Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.

Dolton, Garry; Rius, Cristina; Wall, Aaron; Szomolay, Barbara; Bianchi, Valentina; Galloway, Sarah A E; Hasan, Md Samiul; Morin, Théo; Caillaud, Marine E; Thomas, Hannah L; Theaker, Sarah; Tan, Li Rong; Fuller, Anna; Topley, Katie; Legut, Mateusz; Attaf, Meriem; Hopkins, Jade R; Behiry, Enas; Zabkiewicz, Joanna; Alvares, Caroline; Lloyd, Angharad; Rogers, Amber; Henley, Peter; Fegan, Christopher; Ottmann, Oliver; Man, Stephen; Crowther, Michael D; Donia, Marco; Svane, Inge Marie; Cole, David K; Brown, Paul E; Rizkallah, Pierre; Sewell, Andrew K.

Cell ; 186(16): 3333-3349.e27, 2023 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-37490916

2.

Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation.

Chiriches, Claudia; Nicolaisen, Nathalie; Wieske, Maria; Elhaddad, Heba; Mehmetbeyoglu, Ecmel; Alvares, Caroline; Becher, Dörte; Hole, Paul; Ottmann, Oliver Gerhard; Ruthardt, Martin.

PLoS Genet ; 18(10): e1010463, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36288392

3.

A phase 1b study of venetoclax and alvocidib in patients with relapsed/refractory acute myeloid leukemia.

Jonas, Brian A; Hou, Jing-Zhou; Roboz, Gail J; Alvares, Caroline L; Jeyakumar, Deepa; Edwards, John R; Erba, Harry P; Kelly, Richard J; Röllig, Christoph; Fiedler, Walter; Brackman, Deanna; Siddani, Satya R; Chyla, Brenda; Hilger-Rolfe, Jacqueline; Watts, Justin M.

Hematol Oncol ; 41(4): 743-752, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37086447

4.

Combination of a mitogen-activated protein kinase inhibitor with the tyrosine kinase inhibitor pacritinib combats cell adhesion-based residual disease and prevents re-expansion of FLT3-ITD acute myeloid leukaemia.

Zabkiewicz, Joanna; Lazenby, Michelle; Edwards, Gareth; Bygrave, Ceri A; Omidvar, Nader; Zhuang, Lihui; Knapper, Steve; Guy, Carol; Hills, Robert K; Burnett, Alan K; Alvares, Caroline L.

Br J Haematol ; 191(2): 231-242, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32394450

5.

Successful molecular targeted treatment of AML in pregnancy with Azacitidine and Sorafenib with no adverse fetal outcomes.

Mahdi, Ali J; Gosrani, Deepan; Chakraborty, Mallinath; Rees, Alexandra; Conner, Christine; Wilson, Keith; Rayment, Rachel; Alvares, Caroline.

Br J Haematol ; 180(4): 603-604, 2018 02.

Artigo em Inglês | MEDLINE | ID: mdl-27766617

6.

CNL and aCML should be considered as a single entity based on molecular profiles and outcomes.

Carreño-Tarragona, Gonzalo; Álvarez-Larrán, Alberto; Harrison, Claire; Martínez-Ávila, José Carlos; Hernández-Boluda, Juan Carlos; Ferrer-Marín, Francisca; Radia, Deepti H; Mora, Elvira; Francis, Sebastian; González-Martínez, Teresa; Goddard, Kathryn; Pérez-Encinas, Manuel; Narayanan, Srinivasan; Raya, José María; Singh, Vikram; Gutiérrez, Xabier; Toth, Peter; Amat-Martínez, Paula; Mcilwaine, Louisa; Alobaidi, Magda; Mayani, Karan; McGregor, Andrew; Stuckey, Ruth; Psaila, Bethan; Segura, Adrián; Alvares, Caroline; Davidson, Kerri; Osorio, Santiago; Cutting, Robert; Sweeney, Caroline P; Rufián, Laura; Moreno, Laura; Cuenca, Isabel; Smith, Jeffery; Morales, María Luz; Gil-Manso, Rodrigo; Koutsavlis, Ioannis; Wang, Lihui; Mead, Adam J; Rozman, María; Martínez-López, Joaquín; Ayala, Rosa; Cross, Nicholas C P.

Blood Adv ; 7(9): 1672-1681, 2023 05 09.

Artigo em Inglês | MEDLINE | ID: mdl-36375042

7.

Tyrosine kinase inhibitor insensitivity of non-cycling CD34+ human acute myeloid leukaemia cells with FMS-like tyrosine kinase 3 mutations.

Alvares, Caroline L; Schenk, Tino; Hulkki, Sanna; Min, Toon; Vijayaraghavan, Gowri; Yeung, Jenny; Gonzalez, David; So, Chi W E; Greaves, Mel; Titley, Ian; Bartolovic, Kerol; Morgan, Gareth.

Br J Haematol ; 154(4): 457-65, 2011 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-21689085

8.

The role of second autografts in the management of myeloma at first relapse.

Alvares, Caroline L; Davies, Faith E; Horton, Clive; Patel, Gita; Powles, Ray; Morgan, Gareth J.

Haematologica ; 91(1): 141-2, 2006 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-16434386

9.

The combination of cyclophosphomide, thalidomide and dexamethasone is an effective alternative to cyclophosphamide - vincristine - doxorubicin - methylprednisolone as induction chemotherapy prior to autologous transplantation for multiple myeloma: a case-matched analysis.

Wu, Ping; Davies, Faith E; Horton, Clive; Jenner, Matthew W; Krishnan, Biju; Alvares, Caroline L; Saso, Radovan; McCormack, Rita; Dines, Sharon; Treleaven, Jennifer G; Potter, Michael N; Ethell, Mark E; Morgan, Gareth J.

Leuk Lymphoma ; 47(11): 2335-8, 2006 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-17107906

10.

Benzene and the hemopoietic stem cell.

Morgan, Gareth J; Alvares, Caroline L.

Chem Biol Interact ; 153-154: 217-22, 2005 May 30.

Artigo em Inglês | MEDLINE | ID: mdl-15935819

11.

Isolated bone marrow involvement in diffuse large B cell lymphoma: a report of three cases with review of morphological, immunophenotypic and cytogenetic findings.

Alvares, Caroline L; Matutes, Estella; Scully, Marie A; Swansbury, John; Min, Toon; Gruszka-Westwood, Alicja M; Atkinson, Shayne; Hilditch, Benjamin; Morilla, Ricardo; Wotherspoon, Andrew C; Catovsky, Daniel.

Leuk Lymphoma ; 45(4): 769-75, 2004 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-15160954

12.

Long-term outcomes of previously untreated myeloma patients: responses to induction chemotherapy and high-dose melphalan incorporated within a risk stratification model can help to direct the use of novel treatments.

Alvares, Caroline L; Davies, Faith E; Horton, Clive; Patel, Gita; Powles, Ray; Sirohi, Bhawna; Zuha, Roslin; Gatt, Alex; Saso, Radovan; Treleaven, Jennifer G; Dearden, Claire E; Potter, Michael N; Ethell, Mark E; Morgan, Gareth J.

Br J Haematol ; 129(5): 607-14, 2005 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-15916682

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