Detalhe da pesquisa
1.
An exonuclease-resistant chain-terminating nucleotide analogue targeting the SARS-CoV-2 replicase complex.
Nucleic Acids Res
; 52(3): 1325-1340, 2024 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096103
2.
Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions.
Org Biomol Chem
; 13(45): 11052-71, 2015 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26394794
3.
Biophysical and structural study of La Crosse virus endonuclease inhibition for the development of new antiviral options.
IUCrJ
; 11(Pt 3): 374-383, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38656310
4.
Macro1 domain residue F156: A hallmark of SARS-CoV-2 de-MARylation specificity.
Virology
; 587: 109845, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37517331
5.
AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5.
Antiviral Res
; 212: 105574, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36905944
6.
Inhibition of Arenaviridae nucleoprotein exonuclease by bisphosphonate.
IUCrJ
; 9(Pt 4): 468-479, 2022 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35844481
7.
Identification of potent inhibitors of arenavirus and SARS-CoV-2 exoribonucleases by fluorescence polarization assay.
Antiviral Res
; 204: 105364, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35716929
8.
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.
Nat Commun
; 13(1): 621, 2022 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35110538
9.
Observation of arenavirus nucleoprotein heptamer assembly.
FEBS Open Bio
; 11(4): 1076-1083, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33534950
10.
Biochemical characterization of the (nucleoside-2'O)-methyltransferase activity of dengue virus protein NS5 using purified capped RNA oligonucleotides (7Me)GpppAC(n) and GpppAC(n).
J Gen Virol
; 91(Pt 1): 112-21, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19776234
11.
Brothers in Arms: Structure, Assembly and Function of Arenaviridae Nucleoprotein.
Viruses
; 12(7)2020 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32708976
12.
Discovery, SAR study and ADME properties of methyl 4-amino-3-cyano-1-(2-benzyloxyphenyl)-1H-pyrazole-5-carboxylate as an HIV-1 replication inhibitor.
RSC Med Chem
; 11(5): 577-582, 2020 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479659
13.
Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites.
Antiviral Res
; 178: 104793, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283108
14.
Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity.
J Virol
; 82(16): 8071-84, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18417574
15.
Identification of a new natural gastric lipase inhibitor from star anise.
Food Funct
; 10(1): 469-478, 2019 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30632597
16.
Metal chelators for the inhibition of the lymphocytic choriomeningitis virus endonuclease domain.
Antiviral Res
; 162: 79-89, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30557576
17.
Gln151 of HIV-1 reverse transcriptase acts as a steric gate towards clinically relevant acyclic phosphonate nucleotide analogues.
Antivir Ther
; 13(1): 115-24, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18389906
18.
The flavivirus polymerase as a target for drug discovery.
Antiviral Res
; 80(1): 23-35, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18611413
19.
Synthesis and substrate properties towards HIV-1 reverse transcriptase of new diphosphate analogues of 9-[(2-phosphonomethoxy)ethyl]adenine.
Antivir Chem Chemother
; 26: 2040206618757636, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29436843
20.
How to Control HTLV-1-Associated Diseases: Preventing de Novo Cellular Infection Using Antiviral Therapy.
Front Microbiol
; 9: 278, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29593659