Detalhe da pesquisa
1.
Analysis of the immunostimulatory effects of cytokine-expressing internal ribosome entry site-based RNA adjuvants and their applications.
J Infect Dis
; 2023 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37711050
2.
mRNA-HPV vaccine encoding E6 and E7 improves therapeutic potential for HPV-mediated cancers via subcutaneous immunization.
J Med Virol
; 95(12): e29309, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38100632
3.
Discovery of new 6-ureido/amidocoumarins as highly potent and selective inhibitors for the tumour-relevant carbonic anhydrases IX and XII.
J Enzyme Inhib Med Chem
; 38(1): 2154603, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36728712
4.
Discovery of 3-((3-amino-1H-indazol-4-yl)ethynyl)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide (AKE-72), a potent Pan-BCR-ABL inhibitor including the T315I gatekeeper resistant mutant.
J Enzyme Inhib Med Chem
; 38(1): 2228515, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37470410
5.
Overcoming the imatinib-resistant BCR-ABL mutants with new ureidobenzothiazole chemotypes endowed with potent and broad-spectrum anticancer activity.
J Enzyme Inhib Med Chem
; 38(1): 2189097, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927348
6.
Discovery of New Quinolone-Based Diarylamides as Potent B-RAFV600E/C-RAF Kinase Inhibitors Endowed with Promising In Vitro Anticancer Activity.
Int J Mol Sci
; 24(4)2023 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36834628
7.
Design and Synthesis of New 4-(3,4,5-Trimethoxyphenyl)Thiazole-Pyrimidine Derivatives as Potential Antiproliferative Agents.
Medicina (Kaunas)
; 59(6)2023 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37374282
8.
Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90.
Int J Mol Sci
; 21(24)2020 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33317068
9.
Nanoformulated Single-Stranded RNA-Based Adjuvant with a Coordinative Amphiphile as an Effective Stabilizer: Inducing Humoral Immune Response by Activation of Antigen-Presenting Cells.
Angew Chem Int Ed Engl
; 59(28): 11540-11549, 2020 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32239636
10.
Coordinative Amphiphiles as Tunable siRNA Transporters.
Bioconjug Chem
; 27(8): 1850-6, 2016 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27364494
11.
Ring Tension Applied to Thiol-Mediated Cellular Uptake.
Angew Chem Int Ed Engl
; 54(25): 7328-31, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25925500
12.
Cellular uptake of substrate-initiated cell-penetrating poly(disulfide)s.
J Am Chem Soc
; 136(16): 6069-74, 2014 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24735462
13.
Identification of Ureidocoumarin-Based Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors via Drug Repurposing Approach, Biological Evaluation, and In Silico Studies.
Pharmaceuticals (Basel)
; 17(4)2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38675389
14.
A lipid nanoparticle platform incorporating trehalose glycolipid for exceptional mRNA vaccine safety.
Bioact Mater
; 38: 486-498, 2024 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-38779592
15.
Substrate-initiated synthesis of cell-penetrating poly(disulfide)s.
J Am Chem Soc
; 135(6): 2088-2091, 2013 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23363440
16.
Dynamic amphiphile libraries to screen for the "fragrant" delivery of siRNA into HeLa cells and human primary fibroblasts.
J Am Chem Soc
; 135(25): 9295-8, 2013 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23767803
17.
Porous silicon surface modification via a microwave-induced in situ cyclic disulfide (S-S) cleavage and Si-S bond formation.
Colloids Surf B Biointerfaces
; 222: 113055, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36463610
18.
Identification of New N-methyl-piperazine Chalcones as Dual MAO-B/AChE Inhibitors.
Pharmaceuticals (Basel)
; 16(1)2023 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36678580
19.
Analyzing immune responses to varied mRNA and protein vaccine sequences.
NPJ Vaccines
; 8(1): 84, 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37271785
20.
Synthesis of an enlarged library of dynamic DNA activators with oxime, disulfide and hydrazone bridges.
Chemistry
; 18(33): 10436-43, 2012 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22589231