Detalhe da pesquisa
1.
An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis.
Cell
; 175(2): 530-543.e24, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30220458
2.
DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis.
Nat Chem Biol
; 13(1): 46-53, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27820798
3.
Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice.
J Biol Chem
; 291(15): 8070-89, 2016 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26663085
4.
A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity.
Nat Chem Biol
; 10(8): 656-63, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24997602
5.
Preclinical Development of PNT6555, a Boronic Acid-Based, Fibroblast Activation Protein-α (FAP)-Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors.
J Nucl Med
; 65(1): 100-108, 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38050111
6.
Direct NMR observation and pKa determination of the Asp102 side chain in a serine protease.
J Am Chem Soc
; 134(4): 2348-54, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22229736
7.
Design and synthesis of boronic acid inhibitors of endothelial lipase.
Bioorg Med Chem Lett
; 22(3): 1397-401, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22225633
8.
4-Substituted boro-proline dipeptides: synthesis, characterization, and dipeptidyl peptidase IV, 8, and 9 activities.
Bioorg Med Chem Lett
; 22(17): 5536-40, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22853995
9.
Dipeptidyl Peptidase Inhibition Enhances CD8 T Cell Recruitment and Activates Intrahepatic Inflammasome in a Murine Model of Hepatocellular Carcinoma.
Cancers (Basel)
; 13(21)2021 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34771657
10.
Fibroblast activation protein is dispensable for control of glucose homeostasis and body weight in mice.
Mol Metab
; 19: 65-74, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30477988
11.
Circulating fibroblast activation protein and dipeptidyl peptidase 4 in rheumatoid arthritis and systemic sclerosis.
Int J Rheum Dis
; 21(11): 1915-1923, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27990763
12.
Synthesis and characterization of constrained peptidomimetic dipeptidyl peptidase IV inhibitors: amino-lactam boroalanines.
J Med Chem
; 50(10): 2391-8, 2007 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-17458948
13.
Abrogation of fibroblast activation protein enzymatic activity attenuates tumor growth.
Mol Cancer Ther
; 4(3): 351-60, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15767544
14.
Neuropeptide Y is a physiological substrate of fibroblast activation protein: Enzyme kinetics in blood plasma and expression of Y2R and Y5R in human liver cirrhosis and hepatocellular carcinoma.
Peptides
; 75: 80-95, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26621486
15.
Human FGF-21 Is a Substrate of Fibroblast Activation Protein.
PLoS One
; 11(3): e0151269, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26962859
16.
GLP-1(32-36)amide Pentapeptide Increases Basal Energy Expenditure and Inhibits Weight Gain in Obese Mice.
Diabetes
; 64(7): 2409-19, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25858562
17.
Tautomerism, acid-base equilibria, and H-bonding of the six histidines in subtilisin BPN' by NMR.
Protein Sci
; 12(4): 794-810, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12649438
18.
A pan inhibitor of DASH family enzymes induces immunogenic modulation and sensitizes murine and human carcinoma cells to antigen-specific cytotoxic T lymphocyte killing: implications for combination therapy with cancer vaccines.
Vaccine
; 32(26): 3223-31, 2014 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24731809
19.
Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase.
J Med Chem
; 56(9): 3467-77, 2013 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23594271
20.
The high-fat high-fructose hamster as an animal model for niacin's biological activities in humans.
Metabolism
; 62(12): 1840-9, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24035454