, Anirban; Wargo, Jennifer; Tetzlaff, Michael; Broaddus, Russell; Katz, Matthew H G; Varadhachary, Gauri R; Overman, Michael; Wang, Huamin; Yee, Cassian; Bernatchez, Chantale; Iacobuzio-Donahue, Christine; Basu, Sreyashi; Allison, James P; Sharma, Padmanee.

Proc Natl Acad Sci U S A ; 116(5): 1692-1697, 2019 01 29.

Artigo em Inglês | MEDLINE | ID: mdl-30635425

14.

T cell surveillance of oncogene-induced prostate cancer is impeded by T cell-derived TGF-ß1 cytokine.

Donkor, Moses K; Sarkar, Abira; Savage, Peter A; Franklin, Ruth A; Johnson, Linda K; Jungbluth, Achim A; Allison, James P; Li, Ming O.

Immunity ; 35(1): 123-34, 2011 Jul 22.

Artigo em Inglês | MEDLINE | ID: mdl-21757379

15.

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.

Gubin, Matthew M; Zhang, Xiuli; Schuster, Heiko; Caron, Etienne; Ward, Jeffrey P; Noguchi, Takuro; Ivanova, Yulia; Hundal, Jasreet; Arthur, Cora D; Krebber, Willem-Jan; Mulder, Gwenn E; Toebes, Mireille; Vesely, Matthew D; Lam, Samuel S K; Korman, Alan J; Allison, James P; Freeman, Gordon J; Sharpe, Arlene H; Pearce, Erika L; Schumacher, Ton N; Aebersold, Ruedi; Rammensee, Hans-Georg; Melief, Cornelis J M; Mardis, Elaine R; Gillanders, William E; Artyomov, Maxim N; Schreiber, Robert D.

Nature ; 515(7528): 577-81, 2014 Nov 27.

Artigo em Inglês | MEDLINE | ID: mdl-25428507

16.

The distribution of T-cell subsets and the expression of immune checkpoint receptors and ligands in patients with newly diagnosed and relapsed acute myeloid leukemia.

Williams, Patrick; Basu, Sreyashi; Garcia-Manero, Guillermo; Hourigan, Christopher S; Oetjen, Karolyn A; Cortes, Jorge E; Ravandi, Farhad; Jabbour, Elias J; Al-Hamal, Zainab; Konopleva, Marina; Ning, Jing; Xiao, Lianchun; Hidalgo Lopez, Juliana; Kornblau, Steve M; Andreeff, Michael; Flores, Wilmer; Bueso-Ramos, Carlos; Blando, Jorge; Galera, Pallavi; Calvo, Katherine R; Al-Atrash, Gheath; Allison, James P; Kantarjian, Hagop M; Sharma, Padmanee; Daver, Naval G.

Cancer ; 125(9): 1470-1481, 2019 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-30500073

17.

Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity.

Nawaf, Maher G; Ulvmar, Maria H; Withers, David R; McConnell, Fiona M; Gaspal, Fabrina M; Webb, Gwilym J; Jones, Nick D; Yagita, Hideo; Allison, James P; Lane, Peter J L.

J Immunol ; 199(3): 974-981, 2017 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-28646041

18.

Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities.

Subudhi, Sumit K; Aparicio, Ana; Gao, Jianjun; Zurita, Amado J; Araujo, John C; Logothetis, Christopher J; Tahir, Salahaldin A; Korivi, Brinda R; Slack, Rebecca S; Vence, Luis; Emerson, Ryan O; Yusko, Erik; Vignali, Marissa; Robins, Harlan S; Sun, Jingjing; Allison, James P; Sharma, Padmanee.

Proc Natl Acad Sci U S A ; 113(42): 11919-11924, 2016 10 18.

Artigo em Inglês | MEDLINE | ID: mdl-27698113

19.

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting.

Matsushita, Hirokazu; Vesely, Matthew D; Koboldt, Daniel C; Rickert, Charles G; Uppaluri, Ravindra; Magrini, Vincent J; Arthur, Cora D; White, J Michael; Chen, Yee-Shiuan; Shea, Lauren K; Hundal, Jasreet; Wendl, Michael C; Demeter, Ryan; Wylie, Todd; Allison, James P; Smyth, Mark J; Old, Lloyd J; Mardis, Elaine R; Schreiber, Robert D.

Nature ; 482(7385): 400-4, 2012 Feb 08.

Artigo em Inglês | MEDLINE | ID: mdl-22318521

20.

Unique potential of 4-1BB agonist antibody to promote durable regression of HPV+ tumors when combined with an E6/E7 peptide vaccine.

Bartkowiak, Todd; Singh, Shailbala; Yang, Guojun; Galvan, Gloria; Haria, Dhwani; Ai, Midan; Allison, James P; Sastry, K Jagannadha; Curran, Michael A.

Proc Natl Acad Sci U S A ; 112(38): E5290-9, 2015 Sep 22.

Artigo em Inglês | MEDLINE | ID: mdl-26351680

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