Detalhe da pesquisa
1.
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy.
Proc Natl Acad Sci U S A
; 119(15): e2116887119, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377796
2.
Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage.
Am J Physiol Cell Physiol
; 326(3): C893-C904, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38284124
3.
KCNQ-Encoded Potassium Channels as Therapeutic Targets.
Annu Rev Pharmacol Toxicol
; 58: 625-648, 2018 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28992433
4.
SMIT (Sodium-Myo-Inositol Transporter) 1 Regulates Arterial Contractility Through the Modulation of Vascular Kv7 Channels.
Arterioscler Thromb Vasc Biol
; 40(10): 2468-2480, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787517
5.
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction.
Pflugers Arch
; 472(7): 881-898, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32506321
6.
Investigating the Role of G Protein ßγ in Kv7-Dependent Relaxations of the Rat Vasculature.
Arterioscler Thromb Vasc Biol
; 38(9): 2091-2102, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30002060
7.
G-protein ßγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity.
Proc Natl Acad Sci U S A
; 112(20): 6497-502, 2015 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25941381
8.
Synergistic interplay of Gßγ and phosphatidylinositol 4,5-bisphosphate dictates Kv7.4 channel activity.
Pflugers Arch
; 469(2): 213-223, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27981364
9.
Kv7 Channel Activation Underpins EPAC-Dependent Relaxations of Rat Arteries.
Arterioscler Thromb Vasc Biol
; 36(12): 2404-2411, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27789473
10.
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of K(v)7.2 potassium channel subunits.
Proc Natl Acad Sci U S A
; 110(11): 4386-91, 2013 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23440208
11.
Large conductance calcium-activated potassium channels: their expression and modulation of glutamate release from nerve terminals isolated from rat trigeminal caudal nucleus and cerebral cortex.
Neurochem Res
; 39(5): 901-10, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24667981
12.
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons.
Pharmacol Res
; 87: 80-6, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24973659
13.
Key role for Kv11.1 (ether-a-go-go related gene) channels in rat bladder contractility.
Physiol Rep
; 11(3): e15583, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36750122
14.
Marked oestrous cycle-dependent regulation of rat arterial KV 7.4 channels driven by GPER1.
Br J Pharmacol
; 180(2): 174-193, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36085551
15.
Crucial role for Sodium Hydrogen Exchangers in SGLT2 inhibitor-induced arterial relaxations.
bioRxiv
; 2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38116028
16.
Kv7.4 channels regulate potassium permeability in neuronal mitochondria.
Biochem Pharmacol
; 197: 114931, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35085542
17.
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity.
J Med Chem
; 65(16): 11340-11364, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35972998
18.
Dynein regulates Kv7.4 channel trafficking from the cell membrane.
J Gen Physiol
; 153(3)2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33533890
19.
Pre-synaptic BK channels selectively control glutamate versus GABA release from cortical and hippocampal nerve terminals.
J Neurochem
; 115(2): 411-22, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20681950
20.
Expression, localization, and pharmacological role of Kv7 potassium channels in skeletal muscle proliferation, differentiation, and survival after myotoxic insults.
J Pharmacol Exp Ther
; 332(3): 811-20, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20040580