Detalhe da pesquisa
1.
Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.
J Biol Chem
; 289(48): 33557-67, 2014 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25320089
2.
Mammalian cell display for the discovery and optimization of antibody therapeutics.
Methods
; 65(1): 44-56, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23792919
3.
Simultaneous surface display and secretion of proteins from mammalian cells facilitate efficient in vitro selection and maturation of antibodies.
J Biol Chem
; 288(27): 19861-9, 2013 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23689374
4.
Humanization of antibodies using heavy chain complementarity-determining region 3 grafting coupled with in vitro somatic hypermutation.
J Biol Chem
; 288(11): 7688-7696, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23355464
5.
Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies.
Proc Natl Acad Sci U S A
; 108(51): 20455-60, 2011 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22158898
6.
Patient-Specific Targeting of the T-Cell Receptor Variable Region as a Therapeutic Strategy in Clonal T-Cell Diseases.
Clin Cancer Res
; 29(20): 4230-4241, 2023 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37199721
7.
Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling.
J Clin Invest
; 130(1): 315-328, 2020 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31613796
8.
Functional linkages can reveal protein complexes for structure determination.
Structure
; 15(9): 1079-89, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17850747
9.
The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function.
J Mol Biol
; 365(2): 275-83, 2007 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-17064730
10.
The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies.
Methods Mol Biol
; 1827: 479-489, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30196512
11.
Hair analysis in sled dogs (Canis lupus familiaris) illustrates a linkage of mercury exposure along the Yukon River with human subsistence food systems.
Sci Total Environ
; 385(1-3): 80-5, 2007 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17707466
12.
An exploratory study of total mercury levels in archaeological caribou hair from northwest Alaska.
Chemosphere
; 65(11): 1909-14, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16876850
13.
Utilizing logical relationships in genomic data to decipher cellular processes.
FEBS J
; 272(20): 5110-8, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16218945
14.
Mammalian cell display and somatic hypermutation in vitro for human antibody discovery.
Curr Drug Discov Technol
; 11(1): 56-64, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23978037
15.
A general approach to antibody thermostabilization.
MAbs
; 6(5): 1274-82, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25517312
16.
An integrated approach to extreme thermostabilization and affinity maturation of an antibody.
Protein Eng Des Sel
; 26(2): 151-64, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23173178
17.
High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation.
PLoS One
; 7(11): e49458, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23166676
18.
Use of logic relationships to decipher protein network organization.
Science
; 306(5705): 2246-9, 2004 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-15618515
19.
Prolinks: a database of protein functional linkages derived from coevolution.
Genome Biol
; 5(5): R35, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15128449