The first species of Nemestrinidae (Diptera) endemic to Madagascar: A remarkable new species of Atriadops Wandolleck, 1897.

A new species of Nemestrinidae, Atriadops irwini Barraclough sp. nov., is described and illustrated from Sakaramy in the far north of Madagascar at about the same latitude as the Comoros Islands. The species was collected in lowland tropical forest by Dr Michael Irwin. Atriadops Wandolleck, 1897, is a small genus of Nemestrinidae in the subfamily Trichopisideinae. Six named species are distributed across the Australasian, Oriental, Afrotropical and Neotropical Regions. Atriadops irwini sp. nov. is thus only the seventh species in the genus (the first new species described in almost 70 years) and the second valid species from the Afrotropical Region. This is the first record of Atriadops from Madagascar, where the new species is the only endemic nemestrinid. Nycterimyia capensis Bezzi is the only other nemestrinid recorded from Madagascar, but it also occurs in South Africa (where it was first described) and Kenya. The world fauna of Atriadops is discussed and all known larval host records are listed.

Catalogue of the Diptera (Insecta) of Morocco- an annotated checklist, with distributions and a bibliography.

The faunistic knowledge of the Diptera of Morocco recorded from 1787 to 2021 is summarized and updated in this first catalogue of Moroccan Diptera species. A total of 3057 species, classified into 948 genera and 93 families (21 Nematocera and 72 Brachycera), are listed. Taxa (superfamily, family, genus and species) have been updated according to current interpretations, based on reviews in the literature, the expertise of authors and contributors, and recently conducted fieldwork. Data to compile this catalogue were primarily gathered from the literature. In total, 1225 references were consulted and some information was also obtained from online databases. Each family was reviewed and the checklist updated by the respective taxon expert(s), including the number of species that can be expected for that family in Morocco. For each valid species, synonyms known to have been used for published records from Morocco are listed under the currently accepted name. Where available, distribution within Morocco is also included. One new combination is proposed: Assuaniamelanoleuca (Séguy, 1941), comb. nov. (Chloropidae).

A striking new species of Prosoeca Schiner, 1867 (Diptera: Nemestrinidae): An important pollinator from the Bokkeveld Plateau, Northern Cape Province, South Africa.

For more than 20 years an undescribed species of Prosoeca has been referred to in numerous publications by pollination biologists, evolutionary biologists and ecologists, originally as being part of the Prosoeca peringueyi Lichtwardt, 1920, pollination guild. Ongoing research in these and related fields has necessitated the formal description of this large-bodied, striking new species, with a proboscis 1.5-2.3 x body length (mean proboscis length ± SD 36.25 ± 3.90 mm). Prosoeca marinusi Barraclough sp. nov. is described from a long series from the Hantam National Botanical Garden, Nieuwoudtville, Bokkeveld Plateau, Northern Cape Province, South Africa. The species is a narrow-range endemic and is restricted to the Nieuwoudtville area. Observations on the biology of the species are also presented. Prosoeca marinusi Barraclough sp. nov. is the only or main pollinator of at least four plant species (all regional endemics) in the family Iridaceae that flower from August to September. During August, Lapeirousia oreogena Goldblatt and Babiana vanzyliae L. Bolus are the main host flowers, while later in the spring season, Babiana framesii L. Bolus is most abundant in the Nieuwoudtville area.

A-kinase-interacting protein localizes protein kinase A in the nucleus.

The genetic variability and covalent modifications associated with the amino terminus of the protein kinase A (PKA) catalytic (C) subunit suggest that it may contribute to protein-protein interactions and/or localization. By using a yeast two-hybrid screen, we identified a PKA-interacting protein (AKIP1) that binds to the amino terminus (residues 1-39) of the C subunit of PKA. The interaction was localized to the A helix (residues 14-39) of the C subunit and to the carboxyl terminus of AKIP1. AKIP1 thus defines the amino-terminal A helix of PKA as a protein interaction motif. In normal breast (Hs 578 Bst) and HeLa cells, AKIP1 is present in the nucleus as speckles. A nuclear localization signal (Arg-14 and Arg-15) was identified. Upon stimulation with forskolin, HeLa cells expressing AKIP1 accumulated higher levels of the endogenous C subunit in the nucleus. Deletion of the carboxyl terminus of AKIP1 or overexpression of residues 1-39 of the C subunit abolished nuclear localization of the activated endogenous C subunit. Thus, AKIP1 describes a PKA-interacting protein that can contribute to localization by a mechanism that is distinct from A-kinase anchoring proteins that interact with the regulatory subunits.