Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Altered Storage and Function of von Willebrand Factor in Human Cardiac Microvascular Endothelial Cells Isolated from Recipient Transplant Hearts.

Meli, Athinoula; McCormack, Ann; Conte, Ianina; Chen, Qu; Streetley, James; Rose, Marlene L; Bierings, Ruben; Hannah, Matthew J; Molloy, Justin E; Rosenthal, Peter B; Carter, Tom.

Int J Mol Sci ; 24(5)2023 Feb 25.

Artigo em Inglês | MEDLINE | ID: mdl-36901985

2.

Platelet degranulation and bleeding phenotype in a large cohort of Von Willebrand disease patients.

Swinkels, Maurice; Atiq, Ferdows; Bürgisser, Petra E; van Moort, Iris; Meijer, Karina; Eikenboom, Jeroen; Fijnvandraat, Karin; van Galen, Karin P M; de Meris, Joke; Schols, Saskia E M; van der Bom, Johanna G; Cnossen, Marjon H; Voorberg, Jan; Leebeek, Frank W G; Bierings, Ruben; Jansen, A J Gerard.

Br J Haematol ; 197(4): 497-501, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-36165954

3.

Syntaxin 5 determines Weibel-Palade body size and von Willebrand factor secretion by controlling Golgi architecture.

Kat, Marije; Karampini, Ellie; Hoogendijk, Arie J; Bürgisser, Petra E; Mulder, Aat A; Van Alphen, Floris P J; Olins, Jenny; Geerts, Dirk; Van den Biggelaar, Maartje; Margadant, Coert; Voorberg, Jan; Bierings, Ruben.

Haematologica ; 107(8): 1827-1839, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35081689

4.

Double-Hit-Induced Leukocyte Extravasation Driven by Endothelial Adherens Junction Destabilization.

Morsing, Sofia K H; Al-Mardini, Claudia; van Stalborch, Anne-Marieke D; Schillemans, Maaike; Bierings, Ruben; Vlaar, Alexander P; van Buul, Jaap D.

J Immunol ; 205(2): 511-520, 2020 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-32532835

5.

Synaptotagmin 5 regulates Ca²⁺-dependent Weibel-Palade body exocytosis in human endothelial cells.

Lenzi, Camille; Stevens, Jennifer; Osborn, Daniel; Hannah, Matthew J; Bierings, Ruben; Carter, Tom.

J Cell Sci ; 132(5)2019 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-30659119

6.

Sec22b determines Weibel-Palade body length by controlling anterograde ER-Golgi transport.

Karampini, Ellie; Bürgisser, Petra E; Olins, Jenny; Mulder, Aat A; Jost, Carolina R; Geerts, Dirk; Voorberg, Jan; Bierings, Ruben.

Haematologica ; 106(4): 1138-1147, 2021 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-32336681

7.

Orchestration of Primary Hemostasis by Platelet and Endothelial Lysosome-Related Organelles.

Karampini, Ellie; Bierings, Ruben; Voorberg, Jan.

Arterioscler Thromb Vasc Biol ; 40(6): 1441-1453, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32375545

8.

CSI: Weibel-Palade bodies.

Bierings, Ruben; Voorberg, Jan.

Blood ; 141(8): 820-821, 2023 02 23.

Artigo em Inglês | MEDLINE | ID: mdl-36821184

9.

Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.

Karampini, Ellie; Schillemans, Maaike; Hofman, Menno; van Alphen, Floris; de Boer, Martin; Kuijpers, Taco W; van den Biggelaar, Maartje; Voorberg, Jan; Bierings, Ruben.

Haematologica ; 104(10): 2091-2099, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-30630984

10.

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

Schillemans, Maaike; Karampini, Ellie; van den Eshof, Bart L; Gangaev, Anastasia; Hofman, Menno; van Breevoort, Dorothee; Meems, Henriët; Janssen, Hans; Mulder, Aat A; Jost, Carolina R; Escher, Johanna C; Adam, Rüdiger; Carter, Tom; Koster, Abraham J; van den Biggelaar, Maartje; Voorberg, Jan; Bierings, Ruben.

Arterioscler Thromb Vasc Biol ; 38(7): 1549-1561, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29880488

11.

Interaction between MyRIP and the actin cytoskeleton regulates Weibel-Palade body trafficking and exocytosis.

Conte, Ianina L; Hellen, Nicola; Bierings, Ruben; Mashanov, Gregory I; Manneville, Jean-Baptiste; Kiskin, Nikolai I; Hannah, Matthew J; Molloy, Justin E; Carter, Tom.

J Cell Sci ; 129(3): 592-603, 2016 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-26675235

12.

A subset of anti-HLA antibodies induces FcÎ³RIIa-dependent platelet activation.

Rijkers, Maaike; Saris, Anno; Heidt, Sebastiaan; Mulder, Arend; Porcelijn, Leendert; Claas, Frans H J; Bierings, Ruben; Leebeek, Frank W G; Jansen, A J Gerard; Vidarsson, Gestur; Voorberg, Jan; de Haas, Masja.

Haematologica ; 103(10): 1741-1752, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-29858387

13.

The prion protein inhibits monocytic cell migration by stimulating ß1 integrin adhesion and uropod formation.

Richardson, Dion D; Tol, Simon; Valle-Encinas, Eider; Pleguezuelos, Cayetano; Bierings, Ruben; Geerts, Dirk; Fernandez-Borja, Mar.

J Cell Sci ; 128(16): 3018-29, 2015 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-26159734

14.

WPBs: making a mark and leaving a trail.

Carter, Tom; Bierings, Ruben.

Blood ; 134(12): 909-910, 2019 09 19.

Artigo em Inglês | MEDLINE | ID: mdl-31537537

15.

STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a.

van Breevoort, Dorothee; Snijders, Ambrosius P; Hellen, Nicola; Weckhuysen, Sarah; van Hooren, Kathinka W E M; Eikenboom, Jeroen; Valentijn, Karine; Fernandez-Borja, Mar; Ceulemans, Berten; De Jonghe, Peter; Voorberg, Jan; Hannah, Matthew; Carter, Tom; Bierings, Ruben.

Blood ; 123(20): 3185-94, 2014 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-24700782

16.

The interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis.

Bierings, Ruben; Hellen, Nicola; Kiskin, Nikolai; Knipe, Laura; Fonseca, Ana-Violeta; Patel, Bijal; Meli, Athina; Rose, Marlene; Hannah, Matthew J; Carter, Tom.

Blood ; 120(13): 2757-67, 2012 Sep 27.

Artigo em Inglês | MEDLINE | ID: mdl-22898601

17.

A new look at an old body: molecular determinants of Weibel-Palade body composition and von Willebrand factor exocytosis.

Hordijk, Sophie; Carter, Tom; Bierings, Ruben.

J Thromb Haemost ; 22(5): 1290-1303, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38307391

18.

Transcriptional and functional profiling identifies inflammation and endothelial-to-mesenchymal transition as potential drivers for phenotypic heterogeneity within a cohort of endothelial colony forming cells.

Laan, Sebastiaan N J; de Boer, Suzan; Dirven, Richard J; van Moort, Iris; Kuipers, Thomas B; Mei, Hailiang; Bierings, Ruben; Eikenboom, Jeroen.

J Thromb Haemost ; 2024 Apr 02.

Artigo em Inglês | MEDLINE | ID: mdl-38574861

19.

O-glycan determinants regulate VWF trafficking to Weibel-Palade bodies.

Karampini, Ellie; Doherty, Dearbhla; Bürgisser, Petra E; Garre, Massimiliano; Schoen, Ingmar; Elliott, Stephanie; Bierings, Ruben; O'Donnell, James S.

Blood Adv ; 8(12): 3254-3266, 2024 Jun 25.

Artigo em Inglês | MEDLINE | ID: mdl-38640438

20.

Variant mapping using mass spectrometry-based proteotyping as a diagnostic tool in von Willebrand disease.

Kreft, Iris C; van Duijl, Tirsa T; van Kwawegen, Calvin; Atiq, Ferdows; Phan, Winny; Schuller, Margo B P; Boon-Spijker, Mariëtte; van der Zwaan, Carmen; Meijer, Alexander B; Hoogendijk, Arie J; Bierings, Ruben; Eikenboom, Jeroen C J; Leebeek, Frank W G; van den Biggelaar, Maartje.

J Thromb Haemost ; 2024 Apr 27.

Artigo em Inglês | MEDLINE | ID: mdl-38679335

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