Detalhe da pesquisa
1.
Picornaviral polymerase domain exchanges reveal a modular basis for distinct biochemical activities of viral RNA-dependent RNA polymerases.
J Biol Chem
; 295(31): 10624-10637, 2020 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32493771
2.
Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase.
J Virol
; 91(12)2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28381577
3.
Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J Biol Chem
; 291(27): 13999-14011, 2016 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27137934
4.
Structure-function relationships underlying the replication fidelity of viral RNA-dependent RNA polymerases.
J Virol
; 89(1): 275-86, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25320316
5.
Coxsackievirus B3 mutator strains are attenuated in vivo.
Proc Natl Acad Sci U S A
; 109(34): E2294-303, 2012 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22853955
6.
Mixed Infections Unravel Novel HCV Inter-Genotypic Recombinant Forms within the Conserved IRES Region.
Viruses
; 16(4)2024 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38675902
7.
A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach.
Sci Rep
; 13(1): 12798, 2023 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37550340
8.
Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds.
PLoS Pathog
; 6(10): e1001163, 2010 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21060812
9.
Attenuation of RNA viruses by redirecting their evolution in sequence space.
Nat Microbiol
; 2: 17088, 2017 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28581455
10.
Autophagy is a prosurvival mechanism in cells expressing an autosomal dominant familial neurohypophyseal diabetes insipidus mutant vasopressin transgene.
FASEB J
; 19(8): 1021-3, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15781609
11.
Deciphering the mechanisms of homeostatic plasticity in the hypothalamo-neurohypophyseal system--genomic and gene transfer strategies.
Prog Biophys Mol Biol
; 84(2-3): 151-82, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-14769434
12.
Ribavirin: a drug active against many viruses with multiple effects on virus replication and propagation. Molecular basis of ribavirin resistance.
Curr Opin Virol
; 8: 10-5, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24846716
13.
Emergence and transmission of arbovirus evolutionary intermediates with epidemic potential.
Cell Host Microbe
; 15(6): 706-16, 2014 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24922573
14.
Isolation of fidelity variants of RNA viruses and characterization of virus mutation frequency.
J Vis Exp
; (52)2011 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21712796
15.
NO-cGMP mediated galanin expression in NGF-deprived or axotomized sensory neurons.
J Neurochem
; 100(3): 790-801, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17263797
16.
Distinct roles for protein kinase C isoforms in regulating platelet purinergic receptor function.
Mol Pharmacol
; 70(3): 1132-42, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16804093
17.
Molecular epidemiology of hepatitis C virus subtype 3a in injecting drug users.
J Med Virol
; 78(10): 1296-303, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16927280
18.
Clinical utility of total HCV core antigen quantification: a new indirect marker of HCV replication.
Hepatology
; 36(1): 211-8, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12085367