Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Metabolic alterations of the immune system in the pathogenesis of autoimmune diseases.

Blanco, Luz P; Kaplan, Mariana J.

PLoS Biol ; 21(4): e3002084, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-37098006

2.

Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus.

Goel, Rishi R; Wang, Xinghao; O'Neil, Liam J; Nakabo, Shuichiro; Hasneen, Kowser; Gupta, Sarthak; Wigerblad, Gustaf; Blanco, Luz P; Kopp, Jeffrey B; Morasso, Maria I; Kotenko, Sergei V; Yu, Zu-Xi; Carmona-Rivera, Carmelo; Kaplan, Mariana J.

Proc Natl Acad Sci U S A ; 117(10): 5409-5419, 2020 03 10.

Artigo em Inglês | MEDLINE | ID: mdl-32094169

3.

Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism.

Gupta, Sarthak; Nakabo, Shuichiro; Blanco, Luz P; O'Neil, Liam J; Wigerblad, Gustaf; Goel, Rishi R; Mistry, Pragnesh; Jiang, Kan; Carmona-Rivera, Carmelo; Chan, Diana W; Wang, Xinghao; Pedersen, Hege L; Gadkari, Manasi; Howe, Katherine N; Naz, Faiza; Dell'Orso, Stefania; Hasni, Sarfaraz A; Dempsey, Caeden; Buscetta, Ashley; Frischmeyer-Guerrerio, Pamela A; Kruszka, Paul; Muenke, Maximilian; Franco, Luis M; Sun, Hong-Wei; Kaplan, Mariana J.

Proc Natl Acad Sci U S A ; 117(28): 16481-16491, 2020 07 14.

Artigo em Inglês | MEDLINE | ID: mdl-32601182

4.

Metabolic abnormalities and oxidative stress in lupus.

Lightfoot, Yaima L; Blanco, Luz P; Kaplan, Mariana J.

Curr Opin Rheumatol ; 29(5): 442-449, 2017 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-28639951

5.

Distinct pathways of humoral and cellular immunity induced with the mucosal administration of a nanoemulsion adjuvant.

Bielinska, Anna U; Makidon, Paul E; Janczak, Katarzyna W; Blanco, Luz P; Swanson, Benjamin; Smith, Douglas M; Pham, Tiffany; Szabo, Zsuzsanna; Kukowska-Latallo, Jolanta F; Baker, James R.

J Immunol ; 192(6): 2722-33, 2014 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-24532579

6.

Iron induces bimodal population development by Escherichia coli.

DePas, William H; Hufnagel, David A; Lee, John S; Blanco, Luz P; Bernstein, Hans C; Fisher, Steve T; James, Garth A; Stewart, Philip S; Chapman, Matthew R.

Proc Natl Acad Sci U S A ; 110(7): 2629-34, 2013 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-23359678

7.

Murine norovirus transcytosis across an in vitro polarized murine intestinal epithelial monolayer is mediated by M-like cells.

Gonzalez-Hernandez, Mariam B; Liu, Thomas; Blanco, Luz P; Auble, Heather; Payne, Hilary C; Wobus, Christiane E.

J Virol ; 87(23): 12685-93, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24049163

8.

The aconitate decarboxylase 1/itaconate pathway modulates immune dysregulation and associates with cardiovascular disease markers in SLE.

Patiño-Martinez, Eduardo; Nakabo, Shuichiro; Jiang, Kan; Carmona-Rivera, Carmelo; Tsai, Wanxia Li; Claybaugh, Dillon; Yu, Zu-Xi; Romero, Aracely; Bohrnsen, Eric; Schwarz, Benjamin; Solís-Barbosa, Miguel A; Blanco, Luz P; Naqi, Mohammad; Temesgen-Oyelakim, Yenealem; Davis, Michael; Manna, Zerai; Mehta, Nehal; Naz, Faiza; Brooks, Stephen; dell'Orso, Stefania; Hasni, Sarfaraz; Kaplan, Mariana J.

medRxiv ; 2024 Feb 22.

Artigo em Inglês | MEDLINE | ID: mdl-38605883

9.

Nanoemulsion mucosal adjuvant uniquely activates cytokine production by nasal ciliated epithelium and induces dendritic cell trafficking.

Makidon, Paul E; Belyakov, Igor M; Blanco, Luz P; Janczak, Katarzyna W; Landers, Jeffrey; Bielinska, Anna U; Groom, Jeffrey V; Baker, James R.

Eur J Immunol ; 42(8): 2073-86, 2012 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-22653620

10.

Modulation of the Itaconate Pathway Attenuates Murine Lupus.

Blanco, Luz P; Patino-Martinez, Eduardo; Nakabo, Shuichiro; Zhang, Mingzeng; Pedersen, Hege L; Wang, Xinghao; Carmona-Rivera, Carmelo; Claybaugh, Dillon; Yu, Zu-Xi; Desta, Equar; Kaplan, Mariana J.

Arthritis Rheumatol ; 74(12): 1971-1983, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-35791960

11.

Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes.

Wu, Jing; Singh, Komudi; Lin, Amy; Meadows, Allison M; Wu, Kaiyuan; Shing, Vivian; Bley, Maximilian; Hassanzadeh, Shahin; Huffstutler, Rebecca D; Schmidt, Mark S; Blanco, Luz P; Tian, Rong; Brenner, Charles; Pirooznia, Mehdi; Kaplan, Mariana J; Sack, Michael N.

J Clin Invest ; 132(5)2022 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-35025762

12.

Induction of Th17 cellular immunity with a novel nanoemulsion adjuvant.

Bielinska, Anna U; Gerber, Michele; Blanco, Luz P; Makidon, Paul E; Janczak, Katarzyna W; Beer, Michael; Swanson, Benjamin; Baker, James R.

Crit Rev Immunol ; 30(2): 189-99, 2010.

Artigo em Inglês | MEDLINE | ID: mdl-20370629

13.

RNA Externalized by Neutrophil Extracellular Traps Promotes Inflammatory Pathways in Endothelial Cells.

Blanco, Luz P; Wang, Xinghao; Carlucci, Philip M; Torres-Ruiz, Jose Jiram; Romo-Tena, Jorge; Sun, Hong-Wei; Hafner, Markus; Kaplan, Mariana J.

Arthritis Rheumatol ; 73(12): 2282-2292, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-33983685

14.

Effects of Gasdermin D in Modulating Murine Lupus and its Associated Organ Damage.

Wang, Xinghao; Blanco, Luz P; Carmona-Rivera, Carmelo; Nakabo, Shuichiro; Pedersen, Hege L; Yu, Zu-Xi; Kaplan, Mariana J.

Arthritis Rheumatol ; 72(12): 2118-2129, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-32692482

15.

Improved Mitochondrial Metabolism and Reduced Inflammation Following Attenuation of Murine Lupus With Coenzyme Q10 Analog Idebenone.

Blanco, Luz P; Pedersen, Hege L; Wang, Xinghao; Lightfoot, Yaíma L; Seto, Nickie; Carmona-Rivera, Carmelo; Yu, Zu-Xi; Hoffmann, Victoria; Yuen, Peter S T; Kaplan, Mariana J.

Arthritis Rheumatol ; 72(3): 454-464, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31566908

16.

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice.

Fortner, Karen A; Blanco, Luz P; Buskiewicz, Iwona; Huang, Nick; Gibson, Pamela C; Cook, Deborah L; Pedersen, Hege L; Yuen, Peter S T; Murphy, Michael P; Perl, Andras; Kaplan, Mariana J; Budd, Ralph C.

Lupus Sci Med ; 7(1)2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-32343673

17.

Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model.

Tumurkhuu, Gantsetseg; Chen, Shuang; Montano, Erica N; Ercan Laguna, Duygu; De Los Santos, Gabriela; Yu, Jeong Min; Lane, Malcolm; Yamashita, Michifumi; Markman, Janet L; Blanco, Luz P; Kaplan, Mariana J; Shimada, Kenichi; Crother, Timothy R; Ishimori, Mariko; Wallace, Daniel J; Jefferies, Caroline A; Arditi, Moshe.

Front Immunol ; 11: 554725, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-33072095

18.

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease.

Kim, Jeonghan; Gupta, Rajeev; Blanco, Luz P; Yang, Shutong; Shteinfer-Kuzmine, Anna; Wang, Kening; Zhu, Jun; Yoon, Hee Eun; Wang, Xinghao; Kerkhofs, Martijn; Kang, Hyeog; Brown, Alexandra L; Park, Sung-Jun; Xu, Xihui; Zandee van Rilland, Eddy; Kim, Myung K; Cohen, Jeffrey I; Kaplan, Mariana J; Shoshan-Barmatz, Varda; Chung, Jay H.

Science ; 366(6472): 1531-1536, 2019 12 20.

Artigo em Inglês | MEDLINE | ID: mdl-31857488

19.

Reply.

Blanco, Luz P; Kaplan, Mariana J.

Arthritis Rheumatol ; 75(1): 143-144, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-35969518

20.

Proteins of generalist and specialist pathogens differ in their amino acid composition.

Blanco, Luz P; Payne, Bryan L; Feyertag, Felix; Alvarez-Ponce, David.

Life Sci Alliance ; 1(4): e201800017, 2018 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-30456362

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