Detalhe da pesquisa
1.
Glycogen synthase kinase-3 (GSK3) inhibition induces prosurvival autophagic signals in human pancreatic cancer cells.
J Biol Chem
; 290(9): 5592-605, 2015 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25561726
2.
Gemcitabine promotes autophagy and lysosomal function through ERK- and TFEB-dependent mechanisms.
Cell Death Discov
; 9(1): 45, 2023 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36746928
3.
IL-15 Prevents the Development of T-ALL from Aberrant Thymocytes with Impaired DNA Repair Functions and Increased NOTCH1 Activation.
Cancers (Basel)
; 15(3)2023 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36765626
4.
Inhibition of glycogen synthase kinase-3 activity triggers an apoptotic response in pancreatic cancer cells through JNK-dependent mechanisms.
Carcinogenesis
; 33(3): 529-37, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22201186
5.
Constitutive activation of the MEK/ERK pathway inhibits intestinal epithelial cell differentiation.
Am J Physiol Gastrointest Liver Physiol
; 301(4): G719-30, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21737780
6.
The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis.
Mol Cancer
; 9: 271, 2010 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20942929
7.
The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity.
Endocrinology
; 150(1): 87-97, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18772243
8.
C-terminal deletion of NOTCH1 intracellular domain (N1ICD) increases its stability but does not amplify and recapitulate N1ICD-dependent signalling.
Sci Rep
; 7(1): 5034, 2017 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28698562
9.
The MEK/ERK pathway promotes NOTCH signalling in pancreatic cancer cells.
PLoS One
; 8(12): e85502, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24392017
10.
Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms.
J Biol Chem
; 281(10): 6395-403, 2006 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-16407209
11.
Cyclic AMP-dependent protein kinase A negatively modulates adherens junction integrity and differentiation of intestinal epithelial cells.
J Cell Physiol
; 202(1): 178-90, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15389533
12.
Regulation and role of brush border-associated ERK1/2 in intestinal epithelial cells.
Biochem Biophys Res Commun
; 311(1): 121-8, 2003 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-14575703
13.
Dual role of MEK/ERK signaling in senescence and transformation of intestinal epithelial cells.
Am J Physiol Gastrointest Liver Physiol
; 286(5): G736-46, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-14701721
14.
Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation.
J Biol Chem
; 277(10): 8226-34, 2002 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-11756422
15.
Down-regulation of MEK/ERK signaling by E-cadherin-dependent PI3K/Akt pathway in differentiating intestinal epithelial cells.
J Cell Physiol
; 199(1): 32-9, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-14978732