Detalhe da pesquisa
1.
Synthesis and Evaluation of Prodrugs of α-Carboxy Nucleoside Phosphonates.
J Org Chem
; 87(21): 14793-14808, 2022 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36283025
2.
Enantiocontrolled Preparation of Ï-Substituted Cyclohexenones: Synthesis and Kinase Activity Assays of Cyclopropyl-Fused Cyclohexane Nucleosides.
Int J Mol Sci
; 23(17)2022 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36077100
3.
Dolutegravir Monotherapy of Simian Immunodeficiency Virus-Infected Macaques Selects for Several Patterns of Resistance Mutations with Variable Virological Outcomes.
J Virol
; 93(2)2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30381490
4.
Design, synthesis and evaluation of benzothiazole derivatives as multifunctional agents.
Bioorg Chem
; 101: 103960, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559579
5.
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
Bioorg Chem
; 97: 103665, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32086053
6.
Skin Damages-Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System.
Molecules
; 25(18)2020 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967192
7.
Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold.
Molecules
; 25(7)2020 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32272719
8.
Prodrugs of γ-Alkyl-Modified Nucleoside Triphosphates: Improved Inhibition of HIV Reverse Transcriptase.
Angew Chem Int Ed Engl
; 59(49): 22063-22071, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32379948
9.
Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models.
PLoS Pathog
; 12(9): e1005851, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27662652
10.
Synthesis of Guanine α-Carboxy Nucleoside Phosphonate (G-α-CNP), a Direct Inhibitor of Multiple Viral DNA Polymerases.
J Org Chem
; 83(17): 10510-10517, 2018 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30084243
11.
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
J Enzyme Inhib Med Chem
; 33(1): 1225-1238, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30141353
12.
Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics.
Proc Natl Acad Sci U S A
; 112(11): 3475-80, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25733891
13.
Synthesis and Antiviral Activity of Water-Soluble Polycarboxylic Derivatives of [60]Fullerene Loaded with 3,4-Dichlorophenyl Units.
Chem Biodivers
; 15(11): e1800293, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30168652
14.
6-Benzylidene-2-[4-(pyridin-3-ylcarboxy)benzylidene]cyclohexanones: A novel cluster of tumour-selective cytotoxins.
Bioorg Med Chem Lett
; 27(7): 1611-1615, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28238612
15.
A new four-component reaction involving the Michael addition and the Gewald reaction, leading to diverse biologically active 2-aminothiophenes.
Org Biomol Chem
; 15(18): 3892-3900, 2017 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28443928
16.
Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products.
Org Biomol Chem
; 15(5): 1130-1139, 2017 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28054092
17.
Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products.
Org Biomol Chem
; 15(5): 1268, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28101554
18.
New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity.
Bioorg Med Chem
; 25(17): 4637-4648, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28757102
19.
Screening Platform toward New Anti-HIV Aptamers Set on Molecular Docking and Fluorescence Quenching Techniques.
Anal Chem
; 88(4): 2327-34, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26810800
20.
ProTides of BVdU as potential anticancer agents upon efficient intracellular delivery of their activated metabolites.
Bioorg Med Chem Lett
; 26(23): 5618-5623, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27818111