Middle East Respiratory Syndrome Coronavirus Infection Dynamics and Antibody Responses among Clinically Diverse Patients, Saudi Arabia.

Middle East respiratory syndrome coronavirus (MERS-CoV) shedding and antibody responses are not fully understood, particularly in relation to underlying medical conditions, clinical manifestations, and mortality. We enrolled MERS-CoV-positive patients at a hospital in Saudi Arabia and periodically collected specimens from multiple sites for real-time reverse transcription PCR and serologic testing. We conducted interviews and chart abstractions to collect clinical, epidemiologic, and laboratory information. We found that diabetes mellitus among survivors was associated with prolonged MERS-CoV RNA detection in the respiratory tract. Among case-patients who died, development of robust neutralizing serum antibody responses during the second and third week of illness was not sufficient for patient recovery or virus clearance. Fever and cough among mildly ill patients typically aligned with RNA detection in the upper respiratory tract; RNA levels peaked during the first week of illness. These findings should be considered in the development of infection control policies, vaccines, and antibody therapeutics.

Monkeypox stigma and risk communication; Understanding the dilemma.

Monkeypox (MPX) is a viral zoonotic disease that is endemic in Central and West African countries had affected countries in Asia, Europe, Africa, Australia, and South and North America. Some globally reported cases were linked to history of recent travel to endemic regions, however, official reports revealed homosexual practices among the majority of reported cases. In response to global increase MPX burden and number of cases, the WHO declared MPX a Public Health Emergency with International Concern (PHEIC) on July 23, 2022. The first MPX case in Saudi Arabia was a returning traveler from Europe to Riyadh on July 14, 2022. It is essential for policy makers to maintain neutral tone for health education messages and inform the public that MPX transmits via physical contact.

COVID-19 pandemic containment and management in city of Turaif: Understanding the experience.

Saudi Arabia implemented precautionary measures earlier before the first COVID-19 case had been confirmed. In March 02, 2020, the first COVID-19 was confirmed in Saudi Arabia which resulted in tightening precautionary measures. Turaif's location and population structure present a challenge for pandemic management. Multidisciplinary approach is essential to ensure efficiency of coordinated effortsbetween local authority and health officials.

Assessment of knowledge, attitude, and practice regarding Deep Margin Elevation (DME) among dental practitioners in Riyadh, Saudi Arabia.

OBJECTIVES: To evaluate Knowledge, Attitude, and Practice (KAP) regarding deep margin elevation (DME) among dental practitioners in Riyadh city. MATERIALS AND METHODOLOGY: A cross-sectional study that comprised a total number of 535 dental practitioners: 255 (47.7%) were males and 280 (52.3%) females. A self-constructed 21 close-ended self-administered questionnaire was utilized in the study. The data were entered and analyzed by Chi-square test and descriptive analysis using Statistical Package for the Social Sciences (SPSS) software. RESULTS: Although the majority of the respondents have heard about DME, only 30.4% have utilized this technique in their clinical practice by having general practitioners and specialists utilize this technique more often than consultants. Among the participants, 65.4% of them have agreed that adhesion by bonding to deep cervical dentin is predictable and related to the success of the final restoration. CONCLUSION: The knowledge level of DME among the study participants was adequate. The findings of this study revealed that the total number of dentists who utilize the technique in restoring large subgingival defects of posterior teeth with proximal caries is very minimal. Thus, it is recommended that dental practitioners have this technique introduced in their dental clinics as an alternative to surgical crown lengthening. Although years of experience and dentist rank may influence the clinical decision, in-depth factorial analysis with a greater sample size is necessary.

Wound Care Knowledge and Perception of the Saudi General Population in Riyadh Region.

Objective: Proper wound care and management are essential in health care facilities to prevent complications. There are many statistical studies on wound management both globally and in the Middle East. However, patient perception and knowledge regarding wound care have not been assessed in depth. Therefore, this study explored patient perception, attitude, and knowledge of wound care as well as the factors influencing patient perception among the Saudi population. Approach: This cross-sectional study included 414 individuals (mean age, 34 years; females, 64%) from varied social backgrounds who met the inclusion criteria. It was conducted in Riyadh, Kingdom of Saudi Arabia (KSA), from June to December 2019. Data were obtained from the participants using a pretested, validated self-administered questionnaire. Results: Of the participants, 78.0% completed a bachelor's degree or higher. The majority (71.7%) had an average level of knowledge regarding wound care. Most of the participants sought medical information from nonmedical resources-from social media (42.8%) and from relatives and friends (40.6%). Moreover, most of them (73.3%) used home remedies, 77.1% Vaseline, 71% butter, 70.2% coffee beans, 71.5% toothpaste, and 83.1% Zamzam water for their wounds. Innovation: This study is the first study to address the beliefs of the Saudi nonhealth care community toward wound care. Conclusion: Our findings revealed a gap between the level of education and knowledge and beliefs of our population, which could negatively affect clinical outcomes. To address this issue, there is a need to develop an awareness program on wound care and management for patients and providers.