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1.
J Med Biol Eng ; 42(6): 853-859, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36407571

RESUMO

Purpose: In this paper, a new automated procedure based on deep learning methods for schizophrenia diagnosis is presented. Methods: To this aim, electroencephalogram signals obtained using a 32-channel helmet are prominently used to analyze high temporal resolution information from the brain. By these means, the data collected is employed to evaluate the class likelihoods using a neuronal network based on radial basis functions and a fuzzy means algorithm. Results: The results obtained with real datasets validate the high accuracy of the proposed classification method. Thus, effectively characterizing the changes in EEG signals acquired from schizophrenia patients and healthy volunteers. More specifically, values of accuracy better than 93% has been obtained in the present research. Additionally, a comparative study with other approaches based on well-knows machine learning methods shows that the proposed method provides better results than recently proposed algorithms in schizophrenia detection. Conclusion: The proposed method can be used as a diagnostic tool in the detection of the schizophrenia, helping for early diagnosis and treatment.

2.
Heliyon ; 10(4): e26298, 2024 Feb 29.
Artigo em Inglês | MEDLINE | ID: mdl-38404892

RESUMO

Electroencephalography (EEG) has been a fundamental technique in the identification of health conditions since its discovery. This analysis specifically centers on machine learning (ML) and deep learning (DL) methodologies designed for the analysis of electroencephalogram (EEG) data to categorize individuals with Alzheimer's Disease (AD) into two groups: Moderate or Advanced Alzheimer's dementia. Our study is based on a comprehensive database comprising 668 volunteers from 5 different hospitals, collected over a decade. This diverse dataset enables better training and validation of our results. Among the methods evaluated, the CNN (deep learning) approach outperformed others, achieving a remarkable classification accuracy of 97.45% for patients with Moderate Alzheimer's Dementia (ADM) and 97.03% for patients with Advanced Alzheimer's Dementia (ADA). Importantly, all the compared methods were rigorously assessed under identical conditions. The proposed DL model, specifically CNN, effectively extracts time domain features from EEG data in time, resulting in a significant reduction in learnable parameters and data redundancy.

3.
J Alzheimers Dis ; 95(4): 1667-1683, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37718814

RESUMO

BACKGROUND: In pursuit of diagnostic tools capable of targeting distinct stages of Alzheimer's disease (AD), this study explores the potential of electroencephalography (EEG) combined with machine learning (ML) algorithms to identify patients with mild or moderate AD (ADM) and advanced AD (ADA). OBJECTIVE: This study aims to assess the classification accuracy of six classical ML algorithms using a dataset of 668 patients from multiple hospitals. METHODS: The dataset comprised measurements obtained from 668 patients, distributed among control, ADM, and ADA groups, collected from five distinct hospitals between 2011 and 2022. For classification purposes, six classical ML algorithms were employed: support vector machine, Bayesian linear discriminant analysis, decision tree, Gaussian Naïve Bayes, K-nearest neighbor and random forest. RESULTS: The RF algorithm exhibited outstanding performance, achieving a remarkable balanced accuracy of 93.55% for ADA classification and 93.25% for ADM classification. The consistent reliability in distinguishing ADA and ADM patients underscores the potential of the EEG-based approach for AD diagnosis. CONCLUSIONS: By leveraging a dataset sourced from multiple hospitals and encompassing a substantial patient cohort, coupled with the straightforwardness of the implemented models, it is feasible to attain notably robust results in AD classification.

4.
Schizophr Res ; 261: 36-46, 2023 11.
Artigo em Inglês | MEDLINE | ID: mdl-37690170

RESUMO

Electroencephalography is a method of detecting and analyzing electrical activity in the brain. This electrical activity can be recorded and processed to aid in the clinical diagnosis of mental disorders. In this study, a novel system for classifying schizophrenia patients from EEG recordings is presented. The developed algorithm decomposes the EEG signals into a system of radial basis functions using the method of fuzzy means. This decomposition helps to obtain the information from the various electrodes of the EEG and allows separating between healthy controls and patients with schizophrenia. The proposed method has been compared with classical machine learning algorithms, such as, K-Nearest Neighbor, Adaboost, Support Vector Machine, and Bayesian Linear Discriminant Analysis. The results show that the proposed method obtains the highest values in terms of balanced accuracy, recall, precision and F1 score, close to 93 % in all cases. The model developed in this study can be implemented in brain activity analysis systems that help in the prediction of patients with schizophrenia.


Assuntos
Aprendizado Profundo , Esquizofrenia , Humanos , Esquizofrenia/diagnóstico , Teorema de Bayes , Eletroencefalografia/métodos , Algoritmos , Máquina de Vetores de Suporte , Processamento de Sinais Assistido por Computador
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