Detalhe da pesquisa
1.
In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor.
Antimicrob Agents Chemother
; 66(12): e0092122, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36448795
2.
The Aging, Community and Health Research Unit Community Partnership Program (ACHRU-CPP) for older adults with diabetes and multiple chronic conditions: study protocol for a randomized controlled trial.
BMC Geriatr
; 22(1): 99, 2022 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35120457
3.
A First-in-Human Study To Assess the Safety and Pharmacokinetics of LYS228, a Novel Intravenous Monobactam Antibiotic in Healthy Volunteers.
Antimicrob Agents Chemother
; 63(7)2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31061156
4.
Impact of Inducible blaDHA-1 on Susceptibility of Klebsiella pneumoniae Clinical Isolates to LYS228 and Identification of Chromosomal mpl and ampD Mutations Mediating Upregulation of Plasmid-Borne blaDHA-1 Expression.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061296
5.
In Vitro Activity of LYS228, a Novel Monobactam Antibiotic, against Multidrug-Resistant Enterobacteriaceae.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30038040
6.
Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061293
7.
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.
Bioorg Med Chem Lett
; 28(4): 748-755, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29336873
8.
Multicenter, randomized clinical trial to compare the safety and efficacy of LFF571 and vancomycin for Clostridium difficile infections.
Antimicrob Agents Chemother
; 59(3): 1435-40, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25534727
9.
Antistaphylococcal activity of TD-1792, a multivalent glycopeptide-cephalosporin antibiotic.
Antimicrob Agents Chemother
; 56(3): 1584-7, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22203585
10.
Pharmacodynamics of TD-1792, a novel glycopeptide-cephalosporin heterodimer antibiotic used against Gram-positive bacteria, in a neutropenic murine thigh model.
Antimicrob Agents Chemother
; 56(3): 1578-83, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22155835
11.
Opportunities and Challenges in Developing a Cryptosporidium Controlled Human Infection Model for Testing Antiparasitic Agents.
ACS Infect Dis
; 7(5): 959-968, 2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33822577
12.
Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria.
J Med Chem
; 64(9): 6329-6357, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33929852
13.
Specificity of induction of the vanA and vanB operons in vancomycin-resistant enterococci by telavancin.
Antimicrob Agents Chemother
; 54(7): 2814-8, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20404117
14.
Activity of telavancin against heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) in vitro and in an in vivo mouse model of bacteraemia.
J Antimicrob Chemother
; 65(4): 725-8, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20139142
15.
IID572: A New Potentially Best-In-Class ß-Lactamase Inhibitor.
ACS Infect Dis
; 5(7): 1045-1051, 2019 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30861342
16.
Novel antibacterial azetidine lincosamides.
Bioorg Med Chem Lett
; 18(8): 2645-8, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18359228
17.
Can patients be trained to expect shared decision making in clinical consultations? Feasibility study of a public library program to raise patient awareness.
PLoS One
; 13(12): e0208449, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30540833
18.
Playing cards on asthma management: a new interactive method for knowledge transfer to primary care physicians.
Can Respir J
; 14(8): 480-4, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18060093
19.
Primary health care professionals' views on barriers and facilitators to the implementation of the Ottawa Decision Support Framework in practice.
Patient Educ Couns
; 63(3): 380-90, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17010555
20.
Family physicians' intention to support women in making informed decisions about breast cancer screening with mammography: a cross-sectional survey.
BMC Res Notes
; 8: 663, 2015 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26555569