Detalhe da pesquisa
1.
Dimers of D76N-ß2-microglobulin display potent antiamyloid aggregation activity.
J Biol Chem
; 298(12): 102659, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36328246
2.
The role of the IT-state in D76N ß2-microglobulin amyloid assembly: A crucial intermediate or an innocuous bystander?
J Biol Chem
; 295(35): 12474-12484, 2020 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32661194
3.
The Leishmania PABP1-eIF4E4 interface: a novel 5'-3' interaction architecture for trans-spliced mRNAs.
Nucleic Acids Res
; 47(3): 1493-1504, 2019 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30476241
4.
Farseer-NMR: automatic treatment, analysis and plotting of large, multi-variable NMR data.
J Biomol NMR
; 71(1): 1-9, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-29752607
5.
Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting.
Biochem Soc Trans
; 46(6): 1753-1770, 2018 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30545934
6.
Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.
J Biol Chem
; 291(4): 1703-1718, 2016 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26565026
7.
Evaluation of 15N-detected H-N correlation experiments on increasingly large RNAs.
J Biomol NMR
; 69(1): 31-44, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28879611
8.
Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups.
Org Biomol Chem
; 14(15): 3782-6, 2016 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27005701
9.
Target-based whole-cell screening by ¹Hâ NMR spectroscopy.
Angew Chem Int Ed Engl
; 54(16): 4764-7, 2015 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25693499
10.
Small-molecule proteomimetic inhibitors of the HIF-1α-p300 protein-protein interaction.
Chembiochem
; 15(8): 1083-7, 2014 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24782431
11.
Real-time monitoring of New Delhi metallo-ß-lactamase activity in living bacterial cells by 1Hâ NMR spectroscopy.
Angew Chem Int Ed Engl
; 53(8): 2130-3, 2014 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24458501
12.
Tuning the rate of aggregation of hIAPP into amyloid using small-molecule modulators of assembly.
Nat Commun
; 13(1): 1040, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35210421
13.
RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site.
Nat Commun
; 12(1): 4045, 2021 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34193876
14.
NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 3 in apo state and in complex with inhibitor PD173074.
Biomol NMR Assign
; 12(2): 231-235, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29582384
15.
Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System.
Structure
; 26(3): 446-458.e8, 2018 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29478821
16.
Towards "bionic" proteins: replacement of continuous sequences from HIF-1α with proteomimetics to create functional p300 binding HIF-1α mimics.
Chem Commun (Camb)
; 52(31): 5421-4, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27009828
17.
Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use.
Oncotarget
; 7(17): 24252-68, 2016 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26992226
18.
Structural and dynamic insights into the energetics of activation loop rearrangement in FGFR1 kinase.
Nat Commun
; 6: 7877, 2015 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26203596
19.
Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies.
Mol Biosyst
; 11(10): 2738-49, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26135796
20.
Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activation.
J Med Chem
; 58(5): 2265-74, 2015 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25695162