Detalhe da pesquisa
1.
Regulation of extracellular progranulin in medial prefrontal cortex.
Neurobiol Dis
; 188: 106326, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37838007
2.
Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia.
J Transl Med
; 21(1): 387, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37322482
3.
Delivering progranulin to neuronal lysosomes protects against excitotoxicity.
J Biol Chem
; 297(3): 100993, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34298019
4.
Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions.
Neurobiol Dis
; 134: 104708, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31837424
5.
Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis.
J Neurosci
; 38(9): 2341-2358, 2018 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378861
6.
Reduction of microglial progranulin does not exacerbate pathology or behavioral deficits in neuronal progranulin-insufficient mice.
Neurobiol Dis
; 124: 152-162, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30448285
7.
Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia.
Brain
; 140(5): 1447-1465, 2017 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379303
8.
Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration.
J Neurosci
; 36(4): 1316-23, 2016 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26818518
9.
Dietary manipulation of serotonergic and dopaminergic function in C57BL/6J mice with amino acid depletion mixtures.
J Neural Transm (Vienna)
; 121(2): 153-62, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24061481
10.
Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations.
Acta Neuropathol Commun
; 11(1): 70, 2023 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37118844
11.
Dopamine uptake inhibitors but not dopamine releasers induce greater increases in motor behavior and extracellular dopamine in adolescent rats than in adult male rats.
J Pharmacol Exp Ther
; 335(1): 124-32, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20605908
12.
Elevated levels of extracellular vesicles in progranulin-deficient mice and FTD-GRN Patients.
Ann Clin Transl Neurol
; 7(12): 2433-2449, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33197149
13.
Impaired ß-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations.
Acta Neuropathol Commun
; 7(1): 218, 2019 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31870439
14.
Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency.
Mol Neurodegener
; 13(1): 32, 2018 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29929528
15.
Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice.
eNeuro
; 2(3)2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26361634
16.
Simplified dietary acute tryptophan depletion: effects of a novel amino acid mixture on the neurochemistry of C57BL/6J mice.
Food Nutr Res
; 59: 27424, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26278978
17.
MicroRNA-124 modulates social behavior in frontotemporal dementia.
Nat Med
; 20(12): 1381-3, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25473917
18.
Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans.
PLoS One
; 9(12): e114459, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25486066
19.
Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.
J Exp Med
; 211(10): 1937-45, 2014 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25155018
20.
Adolescent male rats are less sensitive than adults to the anxiogenic and serotonin-releasing effects of fenfluramine.
Neuropharmacology
; 65: 213-22, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23103347