Detalhe da pesquisa
1.
JNJ-73763989 and bersacapavir treatment in nucleos(t)ide analog suppressed patients with chronic hepatitis B: REEF-2.
J Hepatol
; 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38583491
2.
Randomised phase 2 study (JADE) of the HBV capsid assembly modulator JNJ-56136379 with or without a nucleos(t)ide analogue in patients with chronic hepatitis B infection.
Gut
; 72(7): 1385-1398, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36697207
3.
A case of HBV-induced liver failure in the REEF-2 phase II trial: Implications for finite treatment strategies in HBV 'cure'.
J Hepatol
; 77(1): 245-248, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35358614
4.
Combination treatments including the small-interfering RNA JNJ-3989 induce rapid and sometimes prolonged viral responses in patients with CHB.
J Hepatol
; 77(5): 1287-1298, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35870702
5.
JNJ-4178 (AL-335, Odalasvir, and Simeprevir) for 6 or 8 Weeks in Hepatitis C Virus-Infected Patients Without Cirrhosis: OMEGA-1.
Hepatology
; 69(6): 2349-2363, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30693573
6.
Improved pharmacodynamics and pharmacokinetics after i.v. application of peginterferon alfa-2a in hepatitis C null responders.
Liver Int
; 35(10): 2275-84, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25801095
7.
Viral sequence analysis of chronic hepatitis B patients treated with the capsid assembly modulator JNJ-56136379 in the JADE phase 2a study.
Antiviral Res
; 216: 105660, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37385475
8.
Pharmacokinetics of JNJ-73763989 and JNJ-56136379 (Bersacapavir) in Participants With Moderate Hepatic Impairment.
J Clin Pharmacol
; 63(6): 732-741, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36786053
9.
Pharmacokinetics, Safety, and Tolerability of the siRNA JNJ-73763989 in Healthy Chinese Adult Participants.
Clin Pharmacol Drug Dev
; 12(2): 175-180, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36415122
10.
Efficacy and safety of the siRNA JNJ-73763989 and the capsid assembly modulator JNJ-56136379 (bersacapavir) with nucleos(t)ide analogues for the treatment of chronic hepatitis B virus infection (REEF-1): a multicentre, double-blind, active-controlled, randomised, phase 2b trial.
Lancet Gastroenterol Hepatol
; 8(9): 790-802, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37442152
11.
Drug-Drug Interactions With the Hepatitis B Virus Capsid Assembly Modulator JNJ-56136379 (Bersacapavir).
Clin Pharmacol Drug Dev
; 11(12): 1419-1429, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36062869
12.
JNJ-73763989 pharmacokinetics and safety: Liver-targeted siRNAs against hepatitis B virus, in Japanese and non-Japanese healthy adults, and combined with JNJ-56136379 and a nucleos(t)ide analogue in patients with chronic hepatitis B.
Antivir Ther
; 27(3): 13596535221093856, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35695169
13.
Viscoelasticity-based staging of hepatic fibrosis with multifrequency MR elastography.
Radiology
; 257(1): 80-6, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20679447
14.
JNJ-4178 (adafosbuvir, odalasvir, and simeprevir) in Japanese patients with chronic hepatitis C virus genotype 1 or 2 infection with or without compensated cirrhosis: the Phase IIa OMEGA-3 study.
J Gastroenterol
; 55(6): 640-652, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32065330
15.
Rapid suppression of hepatitis C viremia induced by intravenous silibinin plus ribavirin.
Gastroenterology
; 137(1): 390-1, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19486953
16.
A Preliminary Study on the Relationship between Platelet Serotonin Transporter Functionality, Depression, and Fatigue in Patients with Untreated Chronic Hepatitis C.
Depress Res Treat
; 2014: 821381, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24778869
17.
Treatment of hepatitis C-virus-reinfection after liver transplant with silibinin in nonresponders to pegylated interferon-based therapy.
Exp Clin Transplant
; 9(1): 1-6, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21605016
18.
The GNB3 C825T polymorphism affects response to HCV therapy with pegylated interferon in HCV/HIV co-infected but not in HCV mono-infected patients.
J Hepatol
; 47(3): 348-55, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17559964
19.
Tumor necrosis factor alpha inhibition of hepatitis B virus replication involves disruption of capsid Integrity through activation of NF-kappaB.
J Virol
; 77(7): 4033-42, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12634363