Detalhe da pesquisa
1.
Monomeric α-synuclein activates the plasma membrane calcium pump.
EMBO J
; 42(23): e111122, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37916890
2.
PET imaging reveals early and progressive dopaminergic deficits after intra-striatal injection of preformed alpha-synuclein fibrils in rats.
Neurobiol Dis
; 149: 105229, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33352233
3.
Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity.
J Neuroinflammation
; 18(1): 177, 2021 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34399786
4.
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.
Acta Neuropathol
; 142(1): 87-115, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33978813
5.
Glycogen synthase kinase 3 ß activity is essential for Polo-like kinase 2- and Leucine-rich repeat kinase 2-mediated regulation of α-synuclein.
Neurobiol Dis
; 136: 104720, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31881263
6.
Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.
EMBO Rep
; 19(5)2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29599149
7.
Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death.
Neurobiol Dis
; 115: 17-28, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29501855
8.
Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production.
Neurobiol Dis
; 106: 49-62, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28648742
9.
How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro.
J Biol Chem
; 289(31): 21299-310, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24907278
10.
Characterizing the dynamics of α-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry.
Biochemistry
; 52(51): 9097-103, 2013 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24191706
11.
Sex-dimorphic neuroprotective effect of CD163 in an α-synuclein mouse model of Parkinson's disease.
NPJ Parkinsons Dis
; 9(1): 164, 2023 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092806
12.
Protein kinase R dependent phosphorylation of α-synuclein regulates its membrane binding and aggregation.
PNAS Nexus
; 1(5): pgac259, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36712380
13.
PKR kinase directly regulates tau expression and Alzheimer's disease-related tau phosphorylation.
Brain Pathol
; 31(1): 103-119, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32716602
14.
Stabilization of α-synuclein oligomers using formaldehyde.
PLoS One
; 14(10): e0216764, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31603909
15.
Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates.
Acta Neuropathol Commun
; 7(1): 213, 2019 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31856920
16.
Reduced Cytosolic Calcium as an Early Decisive Cellular State in Parkinson's Disease and Synucleinopathies.
Front Neurosci
; 12: 819, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30459551
17.
Investigation of RNA Synthesis Using 5-Bromouridine Labelling and Immunoprecipitation.
J Vis Exp
; (135)2018 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29782024
18.
ELISA method to detect α-synuclein oligomers in cell and animal models.
PLoS One
; 13(4): e0196056, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29698510
19.
Protein Partners of α-Synuclein in Health and Disease.
Brain Pathol
; 26(3): 389-97, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26940507
20.
The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins.
Structure
; 24(12): 2043-2052, 2016 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27818100