Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Vascular endothelial profilin-1 drives a protumorigenic tumor microenvironment and tumor progression in renal cancer.

Gau, David; Daoud, Andrew; Allen, Abigail; Joy, Marion; Sagan, April; Lee, Sanghoon; Lucas, Peter C; Duensing, Stefan; Boone, David; Osmanbeyoglu, Hatice U; Roy, Partha.

J Biol Chem ; 299(8): 105044, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37451478

2.

STAT5 Represses a STAT3-Independent Th17-like Program during Th9 Cell Differentiation.

Canaria, D Alejandro; Yan, Bingyu; Clare, Maia G; Zhang, Zonghao; Taylor, Grace A; Boone, David L; Kazemian, Majid; Olson, Matthew R.

J Immunol ; 207(5): 1265-1274, 2021 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-34348976

3.

Reclassification of Treatment Strategy with Fractional Flow Reserve in Cancer Patients with Coronary Artery Disease.

Kim, Jin Wan; Dayah, Tariq J; Javaid, Awad; Monlezun, Dominique J; Balanescu, Dinu V; Donisan, Teodora; Karimzad, Kaveh; Hakeem, Abdul; Boone, David L; Palaskas, Nicolas; Lopez-Mattei, Juan; Kim, Peter Y; Durand, Jean-Bernard; Song, Juhee; Balanescu, Serban M; Yang, Eric H; Herrmann, Joerg; Marmagkiolis, Konstantinos; Toutouzas, Konstantinos; Johnson, Nils P; Iliescu, Cezar A.

Medicina (Kaunas) ; 58(7)2022 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-35888603

4.

Disruption of profilin1 function suppresses developmental and pathological retinal neovascularization.

Gau, David; Vignaud, Lucile; Allen, Abigail; Guo, Zhijian; Sahel, Jose; Boone, David; Koes, David; Guillonneau, Xavier; Roy, Partha.

J Biol Chem ; 295(28): 9618-9629, 2020 07 10.

Artigo em Inglês | MEDLINE | ID: mdl-32444495

5.

Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death.

Garcia-Carbonell, Ricard; Wong, Jerry; Kim, Ju Youn; Close, Lisa Abernathy; Boland, Brigid S; Wong, Thomas L; Harris, Philip A; Ho, Samuel B; Das, Soumita; Ernst, Peter B; Sasik, Roman; Sandborn, William J; Bertin, John; Gough, Pete J; Chang, John T; Kelliher, Michelle; Boone, David; Guma, Monica; Karin, Michael.

Proc Natl Acad Sci U S A ; 115(39): E9192-E9200, 2018 09 25.

Artigo em Inglês | MEDLINE | ID: mdl-30209212

6.

Effects of Manganese Porphyrins on Cellular Sulfur Metabolism.

Olson, Kenneth R; Gao, Yan; Steiger, Andrea K; Pluth, Michael D; Tessier, Charles R; Markel, Troy A; Boone, David; Stahelin, Robert V; Batinic-Haberle, Ines; Straubg, Karl D.

Molecules ; 25(4)2020 Feb 22.

Artigo em Inglês | MEDLINE | ID: mdl-32098303

7.

Controlled dimerization of insulin-like growth factor-1 and insulin receptors reveals shared and distinct activities of holo and hybrid receptors.

Chen, Jingci; Nagle, Alison M; Wang, Yu-Fen; Boone, David N; Lee, Adrian V.

J Biol Chem ; 293(10): 3700-3709, 2018 03 09.

Artigo em Inglês | MEDLINE | ID: mdl-29330302

8.

Distribution of health facilities in Nigeria: Implications and options for Universal Health Coverage.

Makinde, Olusesan Ayodeji; Sule, Abayomi; Ayankogbe, Olayinka; Boone, David.

Int J Health Plann Manage ; 33(4): e1179-e1192, 2018 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-30091473

9.

The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon.

Grimm, Wesley A; Messer, Jeannette S; Murphy, Stephen F; Nero, Thomas; Lodolce, James P; Weber, Christopher R; Logsdon, Mark F; Bartulis, Sarah; Sylvester, Brooke E; Springer, Amanda; Dougherty, Urszula; Niewold, Timothy B; Kupfer, Sonia S; Ellis, Nathan; Huo, Dezheng; Bissonnette, Marc; Boone, David L.

Gut ; 65(3): 456-64, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25645662

10.

Soluble bioactive microbial mediators regulate proteasomal degradation and autophagy to protect against inflammation-induced stress.

Inaba, Yuhei; Ueno, Nobuhiro; Numata, Masatsugu; Zhu, Xiaorong; Messer, Jeannette S; Boone, David L; Fujiya, Mikihiro; Kohgo, Yutaka; Musch, Mark W; Chang, Eugene B.

Am J Physiol Gastrointest Liver Physiol ; 311(4): G634-G647, 2016 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-27514476

11.

Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity.

Zhang, Qin; Spears, Erick; Boone, David N; Li, Zhaoliang; Gregory, Mark A; Hann, Stephen R.

Proc Natl Acad Sci U S A ; 110(3): 978-83, 2013 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-23277542

12.

Molecular biology: A protein that spells trouble.

Boone, David.

Nature ; 508(7495): 186, 2014 Apr 10.

Artigo em Inglês | MEDLINE | ID: mdl-24717504

13.

Innate immune and chemically triggered oxidative stress modifies translational fidelity.

Netzer, Nir; Goodenbour, Jeffrey M; David, Alexandre; Dittmar, Kimberly A; Jones, Richard B; Schneider, Jeffrey R; Boone, David; Eves, Eva M; Rosner, Marsha R; Gibbs, James S; Embry, Alan; Dolan, Brian; Das, Suman; Hickman, Heather D; Berglund, Peter; Bennink, Jack R; Yewdell, Jonathan W; Pan, Tao.

Nature ; 462(7272): 522-6, 2009 Nov 26.

Artigo em Inglês | MEDLINE | ID: mdl-19940929

14.

Intestinal epithelial expression of TNFAIP3 results in microbial invasion of the inner mucus layer and induces colitis in IL-10-deficient mice.

Murphy, Stephen F; Rhee, Lesley; Grimm, Wesley A; Weber, Christopher R; Messer, Jeannette S; Lodolce, James P; Chang, Jonathan E; Bartulis, Sarah J; Nero, Thomas; Kukla, Renata A; MacDougall, Gordon; Binghay, Charles; Kolodziej, Lauren E; Boone, David L.

Am J Physiol Gastrointest Liver Physiol ; 307(9): G871-82, 2014 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-25234043

15.

Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism.

Boone, David N; Qi, Ying; Li, Zhaoliang; Hann, Stephen R.

Proc Natl Acad Sci U S A ; 108(2): 632-7, 2011 Jan 11.

Artigo em Inglês | MEDLINE | ID: mdl-21187408

16.

Intragenic Rearrangement Burden Associates with Immune Cell Infiltration and Response to Immune Checkpoint Blockade in Cancer.

Zhang, Han; Lee, Sanghoon; Muthakana, Renee R; Lu, Binfeng; Boone, David N; Lee, Daniel; Wang, Xiao-Song.

Cancer Immunol Res ; 12(3): 287-295, 2024 03 04.

Artigo em Inglês | MEDLINE | ID: mdl-38345376

17.

Retinoid orphan receptor gamma t (rorÎ³t) promotes inflammatory eosinophilia but is dispensable for innate immune-mediated colitis.

Torres-Huerta, Alvaro; Ruley-Haase, Katelyn; Reed, Theodore; Boger-May, Antonia; Rubadeux, Derek; Mayer, Lauren; Rajashekara, Arpitha Mysore; Hiller, Morgan; Frech, Madeleine; Roncagli, Connor; Pedersen, Cameron; Camacho, Mary Catherine; Hollmer, Lauren; English, Lauren; Kane, Grace; Boone, David L.

PLoS One ; 19(3): e0300892, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38512959

18.

RNA-sequencing predicts a role of androgen receptor and aldehyde dehydrogenase 1A1 in osteosarcoma lung metastases.

Heim, Tanya E; Hankins, Margaret L; Belayneh, Rebekah; Douglas, Nerone; Dinh, Vu; Kovvur, Murali; Boone, David N; Ukani, Vrutika; Bhogal, Sumail; Patel, Vaidehi; Moniz, Taylor M A; Bailey, Kelly M; John, Ivy; Schoedel, Karen; Weiss, Kurt R; Watters, Rebecca J.

Oncogene ; 43(14): 1007-1018, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38361046

19.

Vascular endothelial cell-specific disruption of the profilin1 gene leads to severe multiorgan pathology and inflammation causing mortality.

Allen-Gondringer, Abigail; Gau, David; Varghese, Christopher; Boone, David; Stolz, Donna; Larregina, Adriana; Roy, Partha.

PNAS Nexus ; 2(10): pgad305, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37781098

20.

MRTF promotes breast cancer cell motility through SRF-dependent upregulation of DIAPH3 expression.

Eder, Ian; Yu, Virginia; Chen, Fangyuan; Gau, David; Joy, Marion; Lucas, Peter; Boone, David; Lee, Adrian V; Roy, Partha.

bioRxiv ; 2023 Dec 22.

Artigo em Inglês | MEDLINE | ID: mdl-38187641

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