Detalhe da pesquisa
1.
Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AML.
Blood
; 143(15): 1513-1527, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096371
2.
An evolutionary model encompassing substrate specificity and reactivity of type I polyketide synthase thioesterases.
Chembiochem
; 15(18): 2656-61, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25354333
3.
CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype Specific Vulnerability in IDH2- and TET2-Mutant Cells.
Cancer Discov
; 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38819218
4.
Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.
Nat Commun
; 13(1): 1898, 2022 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35393414
5.
Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation.
J Exp Clin Cancer Res
; 38(1): 251, 2019 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31196146
6.
Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness.
Nat Commun
; 10(1): 2891, 2019 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31253791
7.
Leukemic stem cell signatures identify novel therapeutics targeting acute myeloid leukemia.
Blood Cancer J
; 8(6): 52, 2018 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29921955
8.
Complement cascade gene expression defines novel prognostic subgroups of acute myeloid leukemia.
Exp Hematol
; 44(11): 1039-1043.e10, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27473565
9.
Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
Nat Med
; 21(5): 530-6, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25894825