Detalhe da pesquisa
1.
Strategies for calibrating models of biology.
Brief Bioinform
; 21(1): 24-35, 2020 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30239570
2.
Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat.
J Pharmacol Exp Ther
; 371(2): 476-486, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31110114
3.
Utilising a simulation platform to understand the effect of domain model assumptions.
Nat Comput
; 14(1): 99-107, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25722664
4.
Spartan: a comprehensive tool for understanding uncertainty in simulations of biological systems.
PLoS Comput Biol
; 9(2): e1002916, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23468606
5.
In silico investigation into dendritic cell regulation of CD8Treg mediated killing of Th1 cells in murine experimental autoimmune encephalomyelitis.
BMC Bioinformatics
; 14 Suppl 6: S9, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23734666
6.
Development of a homogeneous AlphaLISA ubiquitination assay using ubiquitin binding matrices as universal components for the detection of ubiquitinated proteins.
Biochim Biophys Acta
; 1823(11): 2038-45, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22504171
7.
Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
J Biol Chem
; 286(48): 41530-41538, 2011 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21987572
8.
Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors.
Bioorg Med Chem Lett
; 22(15): 4967-74, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22765895
9.
Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis.
Nat Cell Biol
; 4(6): 451-6, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12021772
10.
Discovery of triazine-benzimidazoles as selective inhibitors of mTOR.
Bioorg Med Chem Lett
; 21(7): 2064-70, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21376583
11.
Macrophage Transactivation for Chemokine Production Identified as a Negative Regulator of Granulomatous Inflammation Using Agent-Based Modeling.
Front Immunol
; 9: 637, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29636754
12.
Extending and Applying Spartan to Perform Temporal Sensitivity Analyses for Predicting Changes in Influential Biological Pathways in Computational Models.
IEEE/ACM Trans Comput Biol Bioinform
; 14(2): 431-442, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-26887007
13.
Assays for RING family ubiquitin ligases.
Methods Mol Biol
; 301: 37-46, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15917624
14.
Using argument notation to engineer biological simulations with increased confidence.
J R Soc Interface
; 12(104): 20141059, 2015 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25589574
15.
Modelling biological behaviours with the unified modelling language: an immunological case study and critique.
J R Soc Interface
; 11(99)2014 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25142524
16.
Functional complexity of the Leishmania granuloma and the potential of in silico modeling.
Front Immunol
; 4: 35, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23423646
17.
In silico investigation of novel biological pathways: the role of CD200 in regulation of T cell priming in experimental autoimmune encephalomyelitis.
Biosystems
; 112(2): 107-21, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23499816
18.
Determining disease intervention strategies using spatially resolved simulations.
PLoS One
; 8(11): e80506, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24244694
19.
Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.
J Med Chem
; 56(11): 4320-42, 2013 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23701517
20.
Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
J Med Chem
; 56(24): 10003-15, 2013 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24294969