Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

The environmental impact of inhaled therapy: making informed treatment choices.

Woodcock, Ashley; Beeh, Kai M; Sagara, Hironori; Aumônier, Simon; Addo-Yobo, Emmanuel; Khan, Javaid; Vestbo, Jørgen; Tope, Helen.

Eur Respir J ; 60(1)2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-34916263

2.

Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme.

Krug, Norbert; Hohlfeld, Jens M; Kirsten, Anne-Marie; Kornmann, Oliver; Beeh, Kai M; Kappeler, Dominik; Korn, Stephanie; Ignatenko, Stanislav; Timmer, Wolfgang; Rogon, Cordelia; Zeitvogel, Jana; Zhang, Nan; Bille, Joachim; Homburg, Ursula; Turowska, Agnieszka; Bachert, Claus; Werfel, Thomas; Buhl, Roland; Renz, Jonas; Garn, Holger; Renz, Harald.

N Engl J Med ; 372(21): 1987-95, 2015 May 21.

Artigo em Inglês | MEDLINE | ID: mdl-25981191

3.

How Do Dual Long-Acting Bronchodilators Prevent Exacerbations of Chronic Obstructive Pulmonary Disease?

Beeh, Kai M; Burgel, Pierre-Regis; Franssen, Frits M E; Lopez-Campos, Jose Luis; Loukides, Stelios; Hurst, John R; Flezar, Matjaz; Ulrik, Charlotte Suppli; Di Marco, Fabiano; Stolz, Daiana; Valipour, Arschang; Casserly, Brian; Ställberg, Björn; Kostikas, Konstantinos; Wedzicha, Jadwiga A.

Am J Respir Crit Care Med ; 196(2): 139-149, 2017 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-27922741

4.

Assessing the clinical value of fast onset and sustained duration of action of long-acting bronchodilators for COPD.

Cazzola, Mario; Beeh, Kai M; Price, David; Roche, Nicolas.

Pulm Pharmacol Ther ; 31: 68-78, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25727846

5.

Minimal clinically important differences in pharmacological trials.

Jones, Paul W; Beeh, Kai M; Chapman, Kenneth R; Decramer, Marc; Mahler, Donald A; Wedzicha, Jadwiga A.

Am J Respir Crit Care Med ; 189(3): 250-5, 2014 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-24383418

6.

Tiotropium versus salmeterol for the prevention of exacerbations of COPD.

Vogelmeier, Claus; Hederer, Bettina; Glaab, Thomas; Schmidt, Hendrik; Rutten-van Mölken, Maureen P M H; Beeh, Kai M; Rabe, Klaus F; Fabbri, Leonardo M.

N Engl J Med ; 364(12): 1093-1103, 2011 Mar 24.

Artigo em Inglês | MEDLINE | ID: mdl-21428765

7.

Aclidinium improves exercise endurance, dyspnea, lung hyperinflation, and physical activity in patients with COPD: a randomized, placebo-controlled, crossover trial.

Beeh, Kai M; Watz, Henrik; Puente-Maestu, Luis; de Teresa, Luis; Jarreta, Diana; Caracta, Cynthia; Garcia Gil, Esther; Magnussen, Helgo.

BMC Pulm Med ; 14: 209, 2014 Dec 23.

Artigo em Inglês | MEDLINE | ID: mdl-25539654

8.

Characterisation of exacerbation risk and exacerbator phenotypes in the POET-COPD trial.

Beeh, Kai M; Glaab, Thomas; Stowasser, Susanne; Schmidt, Hendrik; Fabbri, Leonardo M; Rabe, Klaus F; Vogelmeier, Claus F.

Respir Res ; 14: 116, 2013 Oct 29.

Artigo em Inglês | MEDLINE | ID: mdl-24168767

9.

Cost-Effectiveness of Single- versus Multiple-Inhaler Triple Therapy in a UK COPD Population: The INTREPID Trial.

Halpin, David M G; Kendall, Robyn; Shukla, Soham; Martin, Alan; Shah, Dhvani; Midwinter, Dawn; Beeh, Kai M; Kocks, Janwillem W H; Jones, Paul W; Compton, Chris; Risebrough, Nancy A; Ismaila, Afisi S.

Int J Chron Obstruct Pulmon Dis ; 17: 2745-2755, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36317185

10.

Maximizing Adherence and Gaining New Information For Your Chronic Obstructive Pulmonary Disease (MAGNIFY COPD): Study Protocol for the Pragmatic, Cluster Randomized Trial Evaluating the Impact of Dual Bronchodilator with Add-On Sensor and Electronic Monitoring on Clinical Outcomes.

Price, David; Jones, Rupert; Pfister, Pascal; Cao, Hui; Carter, Victoria; Kemppinen, Anu; Holzhauer, Björn; Kaplan, Alan; Clark, Allan; Halpin, David M G; Pinnock, Hilary; Chalmers, James D; van Boven, Job F M; Beeh, Kai M; Kostikas, Konstantinos; Roche, Nicolas; Usmani, Omar; Mastoridis, Paul.

Pragmat Obs Res ; 12: 25-35, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34079422

11.

Indacaterol, a novel inhaled, once-daily, long-acting beta2-agonist for the treatment of obstructive airways diseases.

Beeh, Kai M; Beier, Jutta.

Adv Ther ; 26(7): 691-9, 2009 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-19609496

12.

Is there a role for antiinflammatory treatment in COPD?

Beeh, Kai M; Glaab, Thomas.

COPD ; 6(5): 395-403, 2009 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-19863369

13.

Dose-response of an extrafine dry powder inhaler formulation of glycopyrronium bromide: randomized, double-blind, placebo-controlled, dose-ranging study (GlycoNEXT).

Beeh, Kai M; Emirova, Aida; Prunier, Hélène; Santoro, Debora; Nandeuil, Marie Anna.

Int J Chron Obstruct Pulmon Dis ; 13: 1701-1711, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-29872288

14.

ACTIVATE: the effect of aclidinium/formoterol on hyperinflation, exercise capacity, and physical activity in patients with COPD.

Watz, Henrik; Troosters, Thierry; Beeh, Kai M; Garcia-Aymerich, Judith; Paggiaro, Pierluigi; Molins, Eduard; Notari, Massimo; Zapata, Antonio; Jarreta, Diana; Garcia Gil, Esther.

Int J Chron Obstruct Pulmon Dis ; 12: 2545-2558, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28883722

15.

The Role of Bronchodilators in Preventing Exacerbations of Chronic Obstructive Pulmonary Disease.

Beeh, Kai M.

Tuberc Respir Dis (Seoul) ; 79(4): 241-247, 2016 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-27790275

16.

Early bronchodilator action of glycopyrronium versus tiotropium in moderate-to-severe COPD patients: a cross-over blinded randomized study (Symptoms and Pulmonary function in the moRnING).

Marin, Jose M; Beeh, Kai M; Clemens, Andreas; Castellani, Walter; Schaper, Lennart; Saralaya, Dinesh; Gunstone, Anthony; Casamor, Ricard; Kostikas, Konstantinos; Aalamian-Mattheis, Maryam.

Int J Chron Obstruct Pulmon Dis ; 11: 1425-34, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-27418815

17.

Tiotropium and Salmeterol in COPD Patients at Risk of Exacerbations: A Post Hoc Analysis from POET-COPD(®).

Vogelmeier, Claus F; Asijee, Guus M; Kupas, Katrin; Beeh, Kai M.

Adv Ther ; 32(6): 537-47, 2015 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-26100349

18.

Long-term repeatability of induced sputum cells and inflammatory markers in stable, moderately severe COPD.

Beeh, Kai M; Beier, Jutta; Kornmann, Oliver; Mander, Annette; Buhl, Roland.

Chest ; 123(3): 778-83, 2003 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-12628878

19.

Neutrophil chemotactic activity of sputum from patients with COPD: role of interleukin 8 and leukotriene B4.

Beeh, Kai M; Kornmann, Oliver; Buhl, Roland; Culpitt, Sarah V; Giembycz, Mark A; Barnes, Peter J.

Chest ; 123(4): 1240-7, 2003 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-12684317

20.

And Then There Were Three: Time to Move Onward in COPD Drug Development Beyond LAMA/LABA/ICS at Last?