Detalhe da pesquisa
1.
In vivo CRISPR editing with no detectable genome-wide off-target mutations.
Nature
; 561(7723): 416-419, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30209390
2.
Allostatic hypermetabolic response in PGC1α/ß heterozygote mouse despite mitochondrial defects.
FASEB J
; 35(9): e21752, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34369602
3.
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model.
BMC Biol
; 17(1): 4, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30646909
4.
Cardiac-Specific Overexpression of Oxytocin Receptor Leads to Cardiomyopathy in Mice.
J Card Fail
; 24(7): 470-478, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29802896
5.
Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet.
Am J Physiol Endocrinol Metab
; 300(1): E211-20, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20959533
6.
Ghrelin increases intake of rewarding food in rodents.
Addict Biol
; 15(3): 304-11, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20477752
7.
Review article: the emerging role of genetics in precision medicine for patients with non-alcoholic steatohepatitis.
Aliment Pharmacol Ther
; 51(12): 1305-1320, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32383295
8.
Central NMU signaling in body weight and energy balance regulation: evidence from NMUR2 deletion and chronic central NMU treatment in mice.
Am J Physiol Endocrinol Metab
; 297(3): E708-16, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19584200
9.
Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.
PLoS Biol
; 4(11): e369, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17090215
10.
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice.
Mol Metab
; 22: 49-61, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30772256
11.
IDOL regulates systemic energy balance through control of neuronal VLDLR expression.
Nat Metab
; 1(11): 1089-1100, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32072135
12.
Opposing effects of adiponectin receptors 1 and 2 on energy metabolism.
Diabetes
; 56(3): 583-93, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17327425
13.
Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype.
EBioMedicine
; 29: 104-111, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29500128
14.
Melanin-concentrating hormone receptor 1 deficiency increases insulin sensitivity in obese leptin-deficient mice without affecting body weight.
Diabetes
; 55(3): 725-33, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16505236
15.
Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia.
Diabetes
; 54(1): 51-62, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15616010
16.
Deletion of Gpr55 Results in Subtle Effects on Energy Metabolism, Motor Activity and Thermal Pain Sensation.
PLoS One
; 11(12): e0167965, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27941994
17.
Lingonberries alter the gut microbiota and prevent low-grade inflammation in high-fat diet fed mice.
Food Nutr Res
; 60: 29993, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27125264
18.
Retinoid-related orphan receptor γ (RORγ) adult induced knockout mice develop lymphoblastic lymphoma.
Autoimmun Rev
; 15(11): 1062-1070, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27491564
19.
Effects of a novel potent melanin-concentrating hormone receptor 1 antagonist, AZD1979, on body weight homeostasis in mice and dogs.
Br J Pharmacol
; 173(18): 2739-51, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27400775
20.
Inhibition of AMP deaminase activity does not improve glucose control in rodent models of insulin resistance or diabetes.
Chem Biol
; 21(11): 1486-96, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25459661