Association between vitamin D serum levels and clinical, laboratory, and parasitological parameters in patients with malaria from an endemic area of the Amazon.

BACKGROUND: Some studies have suggested the importance of vitamin D [25(OH)D] in malaria clinical practice. The prevalence of 25(OH)D deficiency in the Amazon population is not well known, and there are few studies in patients with malaria. This study aimed to evaluate 25(OH)D serum levels in patients with malaria and determine their relationships with epidemiological, clinical, laboratory, and parasitemia data. METHODS: An analytical cross-sectional study of 123 patients with malaria and 122 individuals without malaria was performed in Itaituba, Pará, Brazil, from January 2018 to October 2019, by evaluating sociodemographic, clinical-epidemiological, parasitological, and laboratory data and adopting a 5% significance level. Parametric tests (Student's t-test), non-parametric tests (Mann-Whitney U), and Spearman's correlation ([rs], for non-parametric variables) were used according to the nature of the distribution of the variables. For the qualitative variables, Pearson's chi-square test, Fisher's exact test, and the G test were used. Spearman's correlation was used to compare the results of the 25(OH)D levels and blood counts performed among patients and the control group. RESULTS: Malaria patients residing in a mining area had 25(OH)D serum levels that were significantly lower than those in the control group residing in the mining area, though both were within normal levels. Red blood cell counts had an inverse correlation with parasitemia (Plasmodium falciparum), and platelet levels had an inverse correlation with parasitemia (Plasmodium vivax). 25(OH)D deficiency was evidenced in Itaituba, in the state of Pará, which is an endemic area of malaria in the Amazon region.

Consumo Alimentar de Macronutrientes e Estado Nutricional de Pessoas com Estomia / Food Consumption of Macronutrients and Nutritional Status of People With Ostomy / Consumo Alimentario de Macronutrientes y Estado Nutricional de Personas con Ostomía

Objetivo:Avaliar o consumo alimentar de macronutrientes e o estado nutricional de pessoas com estomia no contexto amazônico. Método: Estudo transversal quantitativo realizado na unidade de referência especializada às pessoas com estomia, no período de janeiro a março de 2020. A amostra foi constituída de 77 pessoas com estomias, com idade de 21 a 88 anos, de ambos os sexos. Foram utilizados informações sociodemográficas, aspectos clínicos e comportamentais, medidas antropométricas e recordatório 24 h. A análise estatística foi realizada por meio dos softwares BioEstat 5.0 e EpiInfo 3.5.1. Resultados: A maioria era do sexo masculino, com faixa etária entre 35 e 50 anos. Os tipos mais frequentes de estomia foram: colostomia (69%) e ileostomia (21%), com caráter temporário (43%), tendo em ambos os sexos a etiologia neoplásica (60%). Quanto ao estado nutricional, a maioria apresentou eutrofia segundo o índice de massa corporal, no entanto a circunferência da cintura demonstrou risco metabólico aumentado no sexo feminino, e a prega cutânea tricipital indicou obesidade no sexo masculino e eutrofia no sexo feminino (<0,0001). Com relação ao consumo alimentar, observou-se inadequação de energia e de macronutrientes. Conclusão: Os hábitos alimentares no contexto amazônico podem estar relacionados ao consumo alimentar inadequado e às alterações no estado nutricional.

Objective:To evaluate the food intake of macronutrients and nutritional status of people with ostomy in the Amazonian context. Method: Quantitative cross-sectional study carried out in the specialized reference unit for people with ostomy, in the period from January to March 2020. The sample consisted of 77 people with ostomies, aged 21 to 88 years old, of both genders. We used sociodemographic information, clinical and behavioral aspects, anthropometric measurements and 24-hour recall. Statistical analysis was performed using BioEstat 5.0 and EpiInfo 3.5.1 software. Results: Most were male, aged between 35 and 50 years old. The most frequent types of ostomy were: colostomy (69%) and ileostomy (21%), with a temporary nature (43%), with neoplastic etiology in both sexes (60%). As for the nutritional status, most presented eutrophy according to the body mass index, but waist circumference showed increased metabolic risk in females, and the triceps skinfold thickness indicated excess adiposity in males (<0.0001). Regarding food consumption, there was inadequacy of energy and macronutrients. Conclusion: Eating habits in the Amazonian context may be related to inadequate food consumption and changes in nutritional status.

Objetivo:Evaluar el consumo alimentario de macronutrientes y el estado nutricional de personas con estoma en el contexto amazónico. Método: Estudio transversal cuantitativo, realizado en la Unidad de Referencia Especializada en personas con ostomía durante el periodo de enero a marzo del 2020. La muestra estuvo constituida por 77 personas con estoma. Entre los 21 y los 88 años, de los dos sexos. Se usó información sociodemográfica, aspectos clínicos, comportamentales, medidas antropométricas y recordatorio de 24 horas. El análisis estadístico se realizó con los programas BioEstat 5.0 y EpiInfo 3.5.1. Resultados: La mayoría eran de sexo masculino, con un grupo etario de 35 a 50 años. Los tipos de ostomía más frecuentes fueron: colostomía (69%) e ileostomía (21%), de carácter temporal (43%), con etiología neoplásica en ambos sexos (60%).Por otro lado, con relación al estado nutricional, la mayoría presentó eutrofia según el índice de masa corporal. Sin embargo, la circunferencia de cintura demostró riesgo metabólico más grande en el sexo femenino y el pliegue cutáneo tricipital indicó exceso de adiposidad en el sexo masculino y eutrofia en feminino (<0,0001). Con relación al consumo alimentario, se observó la inadecuación de energía y macronutrientes. Conclusión: Los hábitos alimentarios en el contexto amazónico pueden estar relacionados con el consumo inadecuado de alimentos y cambios en el estado nutricional.