Detalhe da pesquisa
1.
Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington's disease model.
Hum Mol Genet
; 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38776957
2.
Increased plasma melatonin in presymptomatic Huntington disease sheep (Ovis aries): Compensatory neuroprotection in a neurodegenerative disease?
J Pineal Res
; 68(2): e12624, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31742766
3.
Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.
Proc Natl Acad Sci U S A
; 114(52): E11293-E11302, 2017 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229845
4.
Early and progressive circadian abnormalities in Huntington's disease sheep are unmasked by social environment.
Hum Mol Genet
; 23(13): 3375-83, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24488771
5.
Somatic CAG Repeat Stability in a Transgenic Sheep Model of Huntington's Disease.
J Huntingtons Dis
; 13(1): 33-40, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38393920
6.
An ovine transgenic Huntington's disease model.
Hum Mol Genet
; 19(10): 1873-82, 2010 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20154343
7.
Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci.
Elife
; 102021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34227937
8.
Expression patterns of keratin intermediate filament and keratin associated protein genes in wool follicles.
Differentiation
; 77(3): 307-16, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19272529
9.
Correction: Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci.
Elife
; 122023 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37831065
10.
Metabolic profiling of presymptomatic Huntington's disease sheep reveals novel biomarkers.
Sci Rep
; 7: 43030, 2017 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28223686
11.
Alzheimer's disease markers in the aged sheep (Ovis aries).
Neurobiol Aging
; 58: 112-119, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28728117
12.
Metabolic disruption identified in the Huntington's disease transgenic sheep model.
Sci Rep
; 6: 20681, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26864449
13.
Rapid and Progressive Regional Brain Atrophy in CLN6 Batten Disease Affected Sheep Measured with Longitudinal Magnetic Resonance Imaging.
PLoS One
; 10(7): e0132331, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26161747
14.
Further molecular characterisation of the OVT73 transgenic sheep model of Huntington's disease identifies cortical aggregates.
J Huntingtons Dis
; 2(3): 279-95, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-25062676
15.
An updated nomenclature for keratin-associated proteins (KAPs).
Int J Biol Sci
; 8(2): 258-64, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22298953
16.
Complex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integration.
Nat Genet
; 44(4): 390-7, S1, 2012 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22388000