Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Illuminating the path to DNA repair.

Gupta, Darshana; Beisel, Chase L.

Cell ; 184(22): 5503-5505, 2021 10 28.

Artigo em Inglês | MEDLINE | ID: mdl-34715020

2.

For the CRISPR Fan(zor)atics: RNA-guided DNA endonucleases discovered in eukaryotes.

Patinios, Constantinos; Beisel, Chase L.

Mol Cell ; 83(17): 3046-3048, 2023 09 07.

Artigo em Inglês | MEDLINE | ID: mdl-37683609

3.

Rapid cell-free characterization of multi-subunit CRISPR effectors and transposons.

Wimmer, Franziska; Mougiakos, Ioannis; Englert, Frank; Beisel, Chase L.

Mol Cell ; 82(6): 1210-1224.e6, 2022 03 17.

Artigo em Inglês | MEDLINE | ID: mdl-35216669

4.

Anti-CRISPR prediction using deep learning reveals an inhibitor of Cas13b nucleases.

Wandera, Katharina G; Alkhnbashi, Omer S; Bassett, Harris V I; Mitrofanov, Alexander; Hauns, Sven; Migur, Anzhela; Backofen, Rolf; Beisel, Chase L.

Mol Cell ; 82(14): 2714-2726.e4, 2022 07 21.

Artigo em Inglês | MEDLINE | ID: mdl-35649413

5.

The miniature CRISPR-Cas12m effector binds DNA to block transcription.

Wu, Wen Y; Mohanraju, Prarthana; Liao, Chunyu; Adiego-Pérez, Belén; Creutzburg, Sjoerd C A; Makarova, Kira S; Keessen, Karlijn; Lindeboom, Timon A; Khan, Tahseen S; Prinsen, Stijn; Joosten, Rob; Yan, Winston X; Migur, Anzhela; Laffeber, Charlie; Scott, David A; Lebbink, Joyce H G; Koonin, Eugene V; Beisel, Chase L; van der Oost, John.

Mol Cell ; 82(23): 4487-4502.e7, 2022 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-36427491

6.

The tracrRNA in CRISPR Biology and Technologies.

Liao, Chunyu; Beisel, Chase L.

Annu Rev Genet ; 55: 161-181, 2021 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-34416117

7.

RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.

Bravo, Jack P K; Hallmark, Thomson; Naegle, Bronson; Beisel, Chase L; Jackson, Ryan N; Taylor, David W.

Nature ; 613(7944): 582-587, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36599980

8.

Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA.

Dmytrenko, Oleg; Neumann, Gina C; Hallmark, Thomson; Keiser, Dylan J; Crowley, Valerie M; Vialetto, Elena; Mougiakos, Ioannis; Wandera, Katharina G; Domgaard, Hannah; Weber, Johannes; Gaudin, Thomas; Metcalf, Josie; Gray, Benjamin N; Begemann, Matthew B; Jackson, Ryan N; Beisel, Chase L.

Nature ; 613(7944): 588-594, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36599979

9.

Your Base Editor Might Be Flirting with Single (Stranded) DNA: Faithful On-Target CRISPR Base Editing without Promiscuous Deamination.

Collins, Scott P; Beisel, Chase L.

Mol Cell ; 79(5): 703-704, 2020 09 03.

Artigo em Inglês | MEDLINE | ID: mdl-32888434

10.

CRISPR-based screening of small RNA modulators of bile susceptibility in Bacteroides thetaiotaomicron.

Prezza, Gianluca; Liao, Chunyu; Reichardt, Sarah; Beisel, Chase L; Westermann, Alexander J.

Proc Natl Acad Sci U S A ; 121(6): e2311323121, 2024 Feb 06.

Artigo em Inglês | MEDLINE | ID: mdl-38294941

11.

CRISPR RNA-Dependent Binding and Cleavage of Endogenous RNAs by the Campylobacter jejuni Cas9.

Dugar, Gaurav; Leenay, Ryan T; Eisenbart, Sara K; Bischler, Thorsten; Aul, Belinda U; Beisel, Chase L; Sharma, Cynthia M.

Mol Cell ; 69(5): 893-905.e7, 2018 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-29499139

12.

Rapid and Scalable Characterization of CRISPR Technologies Using an E. coli Cell-Free Transcription-Translation System.

Marshall, Ryan; Maxwell, Colin S; Collins, Scott P; Jacobsen, Thomas; Luo, Michelle L; Begemann, Matthew B; Gray, Benjamin N; January, Emma; Singer, Anna; He, Yonghua; Beisel, Chase L; Noireaux, Vincent.

Mol Cell ; 69(1): 146-157.e3, 2018 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-29304331

13.

Expanding the flexibility of base editing for high-throughput genetic screens in bacteria.

Gawlitt, Sandra; Collins, Scott P; Yu, Yanying; Blackman, Samuel A; Barquist, Lars; Beisel, Chase L.

Nucleic Acids Res ; 52(7): 4079-4097, 2024 Apr 24.

Artigo em Inglês | MEDLINE | ID: mdl-38499498

14.

Interrogating two extensively self-targeting Type I CRISPR-Cas systems in Xanthomonas albilineans reveals distinct anti-CRISPR proteins that block DNA degradation.

Wimmer, Franziska; Englert, Frank; Wandera, Katharina G; Alkhnbashi, Omer S; Collins, Scott P; Backofen, Rolf; Beisel, Chase L.

Nucleic Acids Res ; 52(2): 769-783, 2024 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-38015466

15.

Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity.

Vialetto, Elena; Miele, Solange; Goren, Moran G; Yu, Jiaqi; Yu, Yanying; Collias, Daphne; Beamud, Beatriz; Osbelt, Lisa; Lourenço, Marta; Strowig, Till; Brisse, Sylvain; Barquist, Lars; Qimron, Udi; Bikard, David; Beisel, Chase L.

Nucleic Acids Res ; 2024 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-38661215

16.

An adapted method for Cas9-mediated editing reveals the species-specific role of ß-glucoside utilization driving competition between Klebsiella species.

Almási, Éva D H; Knischewski, Nele; Osbelt, Lisa; Muthukumarasamy, Uthayakumar; El Mouali, Youssef; Vialetto, Elena; Beisel, Chase L; Strowig, Till.

J Bacteriol ; 206(3): e0031723, 2024 Mar 21.

Artigo em Inglês | MEDLINE | ID: mdl-38353529

17.

Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems.

Leenay, Ryan T; Maksimchuk, Kenneth R; Slotkowski, Rebecca A; Agrawal, Roma N; Gomaa, Ahmed A; Briner, Alexandra E; Barrangou, Rodolphe; Beisel, Chase L.

Mol Cell ; 62(1): 137-47, 2016 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-27041224

18.

CRISPR memories in single cells.

Sparmann, Anke; Beisel, Chase L.

Mol Syst Biol ; 18(4): e11011, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35467081

19.

Shortened CRISPR-Cas9 arrays enable multiplexed gene targeting in bacteria from a smaller DNA footprint.

Gawlitt, Sandra; Liao, Chunyu; Achmedov, Tatjana; Beisel, Chase L.

RNA Biol ; 20(1): 666-680, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-37654098

20.

Sequence-independent RNA sensing and DNA targeting by a split domain CRISPR-Cas12a gRNA switch.

Collins, Scott P; Rostain, William; Liao, Chunyu; Beisel, Chase L.

Nucleic Acids Res ; 49(5): 2985-2999, 2021 03 18.

Artigo em Inglês | MEDLINE | ID: mdl-33619539

BVS Doenças Infecciosas e Parasitárias

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar: