Comparison of measured with calculated dose distribution from a 120-MeV electron beam from a laser-plasma accelerator.

PURPOSE: To evaluate the dose distribution of a 120-MeV laser-plasma accelerated electron beam which may be of potential interest for high-energy electron radiation therapy. METHODS: In the interaction between an intense laser pulse and a helium gas jet, a well collimated electron beam with very high energy is produced. A secondary laser beam is used to optically control and to tune the electron beam energy and charge. The potential use of this beam for radiation treatment is evaluated experimentally by measurements of dose deposition in a polystyrene phantom. The results are compared to Monte Carlo simulations using the geant4 code. RESULTS: It has been shown that the laser-plasma accelerated electron beam can deliver a peak dose of more than 1 Gy at the entrance of the phantom in a single laser shot by direct irradiation, without the use of intermediate magnetic transport or focusing. The dose distribution is peaked on axis, with narrow lateral penumbra. Monte Carlo simulations of electron beam propagation and dose deposition indicate that the propagation of the intense electron beam (with large self-fields) can be described by standard models that exclude collective effects in the response of the material. CONCLUSIONS: The measurements show that the high-energy electron beams produced by an optically injected laser-plasma accelerator can deliver high enough dose at penetration depths of interest for electron beam radiotherapy of deep-seated tumors. Many engineering issues must be resolved before laser-accelerated electrons can be used for cancer therapy, but they also represent exciting challenges for future research.

Mapping the x-ray emission region in a laser-plasma accelerator.

The x-ray emission in laser-plasma accelerators can be a powerful tool to understand the physics of relativistic laser-plasma interaction. It is shown here that the mapping of betatron x-ray radiation can be obtained from the x-ray beam profile when an aperture mask is positioned just beyond the end of the emission region. The influence of the plasma density on the position and the longitudinal profile of the x-ray emission is investigated and compared to particle-in-cell simulations. The measurement of the x-ray emission position and length provides insight on the dynamics of the interaction, including the electron self-injection region, possible multiple injection, and the role of the electron beam driven wakefield.

Observation of beam loading in a laser-plasma accelerator.

Beam loading is the phenomenon which limits the charge and the beam quality in plasma based accelerators. An experimental study conducted with a laser-plasma accelerator is presented. Beam loading manifests itself through the decrease of the beam energy, the reduction of dark current, and the increase of the energy spread for large beam charge. 3D PIC simulations are compared to the experimental results and confirm the effects of beam loading. It is found that, in our experimental conditions, the trapped electron beams generate decelerating fields on the order of 1 (GV/m)/pC and that beam loading effects are optimized for trapped charges of about 20 pC.

Controlling the phase-space volume of injected electrons in a laser-plasma accelerator.

To take full advantage of a laser-plasma accelerator, stability and control of the electron beam parameters have to be achieved. The external injection scheme with two colliding laser pulses is a way to stabilize the injection of electrons into the plasma wave, and to easily tune the energy of the output beam by changing the longitudinal position of the injection. In this Letter, it is shown that by tuning the optical injection parameters, one is able to control the phase-space volume of the injected particles, and thus the charge and the energy spread of the beam. With this method, the production of a laser accelerated electron beam of 10 pC at the 200 MeV level with a 1% relative energy spread at full width half maximum (3.1% rms) is demonstrated. This unique tunability extends the capability of laser-plasma accelerators and their applications.