RESUMO
BACKGROUND: The high frequency of suicide risk in adolescents necessitates the development and validation of specific tools for systematic screening. To date, there are translated, but not validated suicide risk screening tools in Spanish. OBJECTIVE: To validate the Spanish version of the Ask Suicide-Screening Questions (ASQ) for suicide risk screening in pediatric patients in Argentina. METHOD: Using a cross-sectional multicenter design, a convenience sample of pediatric patients aged 10 to 18 years old were recruited from outpatient/inpatient medical settings and private psychiatric clinics. The Spanish version of the Suicidal Ideation Questionnaire (SIQ) assessment tool was used as a standard criterion to validate the ASQ. RESULTS: A total of 301/380 pediatric patients were screened for suicide risk. Twentyeight percent of the entire sample (83/301) of youth screened positive on the ASQ, and 21% (62/301) screened positive on the SIQ/SIQ-JR and were considered "at risk" for suicide. Compared with the SIQ, the Spanish ASQ yielded a sensitivity of 96.8% (95% Confidence Interval [CI]: 88.8-99.6%), specificity of 90.4% (95% CI: 85.9-93.8%), positive predictive value of 72.3% (95 CI: 61.4-81.6%), and negative predictive value of 99.1% (95% CI: 96.7-99.9%). The positive Likelihood Ratio (LR) was 10.1 (95% CI: 6.1-14.0), and the negative LR was 0.03 (95% CI: -0.01-0.09). Kappa was 0.77 (95% CI: 0.69-0.86), and the Area Under the Curve was 0.94 (95% CI: 0.91-0.97). CONCLUSION: The Spanish language ASQ demonstrated strong psychometric properties, providing initial evidence that it is a valid tool for identifying Spanish-speaking youth at risk for suicide.
Assuntos
Suicídio , Adolescente , Humanos , Criança , Estudos Transversais , Argentina , Pacientes Internados , Pacientes Ambulatoriais , Programas de Rastreamento , Ideação Suicida , Inquéritos e QuestionáriosRESUMO
In rodents, neuronal plasticity decreases and spatial learning and working memory deficits increase upon aging. Several authors have shown that rats reared in enriched environments have better cognitive performance in association with increased neuronal plasticity than animals reared in standard environments. We hypothesized that enriched environment could preserve animals from the age-associated neurological impairments, mainly through NO-dependent mechanisms of induction of neuronal plasticity. We present evidence that 27 months old rats from an enriched environment show a better performance in spatial working memory than standard reared rats of the same age. Both mtNOS and cytosolic nNOS activities were found significantly increased (73% and 155%, respectively) in female rats from enriched environment as compared with control animals kept in a standard environment. The enzymatic activity of complex I was 80% increased in rats from enriched environment as compared with control rats. We conclude that an extensively enriched environment prevents old rats from the aging-associated impairment of spatial cognition, synaptic plasticity and nitric oxide production.
Assuntos
Envelhecimento/fisiologia , Cognição/fisiologia , Óxido Nítrico/biossíntese , Sinapses/fisiologia , Animais , Encéfalo/enzimologia , Encéfalo/fisiologia , Óxido Nítrico Sintase/fisiologia , Estresse Oxidativo/fisiologia , RatosRESUMO
Most languages have a basic or "canonical" word order, which determines the relative positions of the subject (S), the verb (V), and the object (O) in a typical declarative sentence. The frequency of occurrence of the six possible word orders among world languages is not distributed uniformly. While SVO and SOV represent around 85% of world languages, orders like VSO (9%) or OSV (0.5%) are much less frequent or extremely rare. One possible explanation for this asymmetry is that biological and cognitive constraints for structured sequence processing make some word orders easier to be processed than others. Therefore, the high frequency of these word orders would be related to their higher learnability. The aim of the present study was to compare the learnability of different word orders between groups of adult subjects. Four artificial languages with different word orders were trained: two frequent (SVO, SOV) and two infrequent (VSO, OSV). In a test stage, subjects were asked to discriminate between new correct sentences and syntax or semantic violations. Higher performance rates and faster responses were observed for more frequent word orders. The results support the hypothesis that more frequent word orders are more easily learned.
Assuntos
Idioma , Aprendizagem/fisiologia , Semântica , Adolescente , Adulto , Feminino , Humanos , Linguística , Masculino , LeituraRESUMO
El objetivo del presente trabajo es exponer una breve revisión del estudio del razonamiento analógico desde la Teoría de los Marcos Relacionales (TMR), considerando los modelos formulados hasta la actualidad y la exploración experimental. A sua vez, se abordará el estudio del desarrollo del razonamiento analógico en la infancia, surgido en el marco de las controversias generadas por los distintos enfoques de la psicología. Se expondrán los hallazgos obtenidos utilizando métodos de imágenes cerebrales desde las ciencias cognitivas. Finalmente se comentarán las posibles aplicaciones de este paradigma. Los estudios revisados acerca del razonamiento analógico desde la TMR proveen relevante evidencia empírica, principalmente en el ámbito de la evaluación y sugieren ventajas de este paradigma en comparación con aproximaciones cognitivistas. A su vez, se propone su implementación como instrumento de entrenamiento cognitivo. En conclusión, la TMR propone un modelo útil al estudio del razonamiento analógico desde la perspectiva del análisis del comportamiento.
The main goal of the present work is to summarize the Relational Frame Theory (RFT) account of analogical reasoning, reviewing theoretical models and experimental studies published so far. Additionally, developmental studies of analogical reasoning during childhood will be addressed, considering the alternative hypothesis and controversies between different psychological theories. Findings from cognitive studies using neuroimaging techniques will also be discussed. Finally, the potential applications of the paradigm will be considered. The studies reviewed about analogical reasoning from the RFT provide relevant empirical evidence, mainly in the field of assessment and suggest advantages of this paradigm compared to cognitivist approaches. In turn, its implementation is proposed as a tool for cognitive training. In conclusion, the RFT offers a useful model to study analogical reasoning from the behavior analysis perspective.
RESUMO
En este trabajo se utilizó una gramática artificial, consistente en una serie de reglas que especifican posibles órdenes de secuencias de letras, para evaluar la capacidad de transferencia de los sujetos, esto es la extracción de estas reglas y su aplicación a patrones de letras novedosas. Para ello 57 sujetos se asignaron aleatoriamente a dos formas de entrenamiento: una estándar donde debían memorizar y transcribir las secuencias correctas (gramaticales), y otra donde debían discriminar por ensayo y error entre secuencias correctas e incorrectas (no gramaticales) mediante un procedimiento de realimentación. Con esta forma de entrenamiento se obtuvieron desempeños significativamente mejores que con el procedimiento estándar. Se discuten los resultados en el contexto de la aplicación de las gramáticas artificiales como paradigma experimental para el estudio de los procesos subyacentes a la adquisición del lenguaje.
In this work an artificial grammar has been used, which consists in a set of rules that specifies possible orders of strings of letters, to evaluate subjects ability to transfer the extracted rules and implement these to patterns of novel letters. 57 subjects were randomly assigned to two learning procedures: a standard one in which they had to memorize and transcribe the correct (grammatical) sequences, and one in which they had to discriminate between correct and incorrect (ungrammatical) sequences by use of a feedback procedure. Subjects trained with the feedback procedure had a significantly better performance than subjects trained with the standard one. These results are discussed in the context of the implementation of artificial grammar as an experimental paradigm for studying processes underlying language acquisition.
RESUMO
Varios estudios han abordado cómo las instrucciones compiten con contingencias de reforzamiento para controlar conductas complejas, pero no se ha estudiado cabalmente cómo el control instruccional afecta a conductas derivadas, no explícitamente entrenadas. Este estudio intentó determinar si las instrucciones ejercen mayor control que las consecuencias diferenciales de respuesta sobre conductas derivadas, en sintonía con la literatura sobre insensibilidad a las contingencias. Cuarenta y seis participantes realizaron una tarea de emparejamiento con la muestra, analizándose su preferencia para derivar relaciones de equivalencia entre estímulos que fueron vinculados de dos maneras contradictorias, una por instrucciones y otra por consecuencias diferenciales. Se observó una mayor eficacia del método de entrenamiento por instrucciones para aprender relaciones condicionales entre estímulos. Por otro lado, se constató una significativa prevalencia para formar relaciones de equivalencia de aquello aprendido previamente por instrucciones, aunque este aspecto podría estar vinculado a la mayor eficacia en el aprendizaje de los contenidos previos...