Detalhe da pesquisa
1.
Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site.
J Biol Chem
; 297(2): 100899, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157288
2.
A lipid site shapes the agonist response of a pentameric ligand-gated ion channel.
Nat Chem Biol
; 15(12): 1156-1164, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31591563
3.
An allosteric binding site of the α7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein.
J Biol Chem
; 293(7): 2534-2545, 2018 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29237730
4.
Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.
Proc Natl Acad Sci U S A
; 113(43): E6696-E6703, 2016 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791038
5.
Family of prokaryote cyclic nucleotide-modulated ion channels.
Proc Natl Acad Sci U S A
; 111(21): 7855-60, 2014 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24821777
6.
Different ligands of the TRPV3 cation channel cause distinct conformational changes as revealed by intrinsic tryptophan fluorescence quenching.
J Biol Chem
; 290(20): 12964-74, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25829496
7.
Structural basis of ligand recognition in 5-HT3 receptors.
EMBO Rep
; 14(1): 49-56, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23196367
8.
Molecular actions of smoking cessation drugs at α4ß2 nicotinic receptors defined in crystal structures of a homologous binding protein.
Proc Natl Acad Sci U S A
; 109(23): 9173-8, 2012 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22619328
9.
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines.
Proc Natl Acad Sci U S A
; 109(44): E3028-34, 2012 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23035248
10.
Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).
J Biol Chem
; 288(12): 8355-8364, 2013 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23364792
11.
A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors.
PLoS Biol
; 9(3): e1001034, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21468359
12.
Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein.
J Biol Chem
; 286(6): 4420-8, 2011 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21115477
13.
The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.
Nat Commun
; 13(1): 4543, 2022 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35927270
14.
Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site.
Elife
; 92020 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31990273
15.
Author Correction: The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.
Nat Commun
; 15(1): 4532, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38806512
16.
Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues.
PLoS One
; 11(3): e0151183, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26999666
17.
Structural hot spots for the solubility of globular proteins.
Nat Commun
; 7: 10816, 2016 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26905391
18.
Structure of the SthK carboxy-terminal region reveals a gating mechanism for cyclic nucleotide-modulated ion channels.
PLoS One
; 10(1): e0116369, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25625648
19.
Identification of a novel PEX14 mutation in Zellweger syndrome.
BMJ Case Rep
; 20092009.
Artigo
em Inglês
| MEDLINE | ID: mdl-21686775