Detalhe da pesquisa
1.
Implementation of toxicokinetics in toxicity studies--Toxicokinetics of 4-methylanisole and its metabolites in juvenile and adult rats.
Regul Toxicol Pharmacol
; 73(1): 55-64, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26140820
2.
Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats.
Part Fibre Toxicol
; 11: 30, 2014 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24993397
3.
Effects of probiotic bacteria on the bioaccessibility of aflatoxin B(1) and ochratoxin A using an in vitro digestion model under fed conditions.
J Environ Sci Health B
; 44(5): 472-80, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20183052
4.
Structure elucidation of aplidine metabolites formed in vitro by human liver microsomes using triple quadrupole mass spectrometry.
J Mass Spectrom
; 40(6): 821-31, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15892174
5.
Arsenic: bioaccessibility from seaweed and rice, dietary exposure calculations and risk assessment.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
; 31(12): 1993-2003, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25393691
6.
Fate in digestion in vitro of several food components, including some toxic compounds coming from omega-3 and omega-6 lipids.
Food Chem Toxicol
; 49(1): 115-24, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20937346
7.
Effect of administration route on the biodistribution and shedding of replication-deficient HAdV-5: a qualitative modelling approach.
Curr Gene Ther
; 10(2): 107-27, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20222861
8.
Effect of administration route on the biodistribution and shedding of replication-deficient AAV2: a qualitative modelling approach.
Curr Gene Ther
; 10(2): 91-106, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20222862
9.
In vitro characterization of the human biotransformation pathways of aplidine, a novel marine anti-cancer drug.
Invest New Drugs
; 25(1): 9-19, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16633717
10.
In vitro characterization of the human biotransformation and CYP reaction phenotype of ET-743 (Yondelis, Trabectidin), a novel marine anti-cancer drug.
Invest New Drugs
; 24(1): 3-14, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16379042
11.
Consumer product in vitro digestion model: Bioaccessibility of contaminants and its application in risk assessment.
Regul Toxicol Pharmacol
; 44(2): 161-71, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16337324
12.
Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines.
Toxicol Appl Pharmacol
; 211(1): 1-10, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15975613
13.
In-vitro cytotoxicity of ET-743 (Trabectedin, Yondelis), a marine anti-cancer drug, in the Hep G2 cell line: influence of cytochrome P450 and phase II inhibition, and cytochrome P450 induction.
Anticancer Drugs
; 16(9): 935-43, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16162970
14.
In vitro characterization of the biotransformation of thiocoraline, a novel marine anti-cancer drug.
Invest New Drugs
; 22(3): 241-51, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15122071
15.
An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons.
Toxicol Appl Pharmacol
; 189(3): 233-46, 2003 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12791308