Detalhe da pesquisa
1.
Synthesis, carbonic anhydrase inhibition studies and modelling investigations of phthalimide-hydantoin hybrids.
J Enzyme Inhib Med Chem
; 39(1): 2335927, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38606915
2.
Sulfonamide-incorporated bis(α-aminophosphonates) as promising carbonic anhydrase inhibitors: Design, synthesis, biological evaluation, and X-ray crystallographic studies.
Arch Pharm (Weinheim)
; : e2400038, 2024 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38498884
3.
Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains.
Int J Mol Sci
; 25(5)2024 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38473830
4.
Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies.
Bioorg Med Chem
; 94: 117467, 2023 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37722299
5.
4-Cyanamido-substituted benzenesulfonamides act as dual carbonic anhydrase and cathepsin inhibitors.
Bioorg Chem
; 139: 106725, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37442043
6.
Arylidine extensions of 3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-benzenesulfonamide derivatives: Synthesis, computational simulations and biological evaluation as tumor-associated carbonic anhydrase inhibitors.
Bioorg Chem
; 135: 106492, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37001471
7.
Diversely N-substituted benzenesulfonamides dissimilarly bind to human carbonic anhydrases: crystallographic investigations of N-nitrosulfonamides.
J Enzyme Inhib Med Chem
; 38(1): 2178430, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36798036
8.
Investigation of novel alkyl/benzyl (4-sulphamoylphenyl)carbamimidothioates as carbonic anhydrase inhibitors.
J Enzyme Inhib Med Chem
; 38(1): 2152811, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36629134
9.
4-Cyanamidobenzenesulfonamide derivatives: a novel class of human and bacterial carbonic anhydrase inhibitors.
J Enzyme Inhib Med Chem
; 38(1): 156-165, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36305288
10.
Discovery of the first-in-class potent and isoform-selective human carbonic anhydrase III inhibitors.
J Enzyme Inhib Med Chem
; 38(1): 2202360, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37092262
11.
Sulphonamide inhibition studies of the ß-carbonic anhydrase GsaCAß present in the salmon platyhelminth parasite Gyrodactylus salaris.
J Enzyme Inhib Med Chem
; 38(1): 2167988, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36647786
12.
Selenium-analogs based on natural sources as cancer-associated carbonic anhydrase isoforms IX and XII inhibitors.
J Enzyme Inhib Med Chem
; 38(1): 2191165, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36938694
13.
Synthesis, biological evaluation and theoretical studies of (E)-1-(4-sulfamoyl-phenylethyl)-3-arylidene-5-aryl-1H-pyrrol-2(3H)-ones as human carbonic anhydrase inhibitors.
J Enzyme Inhib Med Chem
; 38(1): 2189126, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36950918
14.
Effect of hydrophobic extension of aryl enaminones and pyrazole-linked compounds combined with sulphonamide, sulfaguanidine, or carboxylic acid functionalities on carbonic anhydrase inhibitory potency and selectivity.
J Enzyme Inhib Med Chem
; 38(1): 2201403, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37078174
15.
Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights.
J Enzyme Inhib Med Chem
; 38(1): 2201407, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37078173
16.
6-Aminocoumarin oxime-ether/sulfonamides as selective hCA IX and XII inhibitors: Synthesis, evaluation, and molecular dynamics studies.
Arch Pharm (Weinheim)
; 356(10): e2300316, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37495909
17.
Exploration of 3-aryl pyrazole-tethered sulfamoyl carboxamides as carbonic anhydrase inhibitors.
Arch Pharm (Weinheim)
; 356(11): e2300309, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37691073
18.
Inhibition Studies on Human and Mycobacterial Carbonic Anhydrases with N-((4-Sulfamoylphenyl)carbamothioyl) Amides.
Molecules
; 28(10)2023 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37241761
19.
Calixarenes Incorporating Sulfonamide Moieties: Versatile Ligands for Carbonic Anhydrases Inhibition.
Chemistry
; 28(6): e202103527, 2022 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34882858
20.
Inhibition studies of the protozoan α-carbonic anhydrase from Trypanosoma cruzi with phenols.
J Enzyme Inhib Med Chem
; 37(1): 2417-2422, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36065959