Detalhe da pesquisa
1.
Structural and Mechanistic Insights into the Transport of Aristolochic Acids and their Active Metabolites by Human Serum Albumin.
J Biol Chem
; : 107358, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38782206
2.
Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AαC) in human bladder RT4 cells.
Arch Toxicol
; 93(7): 1893-1902, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31203411
3.
Targeted and Untargeted Detection of DNA Adducts of Aromatic Amine Carcinogens in Human Bladder by Ultra-Performance Liquid Chromatography-High-Resolution Mass Spectrometry.
Chem Res Toxicol
; 31(12): 1382-1397, 2018 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30387604
4.
Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells.
Carcinogenesis
; 37(7): 647-655, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27207664
5.
Total synthesis of the aristolochic acids, their major metabolites, and related compounds.
Chem Res Toxicol
; 27(7): 1236-42, 2014 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24877584
6.
Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts.
Nucleic Acids Res
; 40(6): 2494-505, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22121226
7.
Mechanisms of antiviral action and toxicities of ipecac alkaloids: Emetine and dehydroemetine exhibit anti-coronaviral activities at non-cardiotoxic concentrations.
Virus Res
; 341: 199322, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38228190
8.
Biomonitoring of aristolactam-DNA adducts in human tissues using ultra-performance liquid chromatography/ion-trap mass spectrometry.
Chem Res Toxicol
; 25(5): 1119-31, 2012 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22515372
9.
DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells.
Nucleic Acids Res
; 38(1): 339-52, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19854934
10.
Characterization of Aurintricarboxylic Acid (ATA) Interactions with Plasma Transporter Protein and SARS-CoV-2 Viral Targets: Correlation of Functional Activity and Binding Energetics.
Life (Basel)
; 12(6)2022 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35743905
11.
Glutamate dehydrogenase requirement for apoptosis induced by aristolochic acid in renal tubular epithelial cells.
Apoptosis
; 16(12): 1217-28, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21901531
12.
Physiological and molecular characterization of aristolochic acid transport by the kidney.
J Pharmacol Exp Ther
; 338(2): 588-97, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21546538
13.
Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents.
Int J Cancer
; 127(5): 1021-7, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20039324
14.
The steric gate amino acid tyrosine 112 is required for efficient mismatched-primer extension by human DNA polymerase kappa.
Biochemistry
; 48(20): 4239-46, 2009 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19341290
15.
Bioactivation mechanisms of N-hydroxyaristolactams: Nitroreduction metabolites of aristolochic acids.
Environ Mol Mutagen
; 60(9): 792-806, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31374128
16.
Y-family DNA polymerase-independent gap-filling translesion synthesis across aristolochic acid-derived adenine adducts in mouse cells.
DNA Repair (Amst)
; 46: 55-60, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27497692
17.
Mutagenic specificity of 2-acetylaminonaphthalene-derived DNA adduct in mammalian cells.
Chem Biol Interact
; 152(2-3): 131-8, 2005 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15840386
18.
Synthesis of the fully protected phosphoramidite of the benzene-DNA adduct, N2-(4-Hydroxyphenyl)-2'-deoxyguanosine and incorporation of the later into DNA oligomers.
Nucleosides Nucleotides Nucleic Acids
; 27(8): 979-91, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18696366
19.
Synthesis of the PhIP adduct of 2'-deoxyguanosine and its incorporation into oligomeric DNA.
Chem Res Toxicol
; 19(6): 734-8, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16780350
20.
Structure and stability of duplex DNA containing the 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene (dG(N2)-AAF) lesion: a bulky adduct that persists in cellular DNA.
Chem Res Toxicol
; 19(6): 745-52, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16780352