Detalhe da pesquisa
1.
Circulating androgens and SHBG during the normal menstrual cycle in two ethnic populations.
Scand J Clin Lab Invest
; 77(3): 184-189, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28276724
2.
A novel oral insulin-like growth factor-1 receptor pathway modulator and its implications for patients with non-small cell lung carcinoma: A phase I clinical trial.
Acta Oncol
; 55(2): 140-8, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26161618
3.
Aberrant intracellular IGF-1R beta-subunit makes receptor knockout cells (IGF1R-/-) susceptible to oncogenic transformation.
Exp Cell Res
; 315(8): 1458-67, 2009 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19302825
4.
Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK+ T-cell lymphoma.
J Hematol Oncol
; 12(1): 80, 2019 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31340850
5.
Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.
Mol Pharmacol
; 73(3): 930-9, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18070930
6.
CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol--potential role(s) for estrogen signaling.
FEBS J
; 275(8): 1778-89, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18331353
7.
Differential roles of SS18-SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth.
Biochem Biophys Res Commun
; 368(3): 793-800, 2008 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18267106
8.
Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.
Invest Ophthalmol Vis Sci
; 49(6): 2337-42, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18515579
9.
Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.
Invest Ophthalmol Vis Sci
; 49(6): 2620-6, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18515591
10.
Correction: The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway.
Oncogene
; 42(5): 407-408, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36526852
11.
Correction: Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK+ T-cell lymphoma.
J Hematol Oncol
; 16(1): 61, 2023 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37312210
12.
Insulin-like growth factor-I is an important antiapoptotic factor for rat leydig cells during postnatal development.
Endocrinology
; 148(1): 128-39, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17023532
13.
The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
Clin Cancer Res
; 12(4): 1383-91, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16489097
14.
Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I.
Clin Cancer Res
; 12(15): 4506-14, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16899596
15.
Phase I clinical trial of AXL1717 for treatment of relapsed malignant astrocytomas: analysis of dose and response.
Oncotarget
; 8(46): 81501-81510, 2017 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29113409
16.
GH effect on enzyme activity of 11betaHSD in abdominal obesity is dependent on treatment duration.
Eur J Endocrinol
; 154(1): 69-74, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16381993
17.
Expression and growth dependency of the insulin-like growth factor I receptor in craniopharyngioma cells: a novel therapeutic approach.
Clin Cancer Res
; 11(13): 4674-80, 2005 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16000560
18.
Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth.
Cancer Res
; 64(1): 236-42, 2004 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14729630
19.
The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway.
Oncogene
; 23(47): 7854-62, 2004 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-15334055
20.
Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells.
Med Oncol
; 32(7): 188, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26021470