Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Microbiome and Anticancer Immunosurveillance.

Zitvogel, Laurence; Ayyoub, Maha; Routy, Bertrand; Kroemer, Guido.

Cell ; 165(2): 276-87, 2016 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-27058662

2.

Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8⁺ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy.

Weulersse, Marianne; Asrir, Assia; Pichler, Andrea C; Lemaitre, Lea; Braun, Matthias; Carrié, Nadège; Joubert, Marie-Véronique; Le Moine, Marie; Do Souto, Laura; Gaud, Guillaume; Das, Indrajit; Brauns, Elisa; Scarlata, Clara M; Morandi, Elena; Sundarrajan, Ashmitha; Cuisinier, Marine; Buisson, Laure; Maheo, Sabrina; Kassem, Sahar; Agesta, Arantxa; Pérès, Michaël; Verhoeyen, Els; Martinez, Alejandra; Mazieres, Julien; Dupré, Loïc; Gossye, Thomas; Pancaldi, Vera; Guillerey, Camille; Ayyoub, Maha; Dejean, Anne S; Saoudi, Abdelhadi; Goriely, Stanislas; Avet-Loiseau, Hervé; Bald, Tobias; Smyth, Mark J; Martinet, Ludovic.

Immunity ; 53(4): 824-839.e10, 2020 10 13.

Artigo em Inglês | MEDLINE | ID: mdl-33053331

3.

Differential expression of the immunosuppressive enzyme IL4I1 in human induced Aiolos+, but not natural Helios+, FOXP3+ Treg cells.

Scarlata, Clara-Maria; Celse, Clotilde; Pignon, Pascale; Ayyoub, Maha; Valmori, Danila.

Eur J Immunol ; 45(2): 474-9, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25446972

4.

Links between genetics and immunology: mutations and antigens.

Ayyoub, Maha.

Bull Acad Natl Med ; 200(1): 67-79, 2016 Jan.

Artigo em Inglês, Francês | MEDLINE | ID: mdl-29889414

5.

Human memory Helios- FOXP3+ regulatory T cells (Tregs) encompass induced Tregs that express Aiolos and respond to IL-1ß by downregulating their suppressor functions.

Raffin, Caroline; Pignon, Pascale; Celse, Clotilde; Debien, Emilie; Valmori, Danila; Ayyoub, Maha.

J Immunol ; 191(9): 4619-27, 2013 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-24068664

6.

MHC class II/ESO tetramer-based generation of in vitro primed anti-tumor T-helper lines for adoptive cell therapy of cancer.

Poli, Caroline; Raffin, Caroline; Dojcinovic, Danijel; Luescher, Immanuel; Ayyoub, Maha; Valmori, Danila.

Haematologica ; 98(2): 316-22, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-22875619

7.

Ex vivo IL-1 receptor type I expression in human CD4+ T cells identifies an early intermediate in the differentiation of Th17 from FOXP3+ naive regulatory T cells.

Raffin, Caroline; Raimbaud, Isabelle; Valmori, Danila; Ayyoub, Maha.

J Immunol ; 187(10): 5196-202, 2011 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-21998454

8.

Human RORÎ³t+ TH17 cells preferentially differentiate from naive FOXP3+Treg in the presence of lineage-specific polarizing factors.

Valmori, Danila; Raffin, Caroline; Raimbaud, Isabelle; Ayyoub, Maha.

Proc Natl Acad Sci U S A ; 107(45): 19402-7, 2010 Nov 09.

Artigo em Inglês | MEDLINE | ID: mdl-20962281

9.

Monitoring of NY-ESO-1 specific CD4+ T cells using molecularly defined MHC class II/His-tag-peptide tetramers.

Ayyoub, Maha; Dojcinovic, Danijel; Pignon, Pascale; Raimbaud, Isabelle; Schmidt, Julien; Luescher, Immanuel; Valmori, Danila.

Proc Natl Acad Sci U S A ; 107(16): 7437-42, 2010 Apr 20.

Artigo em Inglês | MEDLINE | ID: mdl-20368442

10.

Distant antimetastatic effect of enterotropic colon cancer-derived α4ß7⁺CD8⁺ T cells.

Feliu, Virginie; Gomez-Roca, Carlos; Michelas, Marie; Thébault, Noémie; Lauzéral-Vizcaino, Françoise; Salvioni, Anna; Scandella, Lise; Sarot, Emeline; Valle, Carine; Balança, Camille-Charlotte; Scarlata, Clara-Maria; Delord, Jean-Pierre; Ayyoub, Maha; Devaud, Christel.

Sci Immunol ; 8(84): eadg8841, 2023 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-37289857

11.

Immune changes in hilar tumor draining lymph nodes following node sparing neoadjuvant chemoradiotherapy of localized cN0 non-small cell lung cancer.

Khalifa, Jonathan; Thébault, Noémie; Scarlata, Clara-Maria; Norkowski, Emma; Massabeau, Carole; Brouchet, Laurent; Peries Bataille, Sophie; Casaroli, Christelle; Vaz, Liza; Valle, Carine; Sarot, Emeline; Saint-Laurent, Nathalie; Martin, Etienne; Pages, Pierre-Benoît; Millière, Alice; Mazières, Julien; Cohen-Jonathan Moyal, Elizabeth; Lauzéral-Vizcaïno, Françoise; Ayyoub, Maha.

Front Oncol ; 13: 1269166, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-38074683

12.

Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t.

Ayyoub, Maha; Deknuydt, Florence; Raimbaud, Isabelle; Dousset, Christelle; Leveque, Lucie; Bioley, Gilles; Valmori, Danila.

Proc Natl Acad Sci U S A ; 106(21): 8635-40, 2009 May 26.

Artigo em Inglês | MEDLINE | ID: mdl-19439651

13.

Circulating Exhausted PD-1⁺CD39⁺ Helper CD4 T Cells Are Tumor-Antigen-Specific and Predict Response to PD-1/PD-L1 Axis Blockade.

Martinez-Gomez, Carlos; Michelas, Marie; Scarlata, Clara-Maria; Salvioni, Anna; Gomez-Roca, Carlos; Sarradin, Victor; Lauzéral-Vizcaino, Françoise; Féliu, Virginie; Dupret-Bories, Agnès; Ferron, Gwénaël; Sarini, Jérôme; Devaud, Christel; Delord, Jean-Pierre; Balança, Camille-Charlotte; Martinez, Alejandra; Ayyoub, Maha.

Cancers (Basel) ; 14(15)2022 Jul 28.

Artigo em Inglês | MEDLINE | ID: mdl-35954341

14.

Comment on "differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors".

Ayyoub, Maha; Valmori, Danila.

J Immunol ; 193(7): 3181, 2014 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-25240015

15.

Radiotherapy in the Era of Immunotherapy With a Focus on Non-Small-Cell Lung Cancer: Time to Revisit Ancient Dogmas?

Khalifa, Jonathan; Mazieres, Julien; Gomez-Roca, Carlos; Ayyoub, Maha; Moyal, Elizabeth Cohen-Jonathan.

Front Oncol ; 11: 662236, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33968769

16.

Phased differentiation of Î³Î´ T and T CD8 tumor-infiltrating lymphocytes revealed by single-cell transcriptomics of human cancers.

Cerapio, Juan-Pablo; Perrier, Marion; Balança, Camille-Charlotte; Gravelle, Pauline; Pont, Fréderic; Devaud, Christel; Franchini, Don-Marc; Féliu, Virginie; Tosolini, Marie; Valle, Carine; Lopez, Fréderic; Quillet-Mary, Anne; Ysebaert, Loic; Martinez, Alejandra; Delord, Jean Pierre; Ayyoub, Maha; Laurent, Camille; Fournie, Jean-Jacques.

Oncoimmunology ; 10(1): 1939518, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34721945

17.

Combining Nivolumab and Ipilimumab with Infliximab or Certolizumab in Patients with Advanced Melanoma: First Results of a Phase Ib Clinical Trial.

Montfort, Anne; Filleron, Thomas; Virazels, Mathieu; Dufau, Carine; Milhès, Jean; Pagès, Cécile; Olivier, Pascale; Ayyoub, Maha; Mounier, Muriel; Lusque, Amélie; Brayer, Stéphanie; Delord, Jean-Pierre; Andrieu-Abadie, Nathalie; Levade, Thierry; Colacios, Céline; Ségui, Bruno; Meyer, Nicolas.

Clin Cancer Res ; 27(4): 1037-1047, 2021 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-33272982

18.

PD-1 blockade restores helper activity of tumor-infiltrating, exhausted PD-1hiCD39+ CD4 T cells.

Balança, Camille-Charlotte; Salvioni, Anna; Scarlata, Clara-Maria; Michelas, Marie; Martinez-Gomez, Carlos; Gomez-Roca, Carlos; Sarradin, Victor; Tosolini, Marie; Valle, Carine; Pont, Frédéric; Ferron, Gwénaël; Gladieff, Laurence; Vergez, Sébastien; Dupret-Bories, Agnès; Mery, Eliane; Rochaix, Philippe; Fournié, Jean-Jacques; Delord, Jean-Pierre; Devaud, Christel; Martinez, Alejandra; Ayyoub, Maha.

JCI Insight ; 6(2)2021 01 25.

Artigo em Inglês | MEDLINE | ID: mdl-33332284

19.

Comment on "helios+ and helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans".

Ayyoub, Maha; Raffin, Caroline; Valmori, Danila.

J Immunol ; 190(9): 4439-40, 2013 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-23606718

20.

HLA class I - associated immunodominance affects CTL responsiveness to an ESO recombinant protein tumor antigen vaccine.

Bioley, Gilles; Guillaume, Philippe; Luescher, Immanuel; Yeh, Alice; Dupont, Bo; Bhardwaj, Nina; Mears, Gregory; Old, Lloyd J; Valmori, Danila; Ayyoub, Maha.

Clin Cancer Res ; 15(1): 299-306, 2009 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-19118058

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