Detalhe da pesquisa
1.
Secreted histidyl-tRNA synthetase splice variants elaborate major epitopes for autoantibodies in inflammatory myositis.
J Biol Chem
; 289(28): 19269-75, 2014 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24898250
2.
Therapeutics development for cystic fibrosis: a successful model for a multisystem genetic disease.
Annu Rev Med
; 62: 107-25, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21226613
3.
Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation.
N Engl J Med
; 363(21): 1991-2003, 2010 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21083385
4.
Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.
Thorax
; 67(1): 12-8, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21825083
5.
A pipeline of therapies for cystic fibrosis.
Semin Respir Crit Care Med
; 30(5): 611-26, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19760548
6.
Sweat chloride as a biomarker of CFTR activity: proof of concept and ivacaftor clinical trial data.
J Cyst Fibros
; 13(2): 139-47, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24660233
7.
Multicenter intestinal current measurements in rectal biopsies from CF and non-CF subjects to monitor CFTR function.
PLoS One
; 8(9): e73905, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24040112