Detalhe da pesquisa
1.
An in Vitro Assay Using Cultured Kupffer Cells Can Predict the Impact of Drug Conjugation on in Vivo Antibody Pharmacokinetics.
Mol Pharm
; 17(3): 802-809, 2020 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31976667
2.
Development of orally active inhibitors of protein and cellular fucosylation.
Proc Natl Acad Sci U S A
; 110(14): 5404-9, 2013 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23493549
3.
Brentuximab Vedotin-Driven Microtubule Disruption Results in Endoplasmic Reticulum Stress Leading to Immunogenic Cell Death and Antitumor Immunity.
Mol Cancer Ther
; 23(1): 68-83, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37775098
4.
Improving Antibody-Tubulysin Conjugates through Linker Chemistry and Site-Specific Conjugation.
ChemMedChem
; 16(7): 1077-1081, 2021 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33369163
5.
Novel peptide linkers for highly potent antibody-auristatin conjugate.
Bioconjug Chem
; 19(10): 1960-3, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18803412
6.
Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody-Drug Conjugates.
Mol Cancer Ther
; 17(12): 2633-2642, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30242091
7.
Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia.
Mol Cancer Ther
; 17(2): 554-564, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29142066
8.
Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody-Drug Conjugates.
Mol Cancer Ther
; 16(1): 116-123, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28062707
9.
Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index.
Nat Biotechnol
; 33(7): 733-5, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26076429
10.
SGN-LIV1A: a novel antibody-drug conjugate targeting LIV-1 for the treatment of metastatic breast cancer.
Mol Cancer Ther
; 13(12): 2991-3000, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25253783
11.
Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates.
Nat Biotechnol
; 32(10): 1059-62, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25194818