Detalhe da pesquisa
1.
Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products.
Chem Biol
; 5(10): R245-9, 1998 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-9818143
2.
Design of novel, potent, noncovalent inhibitors of thrombin with nonbasic P-1 substructures: rapid structure-activity studies by solid-phase synthesis.
J Med Chem
; 41(7): 1011-3, 1998 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-9544200
3.
Design and synthesis of a series of potent and orally bioavailable noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 position.
J Med Chem
; 41(17): 3210-9, 1998 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-9703466
4.
Discovery and development of the novel potent orally active thrombin inhibitor N-(9-hydroxy-9-fluorenecarboxy)prolyl trans-4-aminocyclohexylmethyl amide (L-372,460): coapplication of structure-based design and rapid multiple analogue synthesis on solid support.
J Med Chem
; 41(3): 401-6, 1998 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-9464370
5.
Inhibition of thrombin by peptides containing Lysyl-alpha-keto carbonyl derivatives.
Thromb Haemost
; 74(4): 1107-12, 1995 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-8560421
6.
Cytoskyrins A and B, new BIA active bisanthraquinones isolated from an endophytic fungus.
Org Lett
; 2(25): 4047-9, 2000 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-11112640
7.
Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA.
Org Lett
; 3(13): 1981-4, 2001 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-11418029
8.
The cytosporones, new octaketide antibiotics isolated from an endophytic fungus.
Org Lett
; 2(25): 4043-6, 2000 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-11112639
9.
A super active cyclic hexapeptide analog of somatostatin.
Life Sci
; 34(14): 1371-8, 1984 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-6143233
10.
Biological activity of guanacastepene, a novel diterpenoid antibiotic produced by an unidentified fungus CR115.
J Antibiot (Tokyo)
; 53(3): 256-61, 2000 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-10819296
11.
Stereochemical relationships in spirovetivane sesquiterpenes: the total synthesis of hinesol.
Tetrahedron Lett
; (18): 1387-90, 1969 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-5794433
12.
CR377, a new pentaketide antifungal agent isolated from an endophytic fungus.
J Nat Prod
; 63(10): 1447-8, 2000 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-11076576
13.
ZmaR, a novel and widespread antibiotic resistance determinant that acetylates zwittermicin A.
J Bacteriol
; 181(17): 5455-60, 1999 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-10464220
14.
Synthesis and solution conformation of c(D-Trp-D-Cys(SO3-Na+)-Pro-D-Val-Leu), a potent endothelin-A receptor antagonist.
Int J Pept Protein Res
; 42(2): 194-203, 1993 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-8407113
15.
Recombinant leech antiplatelet protein prevents collagen-mediated platelet aggregation but not collagen graft thrombosis in baboons.
Arterioscler Thromb
; 13(11): 1593-601, 1993 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-8218100
16.
The solution conformation of Ac-Pen-Arg-Gly-Asp-Cys-OH, a potent fibrinogen receptor antagonist.
Biopolymers
; 33(8): 1287-97, 1993 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-8364159
17.
Amino acid sequence of homologous rat atrial peptides: natriuretic activity of native and synthetic forms.
Proc Natl Acad Sci U S A
; 81(9): 2640-4, 1984 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-6232612
18.
Amide and alpha-keto carbonyl inhibitors of thrombin based on arginine and lysine: synthesis, stability and biological characterization.
Bioorg Med Chem
; 3(8): 1063-78, 1995 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-7582980
19.
NMR and molecular modeling characterization of RGD containing peptides.
Int J Pept Protein Res
; 39(1): 63-76, 1992 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-1634331
20.
HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins.
Biochem Biophys Res Commun
; 156(1): 297-303, 1988 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-3052448