Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Effector T_H17 Cells Give Rise to Long-Lived T_RM Cells that Are Essential for an Immediate Response against Bacterial Infection.

Amezcua Vesely, Maria Carolina; Pallis, Paris; Bielecki, Piotr; Low, Jun Siong; Zhao, Jun; Harman, Christian C D; Kroehling, Lina; Jackson, Ruaidhrí; Bailis, Will; Licona-Limón, Paula; Xu, Hao; Iijima, Norifumi; Pillai, Padmini S; Kaplan, Daniel H; Weaver, Casey T; Kluger, Yuval; Kowalczyk, Monika S; Iwasaki, Akiko; Pereira, Joao P; Esplugues, Enric; Gagliani, Nicola; Flavell, Richard A.

Cell ; 178(5): 1176-1188.e15, 2019 08 22.

Artigo em Inglês | MEDLINE | ID: mdl-31442406

2.

Circuit Design Features of a Stable Two-Cell System.

Zhou, Xu; Franklin, Ruth A; Adler, Miri; Jacox, Jeremy B; Bailis, Will; Shyer, Justin A; Flavell, Richard A; Mayo, Avi; Alon, Uri; Medzhitov, Ruslan.

Cell ; 172(4): 744-757.e17, 2018 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-29398113

3.

Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis.

Nowarski, Roni; Jackson, Ruaidhrí; Gagliani, Nicola; de Zoete, Marcel R; Palm, Noah W; Bailis, Will; Low, Jun Siong; Harman, Christian C D; Graham, Morven; Elinav, Eran; Flavell, Richard A.

Cell ; 163(6): 1444-56, 2015 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-26638073

4.

ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency.

Cao, Zhendong; Budinich, Krista A; Huang, Hua; Ren, Diqiu; Lu, Bin; Zhang, Zhen; Chen, Qingzhou; Zhou, Yeqiao; Huang, Yu-Han; Alikarami, Fatemeh; Kingsley, Molly C; Lenard, Alexandra K; Wakabayashi, Aoi; Khandros, Eugene; Bailis, Will; Qi, Jun; Carroll, Martin P; Blobel, Gerd A; Faryabi, Robert B; Bernt, Kathrin M; Berger, Shelley L; Shi, Junwei.

Mol Cell ; 81(17): 3604-3622.e10, 2021 09 02.

Artigo em Inglês | MEDLINE | ID: mdl-34358447

5.

ß-Hydroxybutyrate suppresses colorectal cancer.

Dmitrieva-Posocco, Oxana; Wong, Andrea C; Lundgren, Patrick; Golos, Aleksandra M; Descamps, Hélène C; Dohnalová, Lenka; Cramer, Zvi; Tian, Yuhua; Yueh, Brian; Eskiocak, Onur; Egervari, Gabor; Lan, Yemin; Liu, Jinping; Fan, Jiaxin; Kim, Jihee; Madhu, Bhoomi; Schneider, Kai Markus; Khoziainova, Svetlana; Andreeva, Natalia; Wang, Qiaohong; Li, Ning; Furth, Emma E; Bailis, Will; Kelsen, Judith R; Hamilton, Kathryn E; Kaestner, Klaus H; Berger, Shelley L; Epstein, Jonathan A; Jain, Rajan; Li, Mingyao; Beyaz, Semir; Lengner, Christopher J; Katona, Bryson W; Grivennikov, Sergei I; Thaiss, Christoph A; Levy, Maayan.

Nature ; 605(7908): 160-165, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-35477756

6.

Skin-resident innate lymphoid cells converge on a pathogenic effector state.

Bielecki, Piotr; Riesenfeld, Samantha J; Hütter, Jan-Christian; Torlai Triglia, Elena; Kowalczyk, Monika S; Ricardo-Gonzalez, Roberto R; Lian, Mi; Amezcua Vesely, Maria C; Kroehling, Lina; Xu, Hao; Slyper, Michal; Muus, Christoph; Ludwig, Leif S; Christian, Elena; Tao, Liming; Kedaigle, Amanda J; Steach, Holly R; York, Autumn G; Skadow, Mathias H; Yaghoubi, Parastou; Dionne, Danielle; Jarret, Abigail; McGee, Heather M; Porter, Caroline B M; Licona-Limón, Paula; Bailis, Will; Jackson, Ruaidhrí; Gagliani, Nicola; Gasteiger, Georg; Locksley, Richard M; Regev, Aviv; Flavell, Richard A.

Nature ; 592(7852): 128-132, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33536623

7.

Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.

Bailis, Will; Shyer, Justin A; Zhao, Jun; Canaveras, Juan Carlos Garcia; Al Khazal, Fatimah J; Qu, Rihao; Steach, Holly R; Bielecki, Piotr; Khan, Omair; Jackson, Ruaidhri; Kluger, Yuval; Maher, Louis J; Rabinowitz, Joshua; Craft, Joe; Flavell, Richard A.

Nature ; 571(7765): 403-407, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31217581

8.

Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.

Bailis, Will; Shyer, Justin A; Zhao, Jun; Canaveras, Juan Carlos Garcia; Al Khazal, Fatimah J; Qu, Rihao; Steach, Holly R; Bielecki, Piotr; Khan, Omair; Jackson, Ruaidhri; Kluger, Yuval; Maher, Louis J; Rabinowitz, Joshua; Craft, Joe; Flavell, Richard A.

Nature ; 573(7773): E2, 2019 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-31447485

9.

The translation of non-canonical open reading frames controls mucosal immunity.

Jackson, Ruaidhrí; Kroehling, Lina; Khitun, Alexandra; Bailis, Will; Jarret, Abigail; York, Autumn G; Khan, Omair M; Brewer, J Richard; Skadow, Mathias H; Duizer, Coco; Harman, Christian C D; Chang, Lelina; Bielecki, Piotr; Solis, Angel G; Steach, Holly R; Slavoff, Sarah; Flavell, Richard A.

Nature ; 564(7736): 434-438, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30542152

10.

An in vivo screen of noncoding loci reveals that Daedalus is a gatekeeper of an Ikaros-dependent checkpoint during haematopoiesis.

Harman, Christian C D; Bailis, Will; Zhao, Jun; Hill, Louisa; Qu, Rihao; Jackson, Ruaidhrí P; Shyer, Justin A; Steach, Holly R; Kluger, Yuval; Goff, Loyal A; Rinn, John L; Williams, Adam; Henao-Mejia, Jorge; Flavell, Richard A.

Proc Natl Acad Sci U S A ; 118(3)2021 01 19.

Artigo em Inglês | MEDLINE | ID: mdl-33446502

11.

m⁶A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.

Li, Hua-Bing; Tong, Jiyu; Zhu, Shu; Batista, Pedro J; Duffy, Erin E; Zhao, Jun; Bailis, Will; Cao, Guangchao; Kroehling, Lina; Chen, Yuanyuan; Wang, Geng; Broughton, James P; Chen, Y Grace; Kluger, Yuval; Simon, Matthew D; Chang, Howard Y; Yin, Zhinan; Flavell, Richard A.

Nature ; 548(7667): 338-342, 2017 08 17.

Artigo em Inglês | MEDLINE | ID: mdl-28792938

12.

Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals.

Bailis, Will; Yashiro-Ohtani, Yumi; Fang, Terry C; Hatton, Robin D; Weaver, Casey T; Artis, David; Pear, Warren S.

Immunity ; 39(1): 148-59, 2013 Jul 25.

Artigo em Inglês | MEDLINE | ID: mdl-23890069

13.

T cell factor 1 is required for group 2 innate lymphoid cell generation.

Yang, Qi; Monticelli, Laurel A; Saenz, Steven A; Chi, Anthony Wei-Shine; Sonnenberg, Gregory F; Tang, Jiangbo; De Obaldia, Maria Elena; Bailis, Will; Bryson, Jerrod L; Toscano, Kristin; Huang, Jian; Haczku, Angela; Pear, Warren S; Artis, David; Bhandoola, Avinash.

Immunity ; 38(4): 694-704, 2013 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-23601684

14.

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan.

Kotzin, Jonathan J; Spencer, Sean P; McCright, Sam J; Kumar, Dinesh B Uthaya; Collet, Magalie A; Mowel, Walter K; Elliott, Ellen N; Uyar, Asli; Makiya, Michelle A; Dunagin, Margaret C; Harman, Christian C D; Virtue, Anthony T; Zhu, Stella; Bailis, Will; Stein, Judith; Hughes, Cynthia; Raj, Arjun; Wherry, E John; Goff, Loyal A; Klion, Amy D; Rinn, John L; Williams, Adam; Flavell, Richard A; Henao-Mejia, Jorge.

Nature ; 537(7619): 239-243, 2016 09 08.

Artigo em Inglês | MEDLINE | ID: mdl-27525555

15.

Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.

Yashiro-Ohtani, Yumi; Wang, Hongfang; Zang, Chongzhi; Arnett, Kelly L; Bailis, Will; Ho, Yugong; Knoechel, Birgit; Lanauze, Claudia; Louis, Lumena; Forsyth, Katherine S; Chen, Sujun; Chung, Yoonjie; Schug, Jonathan; Blobel, Gerd A; Liebhaber, Stephen A; Bernstein, Bradley E; Blacklow, Stephen C; Liu, Xiaole Shirley; Aster, Jon C; Pear, Warren S.

Proc Natl Acad Sci U S A ; 111(46): E4946-53, 2014 Nov 18.

Artigo em Inglês | MEDLINE | ID: mdl-25369933

16.

Notch and PI3K: how is the road traveled?

Bailis, Will; Pear, Warren S.

Blood ; 120(7): 1349-50, 2012 Aug 16.

Artigo em Inglês | MEDLINE | ID: mdl-22899471

17.

Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics.

Turner, Lucien; Van Le, Tran Ngoc; Cross, Eric; Queriault, Clemence; Knight, Montana; Trihemasava, Krittin; Davis, James; Schaefer, Patrick; Nguyen, Janet; Xu, Jimmy; Goldspiel, Brian; Hall, Elise; Rome, Kelly; Scaglione, Michael; Eggert, Joel; Au-Yeung, Byron; Wallace, Douglas C; Mesaros, Clementina; Baur, Joseph A; Bailis, Will.

Sci Immunol ; 9(93): eadj7238, 2024 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-38489349

18.

Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding.

Keeshan, Karen; Bailis, Will; Dedhia, Priya H; Vega, Maria E; Shestova, Olga; Xu, Lanwei; Toscano, Kristin; Uljon, Sacha N; Blacklow, Stephen C; Pear, Warren S.

Blood ; 116(23): 4948-57, 2010 Dec 02.

Artigo em Inglês | MEDLINE | ID: mdl-20805362

19.

Induction of APOBEC3 in vivo causes increased restriction of retrovirus infection.

Okeoma, Chioma M; Low, Audrey; Bailis, Will; Fan, Hung Y; Peterlin, B Matija; Ross, Susan R.

J Virol ; 83(8): 3486-95, 2009 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-19153238

20.

CRISPR/Cas9 Gene Targeting in Primary Mouse Bone Marrow-Derived Macrophages.

Bailis, Will.

Methods Mol Biol ; 2097: 223-230, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-31776929

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