Heart rate variability in chronic low back pain patients randomized to yoga or standard care.

BACKGROUND: Chronic pain can alter the autonomic balance with increased sympathetic activity reflected in altered heart rate variability (HRV). It has been proposed that yoga can be useful to correct the autonomic imbalance in patients with chronic pain who have reduced HRV. METHODS AND DESIGNS: In the present randomized controlled trial 62 patients with chronic low back pain associated with altered alignment of intervertebral discs (aged between 20 and 45 years, 32 males) were randomized to 2 groups. One group received yoga for 3 months while the other group carried out standard medical care based on the physician's advice. The duration was the same, i.e., 3 months. The heart rate variability and rate of respiration were assessed at baseline and at the end of 3 months. RESULTS: There was a significant difference in the baseline (pre) values between groups (p = 0.008) for respiration rate which was higher in the yoga group. The changes reported below are pre-post comparisons within each group. The yoga group showed a significant (p < 0.05; repeated measures ANOVA, post-hoc analyses) decrease in the LF power of HRV, rate of respiration and a significant increase in the HF power of HRV and in the pNN50. CONCLUSION: The results suggest that yoga practice can shift the autonomic balance towards vagal dominance in patients with chronic low back pain associated with altered alignment of intervertebral discs. TRIAL REGISTRATION: The study is registered with the Clinical Trials Registry of India ( CTRI/2012/11/003094 ) and can be accessed at.

Concepts of circular economy for sustainable management of electronic wastes: challenges and management options.

The electronic and electrical industrial sector is exponentially growing throughout the globe, and sometimes, these wastes are being disposed of and discarded with a faster rate in comparison to the past era due to technology advancements. As the application of electronic devices is increasing due to the digitalization of the world (IT sector, medical, domestic, etc.), a heap of discarded e-waste is also being generated. Per-capita e-waste generation is very high in developed countries as compared to developing countries. Expansion of the global population and advancement of technologies are mainly responsible to increase the e-waste volume in our surroundings. E-waste is responsible for environmental threats as it may contain dangerous and toxic substances like metals which may have harmful effects on the biodiversity and environment. Furthermore, the life span and types of e-waste determine their harmful effects on nature, and unscientific practices of their disposal may elevate the level of threats as observed in most developing countries like India, Nigeria, Pakistan, and China. In the present review paper, many possible approaches have been discussed for effective e-waste management, such as recycling, recovery of precious metals, adopting the concepts of circular economy, formulating relevant policies, and use of advance computational techniques. On the other hand, it may also provide potential secondary resources valuable/critical materials whose primary sources are at significant supply risk. Furthermore, the use of machine learning approaches can also be useful in the monitoring and treatment/processing of e-wastes. HIGHLIGHTS: In 2019, ~ 53.6 million tons of e-wastes generated worldwide. Discarded e-wastes may be hazardous in nature due to presence of heavy metal compositions. Precious metals like gold, silver, and copper can also be procured from e-wastes. Advance tools like artificial intelligence/machine learning can be useful in the management of e-wastes.

Performance in a substitution task and state anxiety following yoga in army recruits.

140 men (M age = 30.3 yr., SD = 5.7) from the Indian army in north India participated in the study. They were naive to yoga and were assigned to yoga and breath awareness groups randomly, with 70 in each group. 20 healthy males of comparable age (M age = 33.7 yr., SD = 7.0) formed a comparison group. Their performance in a digit-letter substitution task and a state anxiety subscale was assessed immediately before and after two 45-min. sessions. The two groups of soldiers practiced either yoga or breath awareness. The comparison group listened to meditation music. Digit-letter substitution scores increased in both groups of army personnel and in the comparison group. State anxiety decreased after yoga and listening to meditation music, but not after breath awareness. This suggests that even in army personnel naive to yoga, a yoga-based intervention or listening to meditation music could reduce anxiety while increasing performance on an attention task.

Onion Peel Waste Mediated-Green Synthesis of Zinc Oxide Nanoparticles and Their Phytotoxicity on Mung Bean and Wheat Plant Growth.

Nanoparticles and nanomaterials have gained a huge amount of attention in the last decade due to their unique and remarkable properties. Metallic nanoparticles like zinc oxide nanoparticles (ZnONPs) have been used very widely as plant nutrients and in wastewater treatment. Here, ZnONPs were synthesized by using onion peel and characterized by various sophisticated instruments like Fourier transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), and field emission scanning electron microscopes (FESEM). FTIR confirmed ZnONPs synthesis due to the formation of the band in the region of 400-800 cm-1, while FESEM confirmed the spherical shape of the particles whose size varies in the range of 20-80 nm. FTIR revealed several bands from 1000-1800 cm-1 which indicates the capping by the organic molecules on the ZnONPs, which came from onion peel. It also has carbonyl and hydroxyl groups, due to the organic molecules present in the Allium cepa peel waste. The average hydrodynamic size of ZnONPs was 500 nm as confirmed by DLS. The synthesized ZnONPs were then used as a plant nutrient where their effect was evaluated on the growth of Vigna radiate (mung bean) and Triticum aestivum (wheat seeds). The results revealed that the germination and seedling of mung and wheat seeds with ZnONPs were grown better than the control seed. However, seeds of mung and wheat with ZnONPs at median concentration exposure showed an enhancement in percent germination, root, and shoot length in comparison to control. Thus, the effect of ZnONPs has been proved as a nano-based nutrient source for agricultural purposes.

Cyanobacteria as biochemical energy source for the synthesis of inorganic nanoparticles, mechanism and potential applications: a review.

Green synthesis of nanoparticles (NPs) has gained great concern among researchers due to their unique properties, excellent applications and efficient route of synthesis. From the last decades, the number biologicals such as plants, fungus, bacteria, yeast, algae, and cyanobacteria and their products are using by various researchers for the synthesis of different NPs. However, the pillar of green chemistry keeps touching new heights to improve the performance. This review paper unveils almost recent cyanobacteria-assisted greener NP synthesis technique, characterization and application. The enormous potency of cyanobacteria in NP synthesis (silver, gold, copper, zinc, palladium, titanium, cadmium sulfide, and selenium) and significance of reducing enzymes were summarized. The extracellular and intracellular entity such as metabolites, enzyme, protein, pigments in cyanobacteria play a significant role in the conversion of metal ions to metal NPs with unique properties discussed briefly. The green synthesis of nanomaterials is valuable because of their cost-effective, nontoxic and eco-friendly prospects as well as the potential application metal NPs such as antibacterial, antifungal, anticancerous, catalytic, drug delivery, bioimaging, nanopesticide, nanofertilizer, sensing properties, etc. Therefore, in the present review, we have systematically discussed the mechanisms of synthesis and applications of cyanobacteria-assisted green synthesis of NPs.

Increased Mental Well-Being and Reduced State Anxiety in Teachers After Participation in a Residential Yoga Program.

BACKGROUND Reducing stress in the workplace improves mental health. Teaching is of social importance, but it may receive inadequate recognition and rewards. The present study compared mental well-being and state anxiety in primary school teachers who practiced 15 days of yoga in a residential setting with those who continued their usual routine. MATERIAL AND METHODS We enrolled 236 primary school teachers to participate in the study. We assigned 118 primary school teachers (group mean ±S.D., age 41.5±6.0 years, 74 females) to the experimental group; they underwent 15 days of yoga training for 6 hours/day) in a residential yoga center. The non-yoga control group (group mean ±S.D., age 42.3±6.0 years, 79 females) consisted of 118 teachers who continued with their normal teaching routine. RESULTS After 15 days in the residential yoga program, there was an increase in overall mental well-being (p<.001) and lower state anxiety (p<.01) (repeated-measures ANOVA, followed by post hoc multiple comparison tests). At baseline, the non-yoga control group had higher levels of state anxiety, presumably related to their remaining in the workplace. CONCLUSIONS The study was a 15-day, comparative, controlled trial. The results show that after 15 days of participation in the residential yoga program, primary school teachers increased all aspects of mental well-being and had reduced state anxiety.

Direct sunlight enabled photo-biochemical synthesis of silver nanoparticles and their Bactericidal Efficacy: Photon energy as key for size and distribution control.

It is highly desirable to discover novel green synthesis methods for cheap and scalable synthesis of nanoparticles (NPs) to reduce the negative impact on the environment. But these approaches generally impose great challenge in controlling size, shape, and homogeneity of product NPs. Here in the present study, we report a novel approach enabling direct sunlight and oyster mushroom (Pleurotus citrinopileatus) extract for the photo-biochemical synthesis of Ag NPs. Sunlight of different wavelength was used to control the size and distribution of photo-biochemically produced NPs. Interestingly, it is observed that a smaller wavelength of sunlight produces smaller sized of NPs with a narrow size distribution. For examples; blue sunlight produces colloidal silver NPs with an average diameter of ~ 3.28 nm and 0.72 nm size distribution, while full sunlight produces comparatively larger sized (7.08 nm) NPs with wider (2.92 nm) size distribution. Since present approach uses only direct sunlight, freely available renewable energy source, a cheap biological extract as reducing and capping agent and cheap silver precursor, therefore it is an environment-friendly approach and can be used for the synthesis of NPs at industrial scale. Moreover, the size-dependent bactericidal effect has also been studied against pathogenic, Escherichia coli, bacteria. The minimum inhibitory concentration (MIC) 25 ppm and MBC 30 ppm have been observed for silver NPs of 3.28 nm average diameter.

Disc extrusions and bulges in nonspecific low back pain and sciatica: Exploratory randomised controlled trial comparing yoga therapy and normal medical treatment.

BACKGROUND: Previous trials of yoga therapy for nonspecific low back pain (nsLBP) (without sciatica) showed beneficial effects. OBJECTIVE: To test effects of yoga therapy on pain and disability associated with lumbar disc extrusions and bulges. METHODS: Parallel-group, randomised, controlled trial. Sixty-one adults from rural population, aged 20-45, with nsLBP or sciatica, and disc extrusions or bulges. Randomised to yoga (n=30) and control (n=31). Yoga: 3-month yoga course of group classes and home practice, designed to ensure safety for disc extrusions. CONTROL: normal medical care. OUTCOME MEASURES (3-4 months) Primary: Roland Morris Disability Questionnaire (RMDQ); worst pain in past two weeks. Secondary: Aberdeen Low Back Pain Scale; straight leg raise test; structural changes. RESULTS: Disc projections per case ranged from one bulge or one extrusion to three bulges plus two extrusions. Sixty-two percent had sciatica. Intention-to-treat analysis of the RMDQ data, adjusted for age, sex and baseline RMDQ scores, gave a Yoga Group score 3.29 points lower than Control Group (0.98, 5.61; p=0.006) at 3 months. No other significant differences in the endpoints occurred. No adverse effects of yoga were reported. CONCLUSIONS: Yoga therapy can be safe and beneficial for patients with nsLBP or sciatica, accompanied by disc extrusions and bulges.

Effect of yoga or physical exercise on physical, cognitive and emotional measures in children: a randomized controlled trial.

BACKGROUND: Previous studies have separately reported the effects of physical exercise and yoga in children, showing physical, cognitive and emotional benefits. OBJECTIVES: The present randomized controlled trial assessed the effects of yoga or physical exercise on physical fitness, cognitive performance, self-esteem, and teacher-rated behavior and performance, in school children. METHODS: 98 school children between 8 to 13 years were randomized as yoga and physical exercise groups {n = 49 each; (yoga: 15 girls, group mean age 10.4 ± 1.2 years), (physical exercise: 23 girls, group mean age 10.5 ± 1.3 years)}. Both groups were blind assessed after allocation, using: (i) the Eurofit physical fitness test battery, (ii) Stroop color-word task for children, (iii) Battle's self-esteem inventory and (iv) the teachers' rating of the children's obedience, academic performance, attention, punctuality, and behavior with friends and teachers. After assessments the yoga group practiced yoga (breathing techniques, postures, guided relaxation and chanting), 45 minutes each day, 5 days a week. During this time the physical exercise group had jogging-in-place, rapid repetitive movements and relay races or games. Both groups were assessed at the end of 3 months. Data were analyzed with RM ANOVA and post-hoc tests were Bonferroni adjusted. RESULTS: There was one significant difference between groups. This was in social self-esteem which was higher after physical exercise compared to yoga (p < 0.05). All the changes reported below are based on after-before comparisons, within each group. Both groups showed an increase in BMI, and number of sit-ups (p < 0.001). Balance worsened in the physical exercise group, while plate tapping improved in the yoga group (p < 0.001). In the Stroop task both groups showed improved color, word- and color-word naming (p < 0.01), while the physical exercise group showed higher interference scores. Total, general and parental self-esteem improved in the yoga group (p < 0.05). CONCLUSION: Yoga and physical exercise are useful additions to the school routine, with physical exercise improving social self-esteem. TRIAL REGISTRATION: The study was registered in the Clinical Trials Registry of India (CTRI/2012/11/003112).