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1.
Neurol Sci ; 31(6): 793-7, 2010 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-20517703

RESUMO

Intravascular lymphomatosis (IVL) is a rare, malignant B- or T-cell lymphoma with remarkable affinity for the endothelial cells of small vessels, particularly within the skin and central nervous system. It is a disease that mimics several neurological disorders, particularly those of cerebrovascular ischemic origin. The prognosis is generally poor, with a rapidly fatal outcome. As a result the diagnosis is often made at post-mortem. We report a rare case of a 73-year-old patient with IVL complicated by intracerebral haemorrhage. In literature two cases of systemic IVL complicated by intracerebral haemorrhage have been reported, but they presented initially with a disseminated intravascular coagulation (DIC). This is the first case of brain IVL complicated by intracerebral haemorrhage not associated to DIC. Increasing awareness of this disease as a differential diagnosis to a common clinical presentation may lead to more opportunities to evaluate new diagnostic and treatment approaches.


Assuntos
Neoplasias Encefálicas/diagnóstico , Hemorragia Cerebral/diagnóstico , Linfoma de Células B/diagnóstico , Idoso , Neoplasias Encefálicas/complicações , Neoplasias Encefálicas/diagnóstico por imagem , Hemorragia Cerebral/diagnóstico por imagem , Hemorragia Cerebral/etiologia , Diagnóstico Diferencial , Evolução Fatal , Humanos , Linfoma de Células B/complicações , Linfoma de Células B/diagnóstico por imagem , Masculino , Radiografia
3.
J Clin Neurosci ; 14(10): 984-6, 2007 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17669656

RESUMO

Spinal cavernous angiomas are rare vascular malformations occurring mainly in the vertebral body with or without an extradural extension. Only 3-5% of these lesions are entirely located in the spinal canal where they can occupy an extradural, intradural-extramedullary or intramedullary position. We present a 75-year-old woman with signs and symptoms of multiple lumbar radiculopathy. The lumbosacral MRI showed an intradural cauda equina lesion with heterogeneous contrast enhancement that was subsequently radically removed through an L3-L4 laminectomy. The microscopic appearance was suggestive of cavernous angioma with intraneural growth. Clinical, radiological, and surgical features of this unusual lesion (to date, only 12 cases are reported) are discussed.


Assuntos
Cauda Equina/patologia , Hemangioma Cavernoso do Sistema Nervoso Central/complicações , Hemangioma Cavernoso do Sistema Nervoso Central/patologia , Polirradiculopatia/etiologia , Polirradiculopatia/patologia , Idoso , Vasos Sanguíneos/patologia , Vasos Sanguíneos/fisiopatologia , Cauda Equina/fisiopatologia , Cauda Equina/cirurgia , Descompressão Cirúrgica , Feminino , Hemangioma Cavernoso do Sistema Nervoso Central/fisiopatologia , Humanos , Laminectomia , Vértebras Lombares/patologia , Vértebras Lombares/fisiopatologia , Vértebras Lombares/cirurgia , Imageamento por Ressonância Magnética , Polirradiculopatia/fisiopatologia , Radiculopatia/etiologia , Radiculopatia/patologia , Radiculopatia/fisiopatologia , Canal Medular/patologia , Canal Medular/fisiopatologia , Canal Medular/cirurgia
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