Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Safety and activity of anti-CD14 antibody IC14 (atibuclimab) in ALS: Experience with expanded access protocol.

Gelevski, Dario; Addy, Grace; Rohrer, Margot; Cohen, Caroline; Roderick, Aimee; Winter, Allison; Carey, Judith; Scalia, Jennifer; Yerton, Megan; Weber, Harli; Doyle, Michael; Parikh, Neil; Kane, Geli; Ellrodt, Amy; Burke, Katherine; D'Agostino, Derek; Sinani, Ervin; Yu, Hong; Sherman, Alexander; Agosti, Jan; Redlich, Garry; Charmley, Patrick; Crowe, David; Appleby, Mark; Ziegelaar, Brian; Hanus, Katherine; Li, Zhenhua; Babu, Suma; Nicholson, Katharine; Luppino, Sarah; Berry, James; Baecher-Allan, Clare; Paganoni, Sabrina; Cudkowicz, Merit.

Muscle Nerve ; 67(5): 354-362, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-36533976

2.

Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development.

Park, Heon; Staehling, Karen; Tsang, Mark; Appleby, Mark W; Brunkow, Mary E; Margineantu, Daciana; Hockenbery, David M; Habib, Tania; Liggitt, H Denny; Carlson, George; Iritani, Brian M.

Immunity ; 36(5): 769-81, 2012 May 25.

Artigo em Inglês | MEDLINE | ID: mdl-22608497

3.

A forward-genetic approach for analysis of the immune system.

Appleby, Mark W; Ramsdell, Fred.

Nat Rev Immunol ; 3(6): 463-71, 2003 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-12776206

4.

Phase 1b dose-escalation, safety, and pharmacokinetic study of IC14, a monoclonal antibody against CD14, for the treatment of amyotrophic lateral sclerosis.

Henderson, Robert D; Agosti, Jan M; McCombe, Pamela A; Thorpe, Kathryn; Heggie, Susan; Heshmat, Saman; Appleby, Mark W; Ziegelaar, Brian W; Crowe, David T; Redlich, Garry L.

Medicine (Baltimore) ; 100(42): e27421, 2021 Oct 22.

Artigo em Inglês | MEDLINE | ID: mdl-34678870

5.

Importance of the TIMI frame count: implications for future trials.

Appleby, Mark A; Michaels, Andrew D; Chen, Michael; Michael, C Gibson.

Curr Control Trials Cardiovasc Med ; 1(1): 31-34, 2000.

Artigo em Inglês | MEDLINE | ID: mdl-11714404

6.

Pretreatment with intragraft verapamil prior to percutaneous coronary intervention of saphenous vein graft lesions: results of the randomized, controlled vasodilator prevention on no-reflow (VAPOR) trial.

Michaels, Andrew D; Appleby, Mark; Otten, Matthew H; Dauterman, Kent; Ports, Thomas A; Chou, Tony M; Gibson, C Michael.

J Invasive Cardiol ; 14(6): 299-302, 2002 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-12042618

7.

Engineering of stable bispecific antibodies targeting IL-17A and IL-23.

Mabry, Robert; Lewis, Katherine E; Moore, Margaret; McKernan, Patricia A; Bukowski, Thomas R; Bontadelli, Kristen; Brender, Ty; Okada, Shannon; Lum, Karen; West, James; Kuijper, Joseph L; Ardourel, Dan; Franke, Secil; Lockwood, Luann; Vu, Tuyen; Frank, Amanda; Appleby, Mark W; Wolf, Anitra; Reardon, Brian; Hamacher, Nels B; Stevens, Brenda; Lewis, Patsy; Lewis, Kenneth B; Gilbertson, Debra G; Lantry, Megan; Julien, Susan H; Ostrander, Craig; Chan, Chung; Byrnes-Blake, Kelly; Brody, Jennifer; Presnell, Scott; Meengs, Brent; Levin, Steven D; Snavely, Mark.

Protein Eng Des Sel ; 23(3): 115-27, 2010 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-20022918

8.

Key developments in cardiovascular medicine.

Appleby, Mark A; Hall, Alistair.

Practitioner ; 246(1635): 375-7, 380-2, 2002 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-12073696

9.

CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance.

Friedline, Randall H; Brown, David S; Nguyen, Hai; Kornfeld, Hardy; Lee, Jinhee; Zhang, Yi; Appleby, Mark; Der, Sandy D; Kang, Joonsoo; Chambers, Cynthia A.

J Exp Med ; 206(2): 421-34, 2009 Feb 16.

Artigo em Inglês | MEDLINE | ID: mdl-19188497

10.

A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic protein 1 in lymphopoiesis and innate immunity.

Park, Heon; Staehling-Hampton, Karen; Appleby, Mark W; Brunkow, Mary E; Habib, Tania; Zhang, Yi; Ramsdell, Fred; Liggitt, H Denny; Freie, Brian; Tsang, Mark; Carlson, George; Friend, Sherree; Frevert, Charles; Iritani, Brian M.

J Exp Med ; 205(12): 2899-913, 2008 Nov 24.

Artigo em Inglês | MEDLINE | ID: mdl-19015308

11.

Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F.

Kuestner, Rolf E; Taft, David W; Haran, Aaron; Brandt, Cameron S; Brender, Ty; Lum, Karen; Harder, Brandon; Okada, Shannon; Ostrander, Craig D; Kreindler, James L; Aujla, Shean J; Reardon, Brian; Moore, Margaret; Shea, Pamela; Schreckhise, Randall; Bukowski, Thomas R; Presnell, Scott; Guerra-Lewis, Patricia; Parrish-Novak, Julia; Ellsworth, Jeff L; Jaspers, Stephen; Lewis, Katherine E; Appleby, Mark; Kolls, Jay K; Rixon, Mark; West, James W; Gao, Zeren; Levin, Steven D.

J Immunol ; 179(8): 5462-73, 2007 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-17911633

12.

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist.

Winkler, David G; Sutherland, May Kung; Geoghegan, James C; Yu, Changpu; Hayes, Trenton; Skonier, John E; Shpektor, Diana; Jonas, Mechtild; Kovacevich, Brian R; Staehling-Hampton, Karen; Appleby, Mark; Brunkow, Mary E; Latham, John A.

EMBO J ; 22(23): 6267-76, 2003 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-14633986

13.

A novel mutation in CD83 results in the development of a unique population of CD4+ T cells.

García-Martínez, Leon F; Appleby, Mark W; Staehling-Hampton, Karen; Andrews, Dawn M; Chen, Yuching; McEuen, Mark; Tang, Phuong; Rhinehart, Rebecca L; Proll, Sean; Paeper, Bryan; Brunkow, Mary E; Grandea, Andres G; Howard, Edward D; Walker, Don E; Charmley, Patrick; Jonas, Mechthild; Shaw, Stevan; Latham, John A; Ramsdell, Fred.

J Immunol ; 173(5): 2995-3001, 2004 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-15322158

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