Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Axon Regeneration in the Central Nervous System: Facing the Challenges from the Inside.

Curcio, Michele; Bradke, Frank.

Annu Rev Cell Dev Biol ; 34: 495-521, 2018 10 06.

Artigo em Inglês | MEDLINE | ID: mdl-30044649

2.

A new "spin" on recovery after spinal cord injury.

Tedeschi, Andrea; Bradke, Frank.

Cell ; 159(7): 1494-6, 2014 Dec 18.

Artigo em Inglês | MEDLINE | ID: mdl-25525871

3.

Microtubule self-organization via protein-RNA network crosstalk.

Coles, Charlotte H; Bradke, Frank.

Cell ; 158(2): 245-247, 2014 Jul 17.

Artigo em Inglês | MEDLINE | ID: mdl-25036626

4.

Key attributes of successful research institutes.

Bradke, Frank; Maartens, Aidan; Teichmann, Sarah A.

PLoS Biol ; 21(9): e3002267, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37669250

5.

Moving through the crowd. Where are we at understanding physiological axon growth?

Alfadil, Eissa; Bradke, Frank.

Semin Cell Dev Biol ; 140: 63-71, 2023 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-35817655

6.

The centrosome protein AKNA regulates neurogenesis via microtubule organization.

Camargo Ortega, Germán; Falk, Sven; Johansson, Pia A; Peyre, Elise; Broix, Loïc; Sahu, Sanjeeb Kumar; Hirst, William; Schlichthaerle, Thomas; De Juan Romero, Camino; Draganova, Kalina; Vinopal, Stanislav; Chinnappa, Kaviya; Gavranovic, Anna; Karakaya, Tugay; Steininger, Thomas; Merl-Pham, Juliane; Feederle, Regina; Shao, Wei; Shi, Song-Hai; Hauck, Stefanie M; Jungmann, Ralf; Bradke, Frank; Borrell, Victor; Geerlof, Arie; Reber, Simone; Tiwari, Vijay K; Huttner, Wieland B; Wilsch-Bräuninger, Michaela; Nguyen, Laurent; Götz, Magdalena.

Nature ; 567(7746): 113-117, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30787442

7.

Mechanisms of Axon Growth and Regeneration: Moving between Development and Disease.

Bradke, Frank.

J Neurosci ; 42(45): 8393-8405, 2022 11 09.

Artigo em Inglês | MEDLINE | ID: mdl-36351827

8.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

Das, Richa; Schwintzer, Lukas; Vinopal, Stanislav; Aguado Roca, Eva; Sylvester, Marc; Oprisoreanu, Ana-Maria; Schoch, Susanne; Bradke, Frank; Broemer, Meike.

J Cell Sci ; 132(12)2019 06 17.

Artigo em Inglês | MEDLINE | ID: mdl-31138677

9.

Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations.

Woeste, Marina A; Stern, Sina; Raju, Diana N; Grahn, Elena; Dittmann, Dominik; Gutbrod, Katharina; Dörmann, Peter; Hansen, Jan N; Schonauer, Sophie; Marx, Carina E; Hamzeh, Hussein; Körschen, Heinz G; Aerts, Johannes M F G; Bönigk, Wolfgang; Endepols, Heike; Sandhoff, Roger; Geyer, Matthias; Berger, Thomas K; Bradke, Frank; Wachten, Dagmar.

J Biol Chem ; 294(11): 3853-3871, 2019 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-30662006

10.

Can injured adult CNS axons regenerate by recapitulating development?

Hilton, Brett J; Bradke, Frank.

Development ; 144(19): 3417-3429, 2017 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-28974639

11.

Neuronal polarization: From spatiotemporal signaling to cytoskeletal dynamics.

Schelski, Max; Bradke, Frank.

Mol Cell Neurosci ; 84: 11-28, 2017 10.

Artigo em Inglês | MEDLINE | ID: mdl-28363876

12.

Accumulation of glucosylceramide in the absence of the beta-glucosidase GBA2 alters cytoskeletal dynamics.

Raju, Diana; Schonauer, Sophie; Hamzeh, Hussein; Flynn, Kevin C; Bradke, Frank; Vom Dorp, Katharina; Dörmann, Peter; Yildiz, Yildiz; Trötschel, Christian; Poetsch, Ansgar; Breiden, Bernadette; Sandhoff, Konrad; Körschen, Heinz G; Wachten, Dagmar.

PLoS Genet ; 11(3): e1005063, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25803043

13.

Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction.

Alecu, Irina; Tedeschi, Andrea; Behler, Natascha; Wunderling, Klaus; Lamberz, Christian; Lauterbach, Mario A R; Gaebler, Anne; Ernst, Daniela; Van Veldhoven, Paul P; Al-Amoudi, Ashraf; Latz, Eicke; Othman, Alaa; Kuerschner, Lars; Hornemann, Thorsten; Bradke, Frank; Thiele, Christoph; Penno, Anke.

J Lipid Res ; 58(1): 42-59, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27881717

14.

Assembly of a new growth cone after axotomy: the precursor to axon regeneration.

Bradke, Frank; Fawcett, James W; Spira, Micha E.

Nat Rev Neurosci ; 13(3): 183-93, 2012 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-22334213

15.

A Dual SILAC Proteomic Labeling Strategy for Quantifying Constitutive and Cell-Cell Induced Protein Secretion.

Stiess, Michael; Wegehingel, Sabine; Nguyen, Chuong; Nickel, Walter; Bradke, Frank; Cambridge, Sidney B.

J Proteome Res ; 14(8): 3229-38, 2015 Aug 07.

Artigo em Inglês | MEDLINE | ID: mdl-26189946

16.

AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury.

Challagundla, Malleswari; Koch, Jan Christoph; Ribas, Vinicius Toledo; Michel, Uwe; Kügler, Sebastian; Ostendorf, Thomas; Bradke, Frank; Müller, Hans Werner; Bähr, Mathias; Lingor, Paul.

J Neurochem ; 134(2): 261-75, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25807858

17.

Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis.

Ehret, Fanny; Vogler, Steffen; Pojar, Sherin; Elliott, David A; Bradke, Frank; Steiner, Barbara; Kempermann, Gerd.

Neurobiol Dis ; 75: 131-41, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25555543

18.

The DLK signalling pathway--a double-edged sword in neural development and regeneration.

Tedeschi, Andrea; Bradke, Frank.

EMBO Rep ; 14(7): 605-14, 2013 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-23681442

19.

Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics.

Beck, Henning; Flynn, Kevin; Lindenberg, Katrin S; Schwarz, Heinz; Bradke, Frank; Di Giovanni, Simone; Knöll, Bernd.

Proc Natl Acad Sci U S A ; 109(38): E2523-32, 2012 Sep 18.

Artigo em Inglês | MEDLINE | ID: mdl-22927399

20.

Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition.

Schmidt, Mathias V; Schülke, Jan-Philip; Liebl, Claudia; Stiess, Michael; Avrabos, Charilaos; Bock, Jörg; Wochnik, Gabriela M; Davies, Heather A; Zimmermann, Nicole; Scharf, Sebastian H; Trümbach, Dietrich; Wurst, Wolfgang; Zieglgänsberger, Walter; Turck, Christoph; Holsboer, Florian; Stewart, Michael G; Bradke, Frank; Eder, Matthias; Müller, Marianne B; Rein, Theo.

Proc Natl Acad Sci U S A ; 108(41): 17213-8, 2011 Oct 11.

Artigo em Inglês | MEDLINE | ID: mdl-21969592

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