Detalhe da pesquisa
1.
SARS-CoV-2 DNA Vaccine INO-4800 Induces Durable Immune Responses Capable of Being Boosted in a Phase 1 Open-Label Trial.
J Infect Dis
; 225(11): 1923-1932, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35079784
2.
Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms.
J Immunol
; 205(3): 648-660, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32591390
3.
SARS-CoV-2 Assays To Detect Functional Antibody Responses That Block ACE2 Recognition in Vaccinated Animals and Infected Patients.
J Clin Microbiol
; 58(11)2020 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32855181
4.
Anti-OspA DNA-Encoded Monoclonal Antibody Prevents Transmission of Spirochetes in Tick Challenge Providing Sterilizing Immunity in Mice.
J Infect Dis
; 219(7): 1146-1150, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30476132
5.
Intradermal SynCon® Ebola GP DNA Vaccine Is Temperature Stable and Safely Demonstrates Cellular and Humoral Immunogenicity Advantages in Healthy Volunteers.
J Infect Dis
; 220(3): 400-410, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30891607
6.
Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines.
J Infect Dis
; 219(4): 544-555, 2019 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30304515
7.
Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques.
J Virol
; 92(15)2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29793957
8.
DNA Prime-Boost Vaccine Regimen To Increase Breadth, Magnitude, and Cytotoxicity of the Cellular Immune Responses to Subdominant Gag Epitopes of Simian Immunodeficiency Virus and HIV.
J Immunol
; 197(10): 3999-4013, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27733554
9.
Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial.
Lancet
; 386(10008): 2078-2088, 2015 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26386540
10.
DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge.
Proc Natl Acad Sci U S A
; 110(8): 2975-80, 2013 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23359688
11.
A synthetic codon-optimized hepatitis C virus nonstructural 5A DNA vaccine primes polyfunctional CD8+ T cell responses in wild-type and NS5A-transgenic mice.
J Immunol
; 190(3): 1113-24, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23284053
12.
The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production.
J Biol Chem
; 288(9): 6763-76, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23297419
13.
A heterologous prime/boost vaccination strategy enhances the immunogenicity of therapeutic vaccines for hepatitis C virus.
J Infect Dis
; 208(6): 1008-19, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23776192
14.
Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo.
Cell Rep Med
; 3(7): 100693, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35839767
15.
Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates.
Vaccine
; 40(21): 2960-2969, 2022 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35428500
16.
Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.
Nat Commun
; 13(1): 695, 2022 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35121758
17.
Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection.
Cell Rep
; 38(5): 110318, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35090597
18.
DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Nat Commun
; 13(1): 5886, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36202799
19.
Piezoelectric permeabilization of mammalian dermal tissue for in vivo DNA delivery leads to enhanced protein expression and increased immunogenicity.
Hum Vaccin
; 7 Suppl: 22-8, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21263230
20.
Live Virus Neutralisation of the 501Y.V1 and 501Y.V2 SARS-CoV-2 Variants following INO-4800 Vaccination of Ferrets.
Front Immunol
; 12: 694857, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34248993