[Interactions between naltrexone, an opioid antagonist, and opioids administered during general anesthesia]. / Interférences entre la naltrexone, un antagoniste des morphiniques, et les morphiniques administrés pendant une anesthésie générale.

We report a case of a probable interaction between sufentanil and naltrexone, an oral long acting opioid antagonist, prescribed for maintenance of abstinence in alcoholics and opioid addicts. The interaction resulted in an antagonisation of the effects of sufentanil and the necessity to increase the dosage. Anaesthetists should be aware of this potential drug interaction.